Journal of Korean Medicine for Obesity Research (한방비만학회지)

The Society of Korean Medicine for obesity Research (한방비만학회)
권호 표지
DOI QR코드

DOI QR Code

Effect of Weight Loss and Improvement of Liver Function through Korean Medicinal Treatment: Case Report

한약치료의 체중 감량 효과와 간기능 개선: 증례보고

  • Received : 2022.08.02
  • Accepted : 2022.11.16
  • Published : 2022.12.30
Download PDF
⟨ Previous Next ⟩

Abstract

Obesity is known as the most common risk factor for non-alcoholic fatty liver disease. Weight loss is needed to prevent liver function damage from progressing to non-alcoholic hepatosteatosis (NASH) and NASH-related liver cirrhosis. The purpose of this study was to observe the recovery of liver function in obese patients with liver dysfunction through traditional Korean obesity treatment. Body weight, liver function levels and renal function levels were examined by prescribing traditional Korean medicine in obese patients with mild elevation of liver function test. Blood tests were conducted at intervals of one month, and it was observed that liver function recovered to the normal range in three patients.

Keywords

References

  1. Ministry of Health and Welfare & Korea Centers for Disease Control and Prevention. Korea Health Statistics 2020: Korea National Health and Nutrition Examination Survey (KNHANES VIII-2). Cheongju : Korea Disease Control and Prevention Agency. 2022.
  2. Chew HSJ, Lopez V. Global impact of COVID-19 on weight and weight-related behaviors in the adult population: a scoping review. Int J Environ Res Public Health. 2021 ; 18 : 1876.
  3. Grundy SM. Obesity, metabolic syndrome, and cardiovascular disease. J Clin Endocrinol Metab. 2004 ; 89 : 2595-600. https://doi.org/10.1210/jc.2004-0372
  4. Clain DJ, Lefkowitch JH. Fatty liver disease in morbid obesity. Gastroenterol Clin North Am. 1987 ; 16 : 239-52. https://doi.org/10.1016/S0889-8553(21)00289-2
  5. EBM-based Obesity Korean Medicine Clinical Practice Guidelines Development Committee (Korea Institute of Oriental Medicine, The Society of Korean Medicine for Obesity Research). Korean medicine clinical practice guidelines-obesity, Daejeon, Republic of Korea. Seoul : Elsevier. 2016.
  6. Heo JK, Hwang DS, Lee CH, Lee KS. A case study on a non-alcoholic fatty liver disease (NAFLD) patient improved by the oriental obesity therapy program. J Korean Med Obes Res. 2007 ; 7(2) : 85-94.
  7. Jin YH, Kim KS, Han IY, Lee HB. Influence of prescribed Gamitaeeumjowi-tang on liver function : prospective single-center pilot study. J Korean Med Obes Res. 2010 ; 10(1) : 29-40.
  8. Ebbeling CB, Feldman HA, Klein GL, Wong JMW, Bielak L, Steltz SK, et al. Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial. BMJ. 2018 ; 363 : k4583.
  9. Rogovik AL, Goldman RD. Ketogenic diet for treatment of epilepsy. Can Fam Physician. 2010 ; 56 : 540-2.
  10. Ha K, Song Y. Low-carbohydrate diets in Korea: why does it matter, and what is next? J Obes Metab Syndr. 2021 ; 30 : 222-32. https://doi.org/10.7570/jomes21051
  11. Shilpa J, Mohan V. Ketogenic diets: boon or bane? Indian Journal of Medical Research. 2018 ; 148(3) : 251-3. https://doi.org/10.4103/ijmr.ijmr_1666_18
  12. Choi H, Seo GS, Shin WY. The retrospective analysis of obesity and overweight female patients with clinical treatment including herbal medicine. J Korean Obstet Gynecol. 2016 ; 29(3) : 35-46. https://doi.org/10.15204/JKOBGY.2016.29.3.035
  13. Hwang MJ, Shin HD, Song MY. Literature review of herbal medicines on treatment of obesity since 2000: mainly about Ephedra Herba. J Korean Med Obes Res. 2007 ; 7(1) : 39-54.
  14. Ryu SM, Jung SH, Lee JS, Kim SS, Shin HD. The effect of very low calorie diet and Chegamuiyiin-tang on bone mineral density. J Korean Med Obes Res. 2005 ; 5(1) : 87-95.
  15. Son GH, Shin SW, Kwon YK, Kim SC, Park JH. Comparison of immunomodualtory effects of water-extracted Aconiti Iateralis Preparata Radix, Zingiberis Rhizoma, Cinnamomi Cortex and Evodiae Fructus. Korean J Physiology & Pathology. 2005 ; 19(4) : 1000-10.
  16. Choi HS, Jeong TY. One case of drug-induced liver injury treated with Saenggangeonbi-tang. Korean J Orient Int Med. 2004 ; 25(4) : 207-11.
  17. Hong SH, Kwon OS, Kim SH, Kim HJ, Kim KT, Park SE, et al. Effects of Injinoryung-San on alcoholic hepatitis. Korean J Oriental Physiology & Pathology. 2008 ; 22(1) : 204-8.
  18. Han CW, Joo MS, Lee JH. Comparison of the therapeutic efficacy of Rhizoma Alismatis, Fructus Crataegi, Fructus Lycii, Radix Curcumae, Radix Salviae Miltiorrhizae, Herba Artemisiae Scopariaeon the experimental cellular model of nonalcoholic fatty liver disease. Korean J Orient Int Med. 2012 ; 33(4) : 533-42.
  19. Kim I. In vitro hepatocyte inflammation by Ephedra sinica extracts. Korean Journal of Food Science and Technology. 2019 ; 51(1) : 24-8.
  20. Lim K, Kang M, Park J. Association between fasting ketonuria and advanced liver fibrosis in non-alcoholic fatty liver disease patients without prediabetes and diabetes mellitus. Nutrients. 2021 ; 13(10) : 3400.
  21. Gibson AA, Seimon RV, Lee CMY, Ayre J, Franklin J, Markovic TP, et al. Do ketogenic diets really suppress appetite? A systematic review and meta-analysis. Obes Rev. 2015; 16(1) : 64-76. https://doi.org/10.1038/oby.2007.31