대한소아치과학회지 (Journal of the korean academy of Pediatric Dentistry)

  • 제48권3호
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  • Pages.359-366
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  • 2021
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  • 1226-8496(pISSN)
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  • 2288-3819(eISSN)
대한소아치과학회 (Korean Academy of Pediatric Dentistry)
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포도당-6-인산탈수소효소 결핍증 환아의 치과적 관리

Dental Management in a Child Patient with Glucose-6-phosphate Dehydrogenase Deficiency : A Case Report

  • 전지윤 (전남대학교 치의학전문대학원 소아치과학교실) ;
  • 양선미 (전남대학교 치의학전문대학원 소아치과학교실) ;
  • 최남기 (전남대학교 치의학전문대학원 소아치과학교실) ;
  • 김선미 (전남대학교 치의학전문대학원 소아치과학교실)
  • Jeon, Jiyoon (Department of Pediatric Dentistry, School of Dentistry, Chonnam National University) ;
  • Yang, Sunmi (Department of Pediatric Dentistry, School of Dentistry, Chonnam National University) ;
  • Choi, Namki (Department of Pediatric Dentistry, School of Dentistry, Chonnam National University) ;
  • Kim, Seonmi (Department of Pediatric Dentistry, School of Dentistry, Chonnam National University)
  • 투고 : 2021.05.25
  • 심사 : 2021.07.01
  • 발행 : 2021.08.31
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초록

포도당-6-인산탈수소효소 결핍증은 X 염색체 열성으로 유전되는 세계에서 가장 흔한 효소 결핍증이다. 이 질환은 우리나라에서는 드물게 나타나지만, 다문화 가정의 증가로 유병률이 높아질 가능성이 있다. 이 결핍증의 주된 문제는 소아치과에서 일반적으로 사용되거나 처방되는 일부 약물에 의해 용혈성 빈혈이 유발될 수 있다는 점이다. 소아치과 의사는 환자의 병력에 대한 정확한 지식을 갖고 용혈을 유발할 수 있는 산화 스트레스를 피하기 위해 소아 혈액 전문의와 상담해야 한다. 가장 효과적인 치료는 빈혈을 유발할 수 있는 인자에 노출되지 않도록 예방하는 것이다. 이 질환으로 진단받은 환자들에게 위험인자에 대한 적절한 교육은 필수적이다. 이 증례보고는 G6PD 결핍증 환아에서 주의해야 할 약물과 치과적 관리 방법에 대해 논의하고자 하였다.

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked recessive disorder and is the most common enzyme deficiency worldwide. Although this disease is rare in Korea, its prevalence may increase due to an increase of multicultural families. Patients with this deficiency are prone to hemolytic anemia provoked by specific drugs commonly used or prescribed in pediatric dentistry. It is necessary for pediatric dentists to have accurate knowledge of a patient's medical history and to consult with a pediatric hematologist to avoid oxidative stress that can lead to hemolysis. The most effective treatment is prevention of exposure to factors that may trigger anemia. Appropriate education regarding risk factors is essential for patients diagnosed with this disease. This case report aimed to discuss the drugs and dental management methods that should be cautious in children with G6PD deficiency.

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