과제정보
The authors are grateful to Dr. Wang H, Qinghai Centers for Diseases Control and Prevention for his gift of E. multilocularis protoscolex collected from experimentally infected mouse. This work was supported in part by the Korea Research Foundation (2019R1I1A1AO1058525).
참고문헌
- Eckert J, Conraths FJ, Tackmann K. Echinococcosis: an emerging or re-emerging zoonosis? Int J Parasitol 2000; 30: 1283-1294. https://doi.org/10.1016/s0020-7519(00)00130-2
- Craig PS, Li T, Qiu J, Zhen R, Wang Q, Giraudoux P, Ito A, Heath D, Warnock B, Schantz P, Yang W. Echinococcosis and Tibetan communities. Emerg Infect Dis 2008; 14: 1674-1675. https://doi.org/10.3201/eid1410.071636
- Spiliotis M, Lechner S, Tappe D, Scheller C, Krohne G, Brehm K. Transient transfection of Echinococcus multilocularis primary cells and complete in vitro regeneration of metacestode vesicles. Int J Parasitol 2008; 38: 1025-1039. https://doi.org/10.1016/j.ijpara.2007.11.002
- Piarroux M, Piarroux R, Giorgi R, Knapp J, Bardonnet K, Sudre B, Watelet J, Dumortier J, Gerard A, Beytout J, Abergel A, Mantion G, Vuitton DA, Bresson-Hadni S. Clinical features and evolution of alveolar echinococcosis in France from 1982 to 2007: results of a survey in 387 patients. J Hepatol 2011; 55: 1025-1033. https://doi.org/10.1016/j.jhep.2011.02.018
- Brunetti E, Kern P, Vuitton DA, Writing Panel for the WHO-IWGE. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. Acta Trop 2010; 114:1-16. https://doi.org/10.1016/j.actatropica.2009.11.001
- Kantarci M, Bayraktutan U, Karabulut N, Aydinli B, Ogul H, Yuce I, Calik M, Eren S, Atamanalp SS, Oto A. Alveolar echinococcosis: spectrum of findings at cross-sectional imaging. Radiographics 2012; 32: 2053-2070. https://doi.org/ 10.1148/rg.327125708
- Bellanger AP, Wang J, Gbaguidi-Haore H, Barrera C, Bresson-Hadni S, Zlobec I, Lachenmayer A, Richou C, Turco C, Gottstein B, Millon L, Beldi G. Investigating new serological and tissue markers for the follow-up of patients operated for alveolar echinococcosis. Parasite Immunol 2021;43: e12827. https://doi.org/10.1111/pim.12827
- Vogel M, Gottstein B, Muller N, Seebeck T. Production of a recombinant antigen of Echinococcus multilocularis with high immunodiagnostic sensitivity and specificity. Mol Biochem Parasitol 1988; 31: 117-125. https://doi.org/10.1016/0166-6851(88)90162-4
- Deplazes P, Gottstein B. A monoclonal antibody against Echinococcus multilocularis Em2 antigen. Parasitology 1991; 103: 41-49. https://doi.org/10.1017/s0031182000059278
- Hulsmeier AJ, Gehrig PM, Geyer R, Sack R, Gottstein B, Deplazes P, Kohler P. A major Echinococcus multilocularis antigen is a mucin type glycoprotein. J Biol Chem 2002; 277: 5742-5748. https://doi.org/10.1074/jbc.M107161200
- Yamano K, Koizumi A, Takeda T, Kiuchi F, Hada N. Gal α1-4Gal β1-3GalNAc is the dominant epitope of Em2 antigen, the mucin-type glycoprotein from Echinococcus multilocularis. Parasitol Res 2012; 111: 795-805. https://doi.org/10.1007/s00436-012-2902-1
- Frosch PM, Frosch M, Pfister T, Schaad V, Bitter-Suermann D. Cloning and characterisation of an immunodominant major surface antigen of Echinococcus multilocularis. Mol Biochem Parasitol 1991; 48: 121-130. https://doi.org/10.1016/0166-6851(91)90108-i
