DOI QR코드

DOI QR Code

A Systematic Review and Meta Analysis of Randomized Controlled Trials of the Clinical Effect on Taking a Herbal Medicine on Postpartum Lactation

한약 복용이 산후 유즙분비에 미치는 효과에 대한 체계적 문헌고찰

  • Lee, Hye-Jung (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Lee, Su-Jeong (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Hwang, Deok-Sang (Dept. of Gynecology, College of Korean Medicine, Kyung Hee University) ;
  • Lee, Chang-Hoon (Dept. of Gynecology, College of Korean Medicine, Kyung Hee University) ;
  • Jang, Jun-Bock (Dept. of Gynecology, College of Korean Medicine, Kyung Hee University) ;
  • Lee, Jin-Moo (Dept. of Gynecology, College of Korean Medicine, Kyung Hee University)
  • 이혜정 (경희대학교 대학원 임상한의학과) ;
  • 이수정 (경희대학교 대학원 임상한의학과) ;
  • 황덕상 (경희대학교 한의과대학 부인과교실) ;
  • 이창훈 (경희대학교 한의과대학 부인과교실) ;
  • 장준복 (경희대학교 한의과대학 부인과교실) ;
  • 이진무 (경희대학교 한의과대학 부인과교실)
  • Received : 2021.07.16
  • Accepted : 2021.08.27
  • Published : 2021.08.27

Abstract

Objectives: The purpose of this study is to assess the effect of taking herbal medicine for the postpartum lactation. Methods: We searched 9 databases for recent three years, that contained four english, two chinese, one japanese and two korean database from September 17, 2016 to December 31, 2020. Randomized controlled trials (RCTs) were eligible. Measurement of outcome included total curative effective rate, volume of lactation, volume of milk supplement, and serum prolactin concentration. The risk of bias was assessed by two independent authors using the Cochrane risk of bias tool. Results: Total 725 of studies was screened, 11 RCTs were finally selected. Number of participants per study ranged from 60 to 257. The treatment group of taking a herbal medicine is effective for improving total curative effective rate, volume of lactation, volume of milk supplement, and serum prolactin concentration compared with control group. Because most of the studies had considerable heterogeneity in terms of type of intervention and comparison for outcome measurement, meta analysis for quantitative analysis was impossible. Conclusions: This studies showed that taking a herbal medicine is effective on increasing volume of lactation and speeding up the start of the first breastfeeding. However, included studies suffered from incomplete reporting, high or unclear risk of bias and substantial heterogeneity between studies. In the Future, further high-quality RCTs are needed to prove effectiveness of herbal medicine for breastfeeding and reduce the risk of bias.

