Journal of Pharmacopuncture (대한약침학회지)

KOREAN PHARMACOPUNCTURE INSTITUTE (대한약침학회)
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Network Analysis on Herbal Formulas from Wenrejingwei and Shang Han Lun

  • Kim, Anna (KM Data Division, Korea Institute of Oriental Medicine) ;
  • Kim, Sang-Hyun (KM Data Division, Korea Institute of Oriental Medicine) ;
  • Oh, Yong-Taek (Department of Diagnostics, College of Korean Medicine, Woosuk University)
  • Received : 2021.06.25
  • Accepted : 2021.08.02
  • Published : 2021.09.30
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Abstract

Objectives: This study aims to describe the utilization of herbal formulas from Wenrejingwei by using network analysis and understand the treatment of acute exogenous febrile diseases. Methods: We constructed a matrix of high-frequency herbal combinations (HCs) from Wenrejingwei and Shang Han Lun and cluster networks based on cohesive analysis. Network analysis was performed to compare the results. Results: The results of the high-frequency HC network in Wenrejingwei showed cohesive patterns in three categories corresponding to dampness-heat and warm-fever treatment. Compared to the Shang Han Lun network, the Wenrejingwei network indicated a careful approach in the use of pungent and warm herbs such as Guizhitang. Moreover, the combination of Scutellaria baicalensis and Coptis chinensis along with the use of herbs strengthening yin, such as Ginseng Radix and Liriopes Radix, provide evidence of a holistic approach in the treatment of exogenous febrile diseases by considering the balance of the human body damaged by heat. Conclusion: The results of this study could help select appropriate herbal formulas and treatment methods for treating Onbyeong and modern acute febrile infectious diseases.

Keywords

Acknowledgement

This work was supported by a National Research Foundation (NRF) grant funded by the Korea government (MSIP) (No. 2017R1C1B5018236) and the Korea Institute of Oriental Medicine (grant number KSN2013110).

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