Neonatal Medicine

  • 제28권3호
  • /
  • Pages.139-142
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  • 2021
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  • 2287-9412(pISSN)
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  • 2287-9803(eISSN)
대한신생아학회 (The Korean Society of Neonatology)
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Macrophage Activation Syndrome Presented in a Case of Neonatal Lupus

  • Kang, Chang Min (Department of Pediatrics, Korea University Guro Hospital, Korea University College of Medicine) ;
  • Choi, Jinwha (Department of Pediatrics, Korea University Guro Hospital, Korea University College of Medicine) ;
  • Lee, JungHwa (Department of Pediatrics, Korea University Guro Hospital, Korea University College of Medicine)
  • 투고 : 2021.06.28
  • 심사 : 2021.08.10
  • 발행 : 2021.08.31
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초록

Macrophage activation syndrome (MAS) is a potentially life-threatening complication in many autoimmune diseases. Early recognition and intervention are essential for a favorable outcome. Neonatal lupus, an acquired autoimmune disease in neonates caused by the transplacental passage of maternal autoantibodies, is rare and usually self-limited. Herein, we report a case of MAS in a patient with neonatal lupus, which improved with intravenous immunoglobulin.

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참고문헌

  1. Hon KL, Leung AK. Neonatal lupus erythematosus. Autoimmune Dis 2012;2012:301274. https://doi.org/10.1155/2012/301274
  2. Alongi A, Naddei R, De Miglio L, Natoli V, Ravelli A. Macrophage activation syndrome in pediatrics. Pediatr Allergy Immunol 2020;31 Suppl 24:13-5. https://doi.org/10.1111/pai.13158
  3. Heijstek V, Habib M, van der Palen R, van Doorn R, Muller PH. Macrophage activation syndrome in a newborn: report of a case associated with neonatal lupus erythematosus and a summary of the literature. Pediatr Rheumatol Online J 2021;19:13. https://doi.org/10.1186/s12969-021-00500-w
  4. Izmirly PM, Saxena A, Kim MY, Wang D, Sahl SK, Llanos C, et al. Maternal and fetal factors associated with mortality and morbidity in a multi-racial/ethnic registry of anti-SSA/Ro-associated cardiac neonatal lupus. Circulation 2011;124:1927-35. https://doi.org/10.1161/CIRCULATIONAHA.111.033894
  5. Fukaya S, Yasuda S, Hashimoto T, Oku K, Kataoka H, Horita T, et al. Clinical features of haemophagocytic syndrome in patients with systemic autoimmune diseases: analysis of 30 cases. Rheumatology (Oxford) 2008;47:1686-9 https://doi.org/10.1093/rheumatology/ken342
  6. Ahn SS, Yoo BW, Jung SM, Lee SW, Park YB, Song JJ. Application of the 2016 EULAR/ACR/PRINTO classification criteria for macrophage activation syndrome in patients with adult-onset still disease. J Rheumatol 2017;44:996-1003. https://doi.org/10.3899/jrheum.161286
  7. Borgia RE, Gerstein M, Levy DM, Silverman ED, Hiraki LT. Features, treatment, and outcomes of macrophage activation syndrome in childhood-onset systemic lupus erythematosus. Arthritis Rheumatol 2018;70:616-24. https://doi.org/10.1002/art.40417
  8. Han SB, Lee SY, Jeong DC, Kang JH. Should 2016 criteria for macrophage activation syndrome be applied in children with Kawasaki disease, as well as with systemic-onset juvenile idiopathic arthritis? Ann Rheum Dis 2016;75:e44. https://doi.org/10.1136/annrheumdis-2016-209395
  9. Ravelli A, Minoia F, Davi S, Horne A, Bovis F, Pistorio A, et al. 2016 Classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Collaborative Initiative. Arthritis Rheumatol 2016; 68:566-76. https://doi.org/10.1002/art.39332
  10. Parodi A, Davi S, Pringe AB, Pistorio A, Ruperto N, Magni-Manzoni S, et al. Macrophage activation syndrome in juvenile systemic lupus erythematosus: a multinational multicenter study of thirty-eight patients. Arthritis Rheum 2009;60:3388-99. https://doi.org/10.1002/art.24883
  11. Suzuki Y, Takahashi N, Yada Y, Koike Y, Matano M, Nishimura H, et al. Hemophagocytic lymphohistiocytosis in a newborn infant born to a mother with Sjogren syndrome antibodies. J Perinatol 2013;33:569-71. https://doi.org/10.1038/jp.2012.147
  12. Shimozawa H, Kono Y, Matano M, Suzuki Y, Koike Y, Yada Y, et al. Cytokine profile in two siblings with neonatal lupus erythematosus. Pediatr Int 2015;57:1211-4. https://doi.org/10.1111/ped.12723
  13. Park JH, Kim SH, Kim HJ, Lee SJ, Jeong DC, Kim SY. Macrophage activation syndrome in a newborn infant born to a mother with autoimmune disease. J Perinatol 2015;35:158-60. https://doi.org/10.1038/jp.2014.207