Acknowledgement
We would like to acknowledge the veterinarians who collected the infected samples and the contribution of all authors for this study.
References
- Lee C. Porcine epidemic diarrhea virus: an emerging and re-emerging epizootic swine virus. Virol J 2015;12:193. https://doi.org/10.1186/s12985-015-0421-2
- Song D, Park B. Porcine epidemic diarrhoea virus: a comprehensive review of molecular epidemiology, diagnosis, and vaccines. Virus Genes 2012;44:167-175. https://doi.org/10.1007/s11262-012-0713-1
- Diel DG, Lawson S, Okda F, Singrey A, Clement T, Fernandes MHV, Christopher-Hennings J, Nelson EA. Porcine epidemic diarrhea virus: an overview of current virological and serological diagnostic methods. Virus Res 2016;226:60-70. https://doi.org/10.1016/j.virusres.2016.05.013
- Chen Q, Li G, Stasko J, Thomas JT, Stensland WR, Pillatzki AE, Gauger PC, Schwartz KJ, Madson D, Yoon KJ, Stevenson GW, Burrough ER, Harmon KM, Main RG, Zhang J. Isolation and characterization of porcine epidemic diarrhea viruses associated with the 2013 disease outbreak among swine in the United States. J Clin Microbiol 2014;52:234-243. https://doi.org/10.1128/JCM.02820-13
- Chang SH, Bae JL, Kang TJ, Kim J, Chung GH, Lim CW, Laude H, Yang MS, Jang YS. Identification of the epitope region capable of inducing neutralizing antibodies against the porcine epidemic diarrhea virus. Mol Cells 2002;14:295-299.
- Sun DB, Feng L, Shi HY, Chen JF, Liu SW, Chen HY, Wang YF. Spike protein region (aa 636789) of porcine epidemic diarrhea virus is essential for induction of neutralizing antibodies. Acta Virol 2007;51:149-156.
- Sun J, Li Q, Shao C, Ma Y, He H, Jiang S, Zhou Y, Wu Y, Ba S, Shi L, Fang W, Wang X, Song H. Isolation and characterization of Chinese porcine epidemic diarrhea virus with novel mutations and deletions in the S gene. Vet Microbiol 2018;221:81-89. https://doi.org/10.1016/j.vetmic.2018.05.021
- Zhang X, Pan Y, Wang D, Tian X, Song Y, Cao Y. Identification and pathogenicity of a variant porcine epidemic diarrhea virus field strain with reduced virulence. Virol J 2015;12:88. https://doi.org/10.1186/s12985-015-0314-4
- Park JE, Kang KJ, Ryu JH, Park JY, Jang H, Sung DJ, Kang JG, Shin HJ. Porcine epidemic diarrhea vaccine evaluation using a newly isolated strain from Korea. Vet Microbiol 2018;221:19-26. https://doi.org/10.1016/j.vetmic.2018.05.012
- Lee S, Kim Y, Lee C. Isolation and characterization of a Korean porcine epidemic diarrhea virus strain KNU-141112. Virus Res 2015;208:215-224. https://doi.org/10.1016/j.virusres.2015.07.010
- Sun RQ, Cai RJ, Chen YQ, Liang PS, Chen DK, Song CX. Outbreak of porcine epidemic diarrhea in suckling piglets, China. Emerg Infect Dis 2012;18:161-163. https://doi.org/10.3201/eid1801.111259
- Wang L, Byrum B, Zhang Y. New variant of porcine epidemic diarrhea virus, United States, 2014. Emerg Infect Dis 2014;20:917-919. https://doi.org/10.3201/eid2005.140195
- Diep NV, Sueyoshi M, Izzati U, Fuke N, Teh APP, Lan NT, Yamaguchi R. Appearance of US-like porcine epidemic diarrhoea virus (PEDV) strains before US outbreaks and genetic heterogeneity of PEDVs collected in Northern Vietnam during 2012-2015. Transbound Emerg Dis 2018;65:e83-e93. https://doi.org/10.1111/tbed.12681
- Kim SH, Cho BH, Lee KY, Jang YS. N-terminal domain of the spike protein of porcine epidemic diarrhea virus as a new candidate molecule for a mucosal vaccine. Immune Netw 2018;18:e21. https://doi.org/10.4110/in.2018.18.e21