The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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The Effect of Bojungikgi-tang on Stress Urinary Incontinence: A Systematic Review and Meta-Analysis

복압성 요실금에 대한 보중익기탕의 효과 : 체계적 문헌고찰과 메타분석

  • Nam, Hyun-seo (Dept. of Internal Medicine of Korean Medicine, Oriental Medicine Hospital of Sangji University) ;
  • Baek, Tae-hyun (Dept. of Internal Medicine of Korean Medicine, Oriental Medicine Hospital of Sangji University)
  • 남현서 (상지대학교부속한방병원 한방내과) ;
  • 백태현 (상지대학교부속한방병원 한방내과)
  • Received : 2021.05.17
  • Accepted : 2021.06.26
  • Published : 2021.06.30
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Abstract

Objectives: This study investigates the effects and safety of Bojungikgi-tang for stress urinary incontinence by systemic review and meta-analysis of randomized controlled trials (RCTs). Methods: RCTs were selected from articles published until December 2019 in seven domestic and foreign databases. The quality of the literature was evaluated using Cochrane's risk of bias (RoB) tool, and RevMan 5.3 was used to synthesize the results. Results: A total of 694 patients with stress urinary incontinence participated in eight RCTs. Meta-analysis showed that the total effective rate of treatment that combines pelvic floor muscle training (PFMT) and Bojungikgi-tang was significantly higher than that of PFMT alone. The volume of urine leakage per hour after the combined treatment was significantly lower than that of PFMT alone. The International Consultation on Insurance Questionnaire-Short Form (ICIQ-SF) scores from combining PFMT and Bojungikgi-tang were significantly lower than those for PFMT alone. Conclusion: This study suggests that Western medical treatment combined with Bojungikgi-tang for urinary incontinence from stress might be more effective in improving symptoms than conventional Western medical treatment alone. However, the number of studies included in the meta-analysis was insufficient, and the quality of the selected literature was generally low. Therefore, high-quality clinical studies on herbal medicine treatment for urinary incontinence would be required in the future.

