International journal of advanced smart convergence

The Institute of Internet, Broadcasting and Communication (한국인터넷방송통신학회)
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Analysis of Lactate Dehydrogenase Levels of COVID-19 Patients in a Korean Hospital According to Sex and Age

  • Kim, Sun Gyu (Department of Medical Laser, Dankook University Graduate School of Medicine) ;
  • Song, Hee Seung (Department of Nursing, Sangji University) ;
  • Kim, Jae Kyung (Department of Biomedical Laboratory Science, Dankook University)
  • Received : 2022.11.27
  • Accepted : 2022.12.03
  • Published : 2022.12.31
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Abstract

This study aimed to determine whether lactate dehydrogenase (LDH) levels in coronavirus disease (COVID-19) patients in Korea were higher than those in patients without COVID-19, and the effect of sex and age on LDH levels. A retrospective, observational study was conducted to measure LDH levels in 247 and 225 female and male COVID-19 patients, respectively, who were admitted to the study hospital between April 1 and October 30, 2020. Serum LDH levels were measured using an automated analyzer. Results: LDH levels were elevated in both male and female patients with COVID-19. Among patients with COVID-19, LDH levels were higher in males than in females, and LDH levels were higher in patients with COVID-19 than in patients in the control group. In the analysis of differences in LDH levels by age, LDH levels in patients with COVID-19 increased statistically significantly with age in males and females (males: p=0.001, females: p=0.001). By examining the differences in LDH levels according to sex and age, this study contributed to the basic biochemical data available in Korea, particularly regarding patients with COVID-19. Further research may be needed to examine confounding variables.

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