대한소아치과학회지 (Journal of the korean academy of Pediatric Dentistry)

  • 제49권4호
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  • Pages.379-391
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  • 2022
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  • 1226-8496(pISSN)
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  • 2288-3819(eISSN)
대한소아치과학회 (Korean Academy of Pediatric Dentistry)
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Premixed MTA제재의 pH, 이온 유리 정도, 용해도

pH, Ion Release Capability, and Solubility Value of Premixed Mineral Trioxide Aggregates

  • 백설아 (단국대학교 치과대학 소아치과학교실) ;
  • 장유지 (단국대학교 치과대학 소아치과학교실) ;
  • 이정환 (단국대학교 치과대학 생체재료학교실) ;
  • 이준행 (단국대학교 치과대학 소아치과학교실) ;
  • 신지선 (단국대학교 치과대학 소아치과학교실) ;
  • 김종빈 (단국대학교 치과대학 소아치과학교실) ;
  • 한미란 (단국대학교 치과대학 소아치과학교실) ;
  • 김종수 (단국대학교 치과대학 소아치과학교실)
  • Seolah, Back (Department of Pediatric Dentistry, College of Dentistry, Dankook University) ;
  • YuJi, Jang (Department of Pediatric Dentistry, College of Dentistry, Dankook University) ;
  • Junghwan, Lee (Department of Biomaterials Science, College of Dentistry, Dankook University) ;
  • Joonhaeng, Lee (Department of Pediatric Dentistry, College of Dentistry, Dankook University) ;
  • Jisun, Shin (Department of Pediatric Dentistry, College of Dentistry, Dankook University) ;
  • Jongbin, Kim (Department of Pediatric Dentistry, College of Dentistry, Dankook University) ;
  • Miran, Han (Department of Pediatric Dentistry, College of Dentistry, Dankook University) ;
  • JongSoo, Kim (Department of Pediatric Dentistry, College of Dentistry, Dankook University)
  • 투고 : 2022.06.10
  • 심사 : 2022.09.01
  • 발행 : 2022.11.30
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초록

이 연구는 premixed MTA 제재와 기존 치수복조제의 경화 전, 후의 pH 값 그리고 칼슘, 황, 스트론튬 이온의 유리량, 용해도를 비교했다. 사용된 재료는 다음과 같다 : 레진 강화형 칼슘실리케이트(TheraCal LC®; TLC), 레진 강화형 수산화칼슘(UBP, Ultra-BlendTM plus), 2종류의 premixed MTA(Endocem MTA® premixed regular [EMPR] and Well-RootTM PT [WRP]). 각 재료의 시편은 경화 전, 경화 후 2군으로 나누어 준비한 뒤 증류수에 보관하였다. pH, 용해도를 측정하였으며 ICP-AES를 이용한 칼슘, 황, 스트론튬의 3가지 이온 유리량을 측정하였다. 경화 후 군에서 TLC와 UBP의 pH 값은 감소했다. 그러나 premixed MTA 재료의 pH 값은 증가했다. TLC는 다른 재료와 비교하여 스트론튬 이온 유리량이 더 많았다. 동시에 EMPR에서 황이온 유리량이 높았다(p < 0.05). 경화 후 군에서 칼슘 이온 방출은 두 종류의 premixed MTA에서 더 높았다(p < 0.05). 경화 후 군에서 용해도는 Kruskal-Wallis 서 test를 이용하여 통계분석하였고 Mann-Whitney U test를 이용하여 사후검정하였다. 결론적으로 레진 강화형 칼슘 실리케이트 시멘트, 레진 강화형 수산화칼슘 시멘트, 2종류의 premixed MTAs 모두 경화 후 알칼리성 pH 값과 낮은 용해도를 가지고 있었으며 다양한 이온을 유리했다.

The current study aimed to compare the pH, solubility value, and ion release capability of premixed mineral trioxide aggregates (MTAs) versus conventional pulp capping materials before and after setting. The following materials were used: resin-modified calcium silicate cement (TheraCal LC®, TLC), resin-modified calcium hydroxide cement (Ultra-BlendTM plus, UBP), and 2 kinds of premixed MTA (Endocem MTA® premixed regular [EMPR] and Well-RootTM PT [WRP]). The specimens of each material were prepared before and after setting and were immersed in distilled water. The materials' pH and solubility value were assessed. Next, three kinds of ion (calcium, sulfide, and strontium) released by pulp capping materials were evaluated via inductively coupled plasma atomic emission spectrometry. In the after-setting group, the pH of TLC and UBP decreased. However, the pH of the premixed MTAs increased with time. TLC released a higher concentration of strontium ion compared with the other materials. Meanwhile, EMPR released a significantly high concentration of sulfide ion (p < 0.05). In the after-setting group, the 2 kinds of premixed MTAs released a significantly higher concentration of calcium ion compared with the other materials (p < 0.05). In the after-setting group, EMPR had a significantly low solubility value (p < 0.05). The Kruskal-Wallis test, followed by the Mann-Whitney U test with Bonferroni correction, was used in statistical analysis. In conclusion, resin-modified calcium silicate cement, modified calcium hydroxide cement, and the 2 kinds of premixed MTAs had an alkaline pH and low solubility value and they released various concentrations of ions after setting.

키워드

과제정보

This study was supported through the Research-Focused Department Promotion Project as a part of the University Innovation Support Program for Dankook University in 2021.

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