Keywords

References

  1. Kim TH, et al. A clinical study on the effect of acupuncture treatment for the chage of milk production. J of obstet & Gync. 2007;20(4):74-86.
  2. World Health Organization 2018. Guideline: counselling of women to improve breastfeeding practices. World Health Organization. 2018:99-101. Available from:URL:https://www.who.int/publications/i/item/9789241550468
  3. Korean Ministry of Health and Welfare. 2018 Results of postpartum care survey [cited Dec 20, 2018]. Available from: URL:http://www.mohw.go.kr
  4. Korean committee for UNICEF. A survey of breatfeeding in korea. Seoul:Korean committee for UNICEF. 2016:17, 33.
  5. Qin WD, et al. Effects of precondition of acupoint embedding thread on enterokinesia and lactation in the post-cesarean parturient. Chinese Acupuncture & Moxibustion. 2007;27(6):417-20.
  6. Lee EH, Kim TH. Effects of Boheo-tang and Boheo-tang plus Cervi Pantotrichum Cornu : on Lactation in Postpartum mice. J of obstet & Gync. 2008;21(4):1-16.
  7. Kim DH, et al. Effects of Mokhyangsaenghwa-tang and Mokhyangsaenghwa-tang plus Cervi Pantotrichum Cornu on Recovery and Lactation. J of obstet & Gync. 2005;18(1):111-27.
  8. Lee SH, Kang HS. The effect of YongChunSan in the hypogalactia in a mouse. J of obstet & Gync. 1996;9(1):191-203.
  9. Park DS, et al. Effect of Jeoje and Tongyu-tang except Cheonsangap on lactation in postpartum rat. J of obstet & Gync. 2004;17(2):27-40.
  10. Moon YS, Bae JK. Influence of Malt on Lactation of the White Rat. J of obstet & Gync. 1994;7(1):1-12
  11. Lee GW, et al. Effect of Melandrii Herba, Akebia Quinata Decaisne, and Tetrapanax Papyriferus on Milk Secretion and Lactation Related Factors in Postpartum Mice. J of obstet & Gync. 2018;31(2):1-17
  12. Kim YJ, et al. The clinical effect on acupuncture treatment of postpartum hypogalactia: A systematic review of randomized controlled trials. The Society of Korean Medicine Obstetrics and Gynecology. 2017;30(3):79-91.
  13. Lee BR, et al. Review of Clinical Research on Effect of Herbal Medicine for Postpartum Hypogalactia. J of Korean Academy of Breastfeeding Medicine. 2016;2(1):27-42.
  14. Wang S, et al. Efficacy of chinese herbal medicine Zengru-Gao to promote breastfeeding: a multicenter randomized controlled trial. BMC Complement Altern Med. 2018;18(1):53. https://doi.org/10.1186/s12906-018-2121-0
  15. Han Y, Wei M. Observation on the curative effect of Chinese medicine combined with external application of Glauber's salt in the treatment of postpartum hypogalactia(中药联合芒硝外敷治疗产后缺乳的疗效观察). World Latest Medicine Information. 2018;18(105):176.
  16. Ouyang LF, et al. Effect of traditional Chinese medicine foot bath combined with prolactin stew on postpartum lactation. CJCM Zhongyi linchuang yanjiu(中医临床研究). 2018;10(36):75-7.
  17. Lu J, Ma CX, Li JN. Curative Effect Observation of Lactation Decoction Combined with Acupoint Massage on Postpartum Lactation. Clinical journal of traditional chinese medicine. 2018;30(8):1548-50.
  18. Lu YY, et al. Clinical study on the treatment of postpartum lactation insufficiency with prolactin decoction (催乳汤治疗产后乳汁不足临床研究). Shanxi zhongyi(陕西中医). 2018;39(2):241-2.
  19. Liu ZD. Effect investigation of Miru-Decoction combined with Carboprost Methylate suppositiorites on the lactation after cesarean section. Clinical Research JAN. 2018;26(1):176-7.
  20. Feng R. Effect of Yiqiyangxueshengru-decoction in treating postpartum lactation of qi and blood deficiency (益气养血生乳汤治疗气血亏虚型产后缺乳疗效分析). Electronic Journal Of Practical Gynecologic Endocrinology. 2019;6(26):40-1.
  21. Zhang Y. Treatment of 41 cases of deficiency of qi and blood with qi and Blood Decoction(中医推拿配合催乳汤治疗气血虚弱型缺乳41例). China's Naturopathy. 2019;27(2):53-5.
  22. Xi XW. Efficacy of oral prolactin decoction combined with shaoze point rubbing in treating postpartum lactation (催乳汤口服配合少泽穴揉按治疗产后缺乳的疗效). Gansu Science and Technology. 2019;35(23):101-3.
  23. Xu JF. The effect of traditional Chinese medicine breast-promoting soup combined with breast massage on postpartum lactation of parturients (中药促泌乳汤联合乳房按摩对产妇产后泌乳的影响). China Traditional Chinese Medicine Technology(中国中医药科技). 2020;27(6):925-6.
  24. Gao WL, Liao Q, Ma XH. Clinical Study of Treatment on Postpartum Hypogalactia after Cesarean Section by Acupoint Massage Combined with Prolactin Soup. J Med Res. 2020;49(3):162-5.
  25. The Society of Korean Medicine Obstetrics and Gynecology. Korean Medicine Obstetrics & Gynecology. 3rd edition. Seoul:Eui Seong Dang Publishing. 2016:833-8.
  26. Anderson L, et al. Effectiveness of breast massage for the treatment of women with breastfeeding problems: a systematic review. JBI Database of Systematic Reviews and Implementation Reports. 2019;17(8):1668-94. https://doi.org/10.11124/jbisrir-2017-003932
  27. Kim YH, Lee H, Yim YK. The trend of experimental study on the effect of acupuncture at ST36(Zusanli). The Korean J of Meridian & Acupoint. 2005;22(1):133-50.
  28. Kim TH, et al. A Clinical Study on the Effect of Acupuncture Treatment for the Change of Milk Production. J of obstet & Gync. 2007;20(4):74-86.
  29. Qin WD, Liu WJ, Gao SZ. Effects of precondition of acupoint embedding thread on-enterokinesia and lactation in the postcesarean parturient. Zhongguo Zhen Jiu. 2007;27(6):417-20.
  30. Lim YK, et al. Details of Meridians & Acupoint(Volume I). 5th edition. Gangwon-do:Yibang medicalbook center. 2010:259, 447, 1173.
  31. Kang K, et al. Correlation between Qi-Stagnation and pressure pain threshold on CV17 in burning mouth syndrome patients in the perspective of quantification of pressure pain threshold on CV17 by using algometer. Korean J Orient Int Med 2012;33(4):498-510.
  32. An BK. Introduction to Chinese Translation and Annotation of Medicine(國譯編註醫學入門). Seoul:Namsandang. 1996:119.
  33. The textbook compilation committee of Korean herbology. Korean herbology. Seoul:Younglimsa Publishing co. 2008.
  34. Byun JH. Complete Translation and Proofreading of Women's Remedies (完譯校註婦人良方大全). Seoul:Beobmun-books Publishing co. 2014.