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Suspected bradycardia due to interactions between HIV protease inhibitors and lidocaine: a case report

  • Hamaya, Eri (Department of Dental Anesthesiology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University) ;
  • Kamekura, Nobuhito (Department of Dental Anesthesiology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University) ;
  • Fujisawa, Toshiaki (Department of Dental Anesthesiology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University)
  • Received : 2021.09.01
  • Accepted : 2021.09.06
  • Published : 2021.10.01

Abstract

Keywords

References

  1. Torp KD, Metheny E, Simon LV. Lidocaine Toxicity. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan. Available from https://www.ncbi.nlm.nih.gov/books/NBK482479/
  2. Michalets EL. Update: clinically significant cytochrome P-450 drug interactions. Pharmacotherapy 1998; 18: 84-112. https://doi.org/10.1002/j.1875-9114.1998.tb03830.x
  3. Kikuchi Y, Genka I, Ishizaki A, Sunagawa K, Yasuoka A, Oka S. Serious bradyarrhythmia that was possibly induced by lopinavir-ritonavir in 2 patients with acquired immunodeficiency syndrome. Clin Infect Dis 2002; 15: 488-90.
  4. Heravi AS, Etzkorn LH, Urbanek JK, Crainiceanu CM, Punjabi NM, Ashikaga H, et al. HIV infection is associated with variability in ventricular repolarization: The multicenter AIDS cohort study (MACS). Circulation 2020; 141: 176-87. https://doi.org/10.1161/CIRCULATIONAHA.119.043042
  5. Narla VA. Sudden cardiac death in HIV-infected patients: a contemporary review. Clin Cardiol 2021; 44: 316-21. https://doi.org/10.1002/clc.23568