DOI QR코드

DOI QR Code

무세포 진피 기질을 활용한 재건 수술에 대한 문헌적 고찰

Use of Acellular Dermal Matrix in Reconstructive Surgery: A Review

  • 박지원 (제주대학교 의학전문대학원) ;
  • 채수욱 (청담유 성형외과) ;
  • 윤병민 (제주대학교병원 성형외과)
  • Ji Won Park (Jeju National University Graduate School of Medicine) ;
  • Soo Wook Chae (CHEONGDAM U Beauty Medical Center) ;
  • Byung Min Yun (Department of Plastic and Reconstructive Surgery, Jeju National University Hospital)
  • 투고 : 2021.10.28
  • 심사 : 2021.11.30
  • 발행 : 2021.12.30

초록

In recent decades, tissue engineering advances have led to more skin substitutes becoming available. Acellular dermal matrix, initially developed for use in the treatment of full-thickness burns, is made by removing the cellular components from the dermis collected from donated bodies or animals. This class of scaffold is used to replace skin and soft tissue deficiencies in a variety of fields, including breast reconstruction, abdominal wall reconstruction, and burn treatment. Herein, we provide a detailed review of the clinical applications of acellular dermal matrix.

키워드

참고문헌

  1. Han SK, You HJ. Wound coverage using advanced technology in Korea. J Korean Med Assoc 2011;54:594-603.
  2. Fosnot J, Kovach SJ 3rd, Serletti JM. Acellular dermal matrix: general principles for the plastic surgeon. Aesthet Surg J 2011;31(7 Suppl):5S-12S.
  3. Dai C, Shih S, Khachemoune A. Skin substitutes for acute and chronic wound healing: an updated review. J Dermatolog Treat 2020;31:639-48.
  4. Wainwright DJ. Use of an acellular allograft dermal matrix (AlloDerm) in the management of full-thickness burns. Burns 1995;21:243-8.
  5. Kim J, Lew DH, Roh TS, Lee WJ. Use of acellular allogenic dermal matrix (MegaDerm) in orbital wall reconstruction: a comparison with absorbable mesh plate and porous polyethylene. J Craniofac Surg 2017;28:e644-9.
  6. Kwon DJ, Lee YB, Ahn HC. Use of acellular allograft dermal matrix (AlloDerm®) and split-thickness skin graft for treatment of diabetic foot ulcer. J Kor Musculoskelet Transplant Soc 2007;7:86-91.
  7. Bohac M, Danisovic L, Koller J, Dragunova J, Varga I. What happens to an acellular dermal matrix after implantation in the human body? A histological and electron microscopic study. Eur J Histochem 2018;62:2873.
  8. Nahabedian MY. Acellular dermal matrices in primary breast reconstruction: principles, concepts, and indications. Plast Reconstr Surg 2012;130(5 Suppl 2):44S-53S.
  9. Ahn ST. Breast reconstruction using implants. J Korean Med Assoc 2011;54:51-60.
  10. JoAnna Nguyen T, Carey JN, Wong AK. Use of human acellular dermal matrix in implant- based breast reconstruction: evaluating the evidence. J Plast Reconstr Aesthet Surg 2011;64:1553-61.
  11. Janis JE, O'Neill AC, Ahmad J, Zhong T, Hofer SOP. Acellular dermal matrices in abdominal wall reconstruction: a systematic review of the current evidence. Plast Reconstr Surg 2012;130(5 Suppl 2):183S-193S.
  12. Choi EJ, Kim EK. Abdominal wall reconstruction with component separation. J Acute Care Surg 2018;8:43-50.
  13. Garvey PB, Giordano SA, Baumann DP, Liu J, Butler CE. Long-term outcomes after abdominal wall reconstruction with acellular dermal matrix. J Am Coll Surg 2017;224:341-50.
  14. Silverman RP. Acellular dermal matrix in abdominal wall reconstruction. Aesthet Surg J 2011;31(7 Suppl):24S-9S.