한국동물생명공학회지 (Journal of Animal Reproduction and Biotechnology)

  • 제36권3호
  • /
  • Pages.129-136
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  • 2021
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  • 2671-4639(pISSN)
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  • 2671-4663(eISSN)
한국동물생명공학회 (The Korean Society of Animal Reproduction and Biotechnology)
권호 표지
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Investigation of single nucleotide polymorphism in TSH-β and CaSR associated with body weight in Korean native chickens (Gray Brown)

  • Oh, Dongyep (Gyeongsangbuk-Do Livestock Research institute) ;
  • Ha, Jae Jung (Gyeongsangbuk-Do Livestock Research institute) ;
  • Yi, Jun Koo (Gyeongsangbuk-Do Livestock Research institute) ;
  • Kim, Dae Hyun (Gyeongsangbuk-Do Livestock Research institute) ;
  • Oh, Seung Min (Gyeongsangbuk-Do Livestock Research institute) ;
  • Kim, Songmi (Center for Bio-Medical Engineering Core Facility, Dankook University) ;
  • Han, Kyudong (Center for Bio-Medical Engineering Core Facility, Dankook University) ;
  • Park, Yong-Soo (Korea National College of Agriculture and Fisheries)
  • 투고 : 2021.07.21
  • 심사 : 2021.08.30
  • 발행 : 2021.09.30
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초록

This study identified single nucleotide polymorphisms (SNPs) that affect the body weight of chickens. Analysis of body weight showed that the Cornish breed had the highest body weight, and the Korean native chicken (Gray Brown) had the lowest body weight. TSH is composed of an α-subunit and a β-subunit, and the TSH-β gene encoding the β-subunit has been reported to be associated with obesity. In chickens, it is located on chromosome 26 and is reported to be associated with growth. The calcium-sensing receptor gene (CaSR) plays a role in the regulation of extracellular calcium homeostasis and is responsible for calcium absorption in the urinary tract, which affects the eggshell quality in poultry. It was shown that TSH-β was strongly correlated with weight in Cornish and Korean native (Gray Brown) chickens, particularly in those with the CC trait. However, CaSR showed no association with body weight in poultry; it was associated with calcium and the eggshell. Thus, selection for TSH-β can be used to produce individuals with more favorable traits in terms of body weight.

키워드

과제정보

This study was performed with the support of the Cooperative Research Program for Agriculture Science & Technology Development (Project No. PJ015996012021), Rural Development Administration, Republic of Korea.

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