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Antibacterial Effects of Silver Fluoride and Difluorosilane-based Varnish on Streptococcus mutans

불화은과 다이플루오르실란 함유 바니쉬의 Streptococcus mutans에 대한 항균 효과

  • Hyunseok, Lee (Department of Pediatric Dentistry, College of Dentistry, Wonkwang University) ;
  • Soyoun, An (Department of Pediatric Dentistry, College of Dentistry, Wonkwang University)
  • 이현석 (원광대학교 치과대학 소아치과학교실) ;
  • 안소연 (원광대학교 치과대학 소아치과학교실)
  • Received : 2022.09.20
  • Accepted : 2022.11.04
  • Published : 2022.11.30

Abstract

The purpose of this study is to evaluate the antibacterial effects of two liquid fluoride materials on Streptococcus mutans (S. mutans). Riva star aquaTM (SDI, Bayswater, Australia), which consists of silver fluoride (AgF, step 1) and potassium iodide (KI, step 2), and Fluor protector® (FP; Ivoclar Vivadent, Liechtenstein) were used for experimental groups. Experimental groups were divided into 4 groups : AgF, KI, AgF + KI and FP. For the positive control (PC) group, ampicillin was used, and the negative control group (NC) did not receive any additional treatment. Each group was divided into 30 and 50 µL groups by volume of liquid and applied to flat-coated S. mutans. The diameter of the zone of inhibition was measured. The PC and AgF groups showed larger diameters than other materials (p < 0.05), and the AgF group showed no significant difference from the PC group in the 50 µL group (p > 0.05). The FP group showed larger diameters than the AgF + KI group in the 30 µL (p = 0.009). The KI group did not show significant difference from the NC group (p > 0.05). AgF is comparable to ampicillin in antibacterial effects on S. mutans, and better than FP.

연구의 목적은 2종의 액상형 불소 제재의 Streptococcus mutans에 대한 항균 효과를 평가하는 것이다. 불화은(AgF, 1제)과 요오드화칼륨(KI, 2제)로 구성된 Riva star aquaTM (SDI)와 Fluor protector® (FP; Ivoclar Vivadent)를 실험군에 사용하였다. 실험군은 4개의 군으로 구분하였다: AgF, KI, AgF + KI, FP. 양성 대조군(PC)에는 ampicillin을 사용하였고, 음성 대조군(NC)에는 아무런 처치도 시행하지 않았다. 각 군을 사용한 용액의 양에 따라 30과 50 µL로 다시 분류하였고, 평판 도말된 S. mutans에 적용하였다. 이후 억제대의 직경을 측정하였다. PC와 AgF는 모든 재료에 비해 큰 직경을 보였고(p < 0.05), AgF는 50 µL군에서 PC와 유의한 차이가 없었다(p > 0.05). FP는 30 µL군에서 AgF + KI 보다 큰 직경을 보였다(p = 0.009). KI는 NC와 유의한 차이가 없었다(p > 0.05). 불화은은 S. mutans에 대해 ampicillin과 유사한 항균효과를 보였으며, FP보다 더 뛰어남을 확인 하였다.

Keywords

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