대한치과교정학회지 (The korean journal of orthodontics)

  • 제52권2호
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  • Pages.142-149
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  • 2022
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  • 2234-7518(pISSN)
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  • 2005-372X(eISSN)
대한치과교정학회 (The Korean Association Of Orthodontists)
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Evaluation of periodontal parameters and gingival crevicular fluid cytokines in children with anterior open bite receiving passive orthodontic treatment with a spur

  • Tou, Gabriel Antonio dos Anjos (Department of Restorative Dentistry, Faculty of Dentistry, Federal University of Minas Gerais, Belo Horizonte) ;
  • Diniz, Ivana Marcia Alves (Department of Restorative Dentistry, Faculty of Dentistry, Federal University of Minas Gerais, Belo Horizonte) ;
  • Ferreira, Marcus Vinicius Lucas (Department of Restorative Dentistry, Faculty of Dentistry, Federal University of Minas Gerais, Belo Horizonte) ;
  • Mesquita, Ricardo Alves (Department of Oral Pathology and Surgery, Faculty of Dentistry, Federal University of Minas Gerais) ;
  • Yamauti, Monica (Department of Restorative Dentistry, Division of Oral Health Science, Graduate School and Faculty of Dental Medicine, Hokkaido University) ;
  • Silva, Tarcilia Aparecida (Department of Oral Pathology and Surgery, Faculty of Dentistry, Federal University of Minas Gerais) ;
  • Macari, Soraia (Department of Restorative Dentistry, Faculty of Dentistry, Federal University of Minas Gerais, Belo Horizonte)
  • 투고 : 2021.06.04
  • 심사 : 2021.10.22
  • 발행 : 2022.03.25
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초록

Objective: To evaluate clinical parameters and gingival crevicular fluid (GCF) cytokines in children with anterior open bite receiving passive orthodontic treatment with spurs. Methods: Twenty children with indications for interceptive orthodontic treatment, an anterior open bite, and good oral hygiene and periodontal health were included in this study. GCF samples were collected from the mandibular and maxillary central incisors before (baseline) and 24 hours and 7 days after spur bonding. Clinical and periodontal examinations and cytokine analyses were performed. Results: At 7 days after spur attachment, gingival bleeding in the mandibular group was increased relative to that in the maxillary group. Visible plaque was correlated with gingival bleeding at 7 days and the GCF volume at 24 hours after spur attachment. Compared with those at baseline, interleukin (IL)-8 levels in the maxillary group and IL-1β levels in both tooth groups increased at both 24 hours and 7 days and at 7 days, respectively. At 24 hours, IL-8, IL-1β, and IL-6 levels were higher in the maxillary group than in the mandibular group. Cytokine production was positively correlated with increased GCF volume, but not with gingival bleeding, visible plaque, or probing depth. Conclusions: Although orthodontic treatment with spurs in children resulted in increased gingival bleeding around the mandibular incisors, IL levels were higher around the maxillary incisors and not correlated with periodontal parameters. Increased cytokine levels in GCF may be associated with the initial tooth movement during open bite correction with a passive orthodontic appliance in children.

키워드

과제정보

The authors thank the Program for Technological Development in Tools for Health-RPT-FIOCRUZ for permitting the use of its facilities, with special thanks to Elaine Speziali de Faria e Dayane Andriotti Otta for the helpful assistance with CBA analysis. This study was supported by Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) and Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq).

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