- Carmena D, Benito A, Eraso E. The immunodiagnosis of Echinococcus multilocularis infection. Clin Microbiol Infect 2007; 13: 460-475. https://doi.org/10.1111/j.1469-0691.2007.01665.x
- Ishikawa Y, Sako Y, Itoh S, Ohtake T, Kohgo Y, Matsuno T, Ohsaki Y, Miyokawa N, Nakao M, Nakaya K, Ito A. Serological monitoring of progression of alveolar echinococcosis with multiorgan involvement by use of recombinant Em18. J Clin Microbiol 2009; 47: 3191-3196. https://doi.org/10.1128/JCM.01111-09
- Sako Y, Nakao M, Nakaya K, Yamasaki H, Gottstein B, Lightowers MW, Schantz PM, Ito A. Alveolar echinococcosis: characterization of diagnostic antigen Em18 and serological evaluation of recombinant Em18. J Clin Microbiol 2002; 40: 2760-2765. https://doi.org/10.1128/JCM.40.8.2760-2765.2002
- Kern P. Clinical features and treatment of alveolar echinococcosis. Curr Opin Infect Dis 2010; 23: 505-512. https://doi.org/10.1097/QCO.0b013e32833d7516
- Ahn CS, Cai H, Kim JG, Han X, Ma X, Bae YA, Yang HJ, Kang I, Wang H, Kong Y. An Echinococcus multilocularis antigen B3 proteoform that shows specific antibody responses to active-stage alveolar echinococcosis. J Clin Microbiol 2015; 53: 3310-3317. https://doi.org/10.1128/JCM.01362-15
- Sulima M, Nahorski W, Gorycki T, Wolyniec W, Waz P, FelczakKorzybska I, Szostakowska B, Sikorska K. Ultrasound images in hepatic alveolar echinococcosis and clinical stage of the disease. Adv Med Sci 2019; 64: 324-330. https://doi.org/10.1016/j.advms.2019.04.002
- Han X, Kim JG, Wang H, Cai H, Ma X, Duong DH, Ahn CS, Kang I, Kong Y. Survey of echinococcoses in southeastern Qinghai Province, China, and serodiagnostic insights of recombinant Echinococcus granulosus antigen B isoforms. Parasite Vectors 2019; 12: 323. https://doi.org/10.1186/s13071-019-3569-6
- Ahn CS, Bae YA, Kim SH, Kim JG, Yu JR, Yang HJ, Eom KS, Wang H, Kang I, Yang Y, Kong Y. Spatiotemporal expression patterns and antibody reactivity of Taeniidae endophilin B1. J Clin Microbiol 2016; 54: 2553-2562. https://doi.org/10.1128/JCM.01135-16
- Dawar FU, Xiong Y, Khattak MNK, Li J, Lin L, Mei J. Potential role of cyclophilin A in regulating cytokine secretion. J Leukoc Biol 2017; 102: 989-992. https://doi.org/10.1189/jlb.3RU0317-090RR
- Unno H, Matsuyama K, Tsuji Y, Goda S, Hiemori K, Tateno H, Hirabayashi J, Hatakeyama T. Identification, characterization, and X-ray crystallographic analysis of a novel type of mannose-specific lectin CGL1 from the pacific oyster Crassostrea gigas. Sci Rep 2016; 6: 29135. https://doi.org/10.1038/srep29135
- Nakaya K, Mamuti W, Xiao N, Sato MO, Wandra T, Nakao M, Sako Y, Yamasaki H, Ishikawa Y, Craig PS, Schantz PM, Ito A. Usefulness of severe combined immunodeficiency (scid) and inbred mice for studies of cysticercosis and echinococcosis. Parasitol Int 2006; 55 (suppl): 91-97. https://doi.org/10.1016/j.parint.2005.11.014
- Muller N, Frei E, Nunez S, Gottstein B. Improved serodiagnosis of alveolar echinococcosis of humans using an in vitro-produced Echinococcus multilocularis antigen. Parasitology 2007; 134: 879-888. https://doi.org/10.1017/S0031182006002083
