The Korean Journal of Food And Nutrition (한국식품영양학회지)

The Korean Society of Food and Nutrition (한국식품영양학회)
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Antioxidant Activities of Korean Perilla Leaves (Perilla frutescens) by Various Cultivars

잎들깨 품종에 따른 추출물의 항산화 활성 및 생리활성 평가

  • Hyun Young, Kim (Division of Crop Foundation, National Institute of Crop Science, Rural Development Administration) ;
  • HanGyeol, Lee (Division of Life Sciences, Jeonbuk National University) ;
  • Hye Young, Seo (Division of Crop Foundation, National Institute of Crop Science, Rural Development Administration) ;
  • Woo Duck, Seo (Division of Crop Foundation, National Institute of Crop Science, Rural Development Administration) ;
  • Mi Ja, Lee (Division of Crop Foundation, National Institute of Crop Science, Rural Development Administration) ;
  • Seung-Yeob, Song (Division of Crop Foundation, National Institute of Crop Science, Rural Development Administration) ;
  • Jung In, Kim (Dept. of Southern Area Crop Science, National Institute of Crop Science, Rural Development Administration) ;
  • June-Yeol, Choi (Division of Crop Foundation, National Institute of Crop Science, Rural Development Administration)
  • 김현영 (농촌진흥청 국립식량과학원 작물기초기반과) ;
  • 이한결 (전북대학교 자연과학대학 생물학과) ;
  • 서혜영 (농촌진흥청 국립식량과학원 작물기초기반과) ;
  • 서우덕 (농촌진흥청 국립식량과학원 작물기초기반과) ;
  • 이미자 (농촌진흥청 국립식량과학원 작물기초기반과) ;
  • 송승엽 (농촌진흥청 국립식량과학원 작물기초기반과) ;
  • 김정인 (농촌진흥청 국립식량과학원 남부작물부 밭작물개발과) ;
  • 최준열 (농촌진흥청 국립식량과학원 작물기초기반과)
  • Received : 2022.10.17
  • Accepted : 2022.11.14
  • Published : 2022.12.31
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Abstract

This study aimed to investigate the biological activities, including polyphenolic content, flavonoid content, and antioxidant activities, of various cultivars of Korean perilla leaves. The results indicated that among nine cultivars (Namcheon dlggae, Saedora, Nulbora, Donggel 1, Donggell 2, Soim, Sangyeop, Somirang, and Saebom) of perilla leaves, the total polyphenolic content (gallic acid equivalent mg/g, GAE) was the highest in "Nulbora," while it was lowest in Namcheon dlggae. Moreover, flavonoid content in the extracts of nine cultivars leaves was in the range of 132.93~268.50 mg catechin equivalent/g sample. The antioxidant effects of the perilla leaves were determined using two different in vitro bioassays measuring DPPH and ABTS radical-scavenging activities. The results revealed that antioxidant activity was also higher in "Nulbora" compared with other cultivars. Xanthin-oxidase-inhibition activity ranged from 65.65% to 80.58%, with "Nulbora" exhibiting the highest activity, although the difference with other cultivars was not significant. "Nulbora" extracts reduced the expression of pro-inflammatory genes and several cytokines, including IL-6 activation induced by LPS in macrophages in the range of 100-50 ㎍/mL. These results suggest that extracts from perilla leaves can be used as bioactive and functional materials that could be important in industrial applications in the future.

Keywords

Acknowledgement

본 연구결과는 농촌진흥청 연구사업(PJ016088032022) 및 농촌진흥청 학·연협동연구과정 지원사업에 의해 이루어진 것입니다.

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