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References

  1. Austin PF, Bauer SB, Bower W, Chase J, Franco I, Hoebeke P, Rittig S, et al. The standardization of terminology of lower urinary tract function in children and adolescents: Update report from the standardization committee of the International Children's Continence Society. Neurourology Urodynamics 2016;35(4):471-81. https://doi.org/10.1002/nau.22751
  2. Class of Internal Medicine of the kidney system in Korean Medical College. Internal Medicine of the kidney system. Seoul: Goonja; 2011, p. 24-9.
  3. Oh SJ, Park WH, Park CH, Paick JS, Seo JT, Lee YS, et al. Prevalence of Urinary Incontinence and Incontinence-related Quality of Life in Korean Women: A Population-based Study. J Korean Continence Society 2003;7:73-80. https://doi.org/10.5213/jkcs.2003.7.2.73
  4. Choi JB. Urinary Incontinence in Women. Korean Journal of Family Medicine Korean Journal of Family Medicine 2010;31(9):661-71. https://doi.org/10.4082/kjfm.2010.31.9.661
  5. Lim JH, Kim MK, Park YK. A Prospective Randomized Trial Comparing Transobturator Vaginal Tape and Tension Free Vaginal Tape Obturator Inside-Out for Surgical Treatment of Stress Incontinence. J Korean Continence Society 2005;9(2):82-7. https://doi.org/10.5213/jkcs.2005.9.2.82
  6. Jeong SY, Kim DI. Case report of the stress urinary incontinence which is improved by Acupunture treatment and Sasang Constitutional Herbal medication. The Journal of Korean obstetrics & gynecology 2007;20(4):210-6.
  7. Professors of Herbal Formula Science in Oriental Medical School. Herbal Formula Science. Seoul: Younglimsa; 1990, p. 279-82.
  8. Seo EB, Cho HB, Kim SB, Seo YJ, Choi CM, Lee JH. Literature Study about Oriental Medical Treatment on the Urinary Incontinence. Korean J Oriental Physiology & Pathology 2013;27(4): 374-82.
  9. Higgins JPT, Green S. Cochrane handbook for systematic reviews of interventions Ver 5.1.0 [updated Mar 2011]. The Cochrane Collaboration, 2011. Available from http://handbook.cochrane.org.
  10. Higgins JPT, Green S. Analyzing and presenting results. Cochrane handbook for systematic reviews of interventions 4.2.6. Chichester, UK: John Wiley&Sons Inc; 2008, p. 79-165.
  11. Zeng YJ, Zhao P, Chen YY, Zhuo WX, Tian AA, Liang SY. Clinical Observation on Efficacy of Modified Buzhong Yiqi Tang Combined with Pelvic floor muscle training in treating SUI. Journal of New Chinese medicine 2015;47(10):50-2.
  12. Li CN. Clinical Observation on Efficacy of Modified Buzhong Yiqi Tang Combined with Kegel exercises in treating Aged Female SUI. Contemporary Medical Symposium 2018;16(11):69-70.
  13. Zhao X, Liu LJ. Clinical Observation on Efficacy of Modified Buzhong Yiqi Tang Combined with Pelvic floor muscle training and Effect on Vaginal pressure and Urinary dynamic test in treating middle aged female patients with SUI. Modern Journal of Integrated Traditional Chinese and Western Medicine 2018;27(23):2559-61.
  14. Ma GP. 34 cases of Aged patients with stress incontinence treated by Modified Buzhong Yiqi Tang Combined with Oxybutynin Hydrochloride. Asia-Pacific Traditional Medicine 2012;8(10): 76-7.
  15. Zhang R. Efficacy of the Buzhong Yiqi decoction plus exercise of pelvic floor function on stress urinary incontinence after delivery. Clinical Study of Traditional Chinese Medicine 2018;10(7):113-4.
  16. Wang JH, Hong XS. 37 cases of 1st grade-stress urinary incontinence after treatment with Buzhong Yiqi decoction plus Biofeedback therapy. Hunan Journal of Traditional Chinese Medicine 2019; 35(3):53-4.
  17. Lin Y, Tang L. Clinical Study of the Treatment on 32 Cases Postpartum Stress Incontinence by Combined with Supplemented Middle-Tonifying Qi-Replenishing Decoction and Pelvic Floor Function Training. Journal of New Chinese Medicine 2011;43(4):58-9.
  18. Mei XF, Xia YG, Tian Y, Zhao J, Zhang C, Zeng WT. Clinical Observation of Modified Buzhong Yiqi Tang Combined with Kegel Exercises in Treating Female SUI. Journal of New Chinese Medicine 2017;49(8):64-6.
  19. Kim MH. A Study on the Investigation of Incontinence Conditions after Non-Operative Treatment of female patients with stress urinary incontinence. Ewha Womens Graduate school, National master 2002;13:81-9.
  20. Kim SJ, Park YS, Kim DC. A Study on the Improvement of Urinary Icontinence Symptoms in Patients with Acupuncture, Moxibustion and Magnetic Innervation Therapy. The Journal of Korean obstetrics & gynecology 2006;19(2):261-70.
  21. Swithinbank LV, Donovan JL, du Heaume JC, Rogers CA, James MC, Yang Q, et al. Urinary symptoms and incontinence in women: relationships between occurrence, age, and perceived impact. Br J Gen Pract 1999;49(448):897-900.
  22. Kim EK, Hwang DS, Lee JM, Lee CH, Jang JB, Lee KS. Investigation of Clinical Research of Acupuncture Treatment on Urinary Incontinence in Medline. The Journal of Korean obstetrics & gynecology 2013;26(2):166-77. https://doi.org/10.15204/jkobgy.2013.26.2.166
  23. Grimby A, Milsom I, Molander U, Wiklund I, Ekelund P. The influence of urinary incontinence on quality of life of elderly women. Age and Aging 1993;22(2):82-9. https://doi.org/10.1093/ageing/22.2.82
  24. Jeong EA, Oh SH, Cho SK, Bae IY. A Study on the Influence of pharmacoacupuncture on Patients with Incontinence after Menopause. The Journal of Korean obstetrics & gynecology 2003; 16(1):231-9.
  25. Kwon SW, Park JY, Chinese medicine internal medicine diagnostic guide for Oriental medicine clinician III. Goyang: Gaonhaemedia; 2017, p. 178-80.
  26. Jeon MJ, Bae SW, Kim SK. Current opinion of the treatment of female voiding dysfunction. Korean Journal of Obstetrics & Gynecology Science 2008;51(3):275-85.
  27. Lee KS, Lee YS. Pharmacological Therapy for Urinary Incontinence. J Korean Med Assoc 2007;50(11):1025-36. https://doi.org/10.5124/jkma.2007.50.11.1025
  28. Seo HJ, Kim SJ, Seok NJ, Kim JC, Lee JY, Lee DH. Causes of Reoperation after Midurethral Sling Procedures in Female Stress Urinary Incontinence. International Neurourology Journal 2006;10(1):55-9.
  29. Korean Obstetrics & Gynecology Science. Obstetrics 4th edition. Seoul: Goonja publishing company; 2010, p. 1081-105.
  30. Kim DI. A Study on the Diagnosis and Treatment of Stress Urinary Incontinence. The Journal of Korean obstetrics & gynecology 1999;12(2): 349-73.
  31. Lee SJ. Bonchogangmok 1. Seoul: MunSachul; 2008, p. 240.
  32. Hwang DY. Uijongsonik(sang). Seoul: Yeogang; 1993, p. 181.
  33. Seo MJ, Lee KB, Park JH, Hong SH. The Current Trend of Research about Bojungikki-tang. Korea Journal of Oriental Medicine 2010;16(2):83-90.
  34. Oh JA, Shin MR. A Case study of Urinary Disturbance Treated with Soeumin's Bojungikgi-tang. J Sasang Constitut Med 2013;25(4):396-405. https://doi.org/10.7730/JSCM.2013.25.4.396
  35. Park SH, Chae MS, Jang JB, Lee JM, Lee CH, Lee KS, et al. A Case Report of the Geriatric Stress Urinary Incontinence Patient Improved by Korean Medical Treatment. J Korean Obstet Gynecol 2014;27(4):133-40. https://doi.org/10.15204/jkobgy.2014.27.4.133