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Updates on the coronavirus disease 2019 vaccine and consideration in children

  • Kang, Hyun Mi (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
  • Choi, Eun Hwa (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Kim, Yae-Jean (Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • Received : 2021.05.21
  • Accepted : 2021.06.03
  • Published : 2021.07.15

Abstract

Humanity has been suffering from the global severe acute respiratory syndrome coronavirus 2 pandemic that began late in 2019. In 2020, for the first time in history, new vaccine platforms-including mRNA vaccines and viral vector-based DNA vaccines-have been given emergency use authorization, leading to mass vaccinations. The purpose of this article is to review the currently most widely used coronavirus disease 2019 vaccines, investigate their immunogenicity and efficacy data, and analyze the vaccine safety profiles that have been published, to date.

Keywords

Acknowledgement

We would like to express our gratitude to Kyung-Ran Kim, Doo Ri Kim, Ye-Ji Kim, and Hwanhee Park for reviewing the data of the studies described in this manuscript.

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