- Hemphill A, Gottstein B. Immunology and morphology studies on the proliferation of in vitro cultivated Echinococcus multilocularis metacestodes. Parasitol Res 1995; 81: 605-614. https://doi.org/10.1007/BF00932028
- Matsumoto J, Kouguchi H, Oku Y, Yagi K. Primary alveolar echinococcosis: course of larval development and antibody responses in intermediate host rodents with different genetic backgrounds after oral infection with eggs of Echinococcus multilocularis. Parasitol Int 2010; 59: 435-444. https://doi.org/10.1016/j.parint.2010.06.003
- Tsai IJ, Zarowiecki M, Holroyd N, Garciarrubio A, SanchezFlores A, Brooks KL, Tracey A, Bobes RJ, Fragoso G, Sciutto E, Aslett M, Beasley H, Bennett HM, Cai X, Camicia F, Clark R, Cucher M, De Silva N, Day TA, Deplazes P, Estrada K, Fernandez C, Holland PWH, Hou J, Hu S, Huckvale T, Hung SS, Kamenetzky L, Keane JA, Kiss F, Koziol U, Lambert O, Liu K, Luo X, Luo Y, Macchiaroli N, Nichol S, Paps J, Parkinson J, Pouchkina-Stantcheva N, Riddiford N, Rosenzvit M, Salinas G, Wasmuth JD, Zamanian M, Zheng Y; Taenia solium Genome Consortium, Cai J, Soberon X, Olson PD, Laclette JP, Brehm K, Berriman M. The genomes of four tapeworm species reveal adaptations to parasitism. Nature 2013; 496: 57-63. https://doi.org/10.1038/nature12031
- Ahn CS, Kim JG, Han X, Kang I, Kong Y. Comparison of Echinococcus multilocularis and Echinococcus granulosus hydatid fluid proteome provides molecular strategies for specialized host-parasite interactions. Oncotarget 2017; 8: 97009-97024. https://doi.org/10.18632/oncotarget.20761
- Twu O, Johnson PJ. Parasite extracellular vesicles: mediators of intercellular communication. PLoS Pathog 2014; 10: e1004289. https://doi.org/10.1371/journal.ppat.1004289
- Nicolao MC, Rodriguez Rodrigues C, Cumino AC. Extracellular vesicles from Echinococcus granulosus larval stage: isolation, characterization and uptake by dendritic cells. PLoS Negl Trop Dis 2019; 13: e0007032. https://doi.org/10.1371/journal.pntd.0007032
- Drurey C, Maizels RM. Helminth extracellular vesicles: interactions with the host immune system. Mol Immunol 2021; 137: 124-133. https://doi.org/10.1016/j.molimm.2021.06.017
- Ancarola ME, Marcilla A, Herz M, Macchiaroli N, Perez M, Asurmendi S, Brehm K, Poncini C, Rosenzvit M, Cucher M. Cestode parasites release extracellular vesicles with microRNAs and immunodiagnostic protein cargo. Int J Parasitol 2017; 47: 675-686. https://doi.org/10.1016/j.ijpara.2017.05.003
- Hernandez-Gonzalez A, Santivanez S, Garcia HH, Rodriguez S, Munoz S, Ramos G, Orduna A, Siles-Lucas M. Improved serodiagnosis of cystic echinococcosis using the new recombinant 2B2t antigen. PLoS Negl Trop Dis 2012; 6: e1714. https://doi.org/10.1371/journal.pntd.0001714
- Ahn CS, Kim JG, Han X, Bae YA, Park WJ, Kang I, Wang H, Kong Y. Biochemical characterization of Echinococcus multilocularis antigen B3 reveals insight into adaptation and maintenance of parasitic homeostasis at the host-parasite interface. J Proteome Res 2017; 16: 806-823. https://doi.org/10.1021/acs.jproteome.6b00799