Korean Journal of Agricultural Science (농업과학연구)

Institute of Agricultural Science, CNU (충남대학교 농업과학연구소)
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Effects of beekeeping by-products in drinking water on the growth performance and intestinal and fecal microflora of ICR mice

  • Se Yeon, Chang (Department of Animal Science, Chungbuk National University) ;
  • Ji Hwan, Lee (Department of Poultry Science, University of Georgia) ;
  • Han Jin, Oh (Department of Animal Science, Chungbuk National University) ;
  • Yong Ju, Kim (Department of Animal Science, Chungbuk National University) ;
  • Jae Woo, An (Department of Animal Science, Chungbuk National University) ;
  • Young Bin, Go (Department of Animal Science, Chungbuk National University) ;
  • Dong Cheol, Song (Department of Animal Science, Chungbuk National University) ;
  • Hyun Ah, Cho (Department of Animal Science, Chungbuk National University) ;
  • Yun A, Kim (Department of Animal Science, Chungbuk National University) ;
  • Sang Hun, Park (Department of Animal Science, Chungbuk National University) ;
  • Yun Hwan, Park (Department of Animal Science, Chungbuk National University) ;
  • Gyu Tae, Park (Department of Animal Science, Chungbuk National University) ;
  • Se Hyuk, Oh (Department of Animal Science, Chungbuk National University) ;
  • Jung Seok, Choi (Department of Animal Science, Chungbuk National University) ;
  • Jin Ho, Cho (Department of Animal Science, Chungbuk National University)
  • Received : 2022.06.21
  • Accepted : 2022.07.27
  • Published : 2022.09.01
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Abstract

The aim of this study was to evaluate the effect of beekeeping by-products added to drinking water on the growth performance and intestinal and fecal microflora of Institute of Cancer Research (ICR) mice. A total of 72 five-week-old ICR mice with an initial body weight (BW) of 24.57 ± 0.60 g were used in a two-week experiment. The four treatment groups were as follows; 1) CON, normal distilled water; 2) T1, CON with 0.7% beehive extract; 3) T2, CON with 0.7% propolis (PRO); and 4) T3, CON with 0.7% royal jelly (RJ). Each treatment consisted of 6 replicate cages with 3 mice per cage. At 0 - 1 week, T3 showed a significantly higher (p < 0.05) body weight gain (BWG) and feed efficiency (G : F) than that of CON. Compared with CON, T2 showed a significantly higher (p < 0.05) BWG and feed intake at 1 - 2 weeks. During the entire period, T2 and T3 showed a significantly higher (p < 0.05) BWG and G : F compared to CON. The amount of Salmonella and Lactobacillus in the large intestine was significantly decreased and increased (p < 0.05) in T2 and T3, respectively, compared to CON. The amount of Escherichia coli in the fecal matter was significantly reduced (p < 0.05) compared to CON in all treatment groups to which beekeeping by-products were added. In conclusion, the addition of PRO or RJ to the drinking water of ICR mice had a positive effect on the growth performance and the intestinal and fecal microflora.

Keywords

Acknowledgement

This research was supported by "Regional Innovation Strategy (RIS)" through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (MOE) (2021RIS-001).

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