한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제38권5호
  • /
  • Pages.221-224
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  • 2021
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  • 1598-298X(pISSN)
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  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
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Testosterone/Estradiol Ratio in a Dog with Sertoli Cell Tumor-Seminoma Combination

  • Song, Doo-Won (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Lee, Chang-Min (Department of Veterinary Internal Medicine, College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University) ;
  • Kim, Seung-Gon (Chungdam Animal Hospital) ;
  • Kang, Min-Hee (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Kim, Dong-Wook (Cheonan Animal Medical Center) ;
  • Kim, Hwi-Yool (Department of Veterinary Surgery, College of Veterinary Medicine, Konkuk University) ;
  • Eom, Kidong (Department of Veterinary Radiology, College of Veterinary Medicine, Konkuk University) ;
  • Park, Hee-Myung (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
  • 투고 : 2021.07.08
  • 심사 : 2021.08.26
  • 발행 : 2021.10.31
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초록

A 8-year-old male Golden Retriever dog with bilateral cryptorchidism presented for evaluation of symmetric alopecia and gynecomastia. Abdominal radiography and computed tomography revealed bilateral enlargement of the testicles in the abdominal cavity. The concentrations of estradiol and testosterone in the blood were evaluated, and the results revealed a low testosterone/estradiol ratio despite a normal concentration of estradiol. For correction, cryptorchid testicles were surgically removed. Grossly, the bilateral retroperitoneal cryptorchid testicles were enlarged, firm, and spherical. On histopathologic examination, the right abdominal cryptorchid testicle was diagnosed as a Sertoli cell tumor (SCT)-Seminoma (SEM) combination. The contralateral testicle in the abdomen was diagnosed as a Sertoli cell tumor. The clinical signs of feminization were improved after surgery. To our knowledge, this is the first report of a case of simultaneous SCT on one side and SCT-SEM combination on the other side with sex hormone profiles in a dog.

키워드

과제정보

The authors thank IDEXX Laboratories (Westbrook, Maine, USA) for the histopathology services.

참고문헌

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