Journal of Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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In vitro biological activities of lotus (Nelumbo nucifera) leaves extract

연잎(Nelumbo nucifera) 추출물의 in vitro 생리활성

  • Park, Eun Jung (Department of Chemical Engineering, Chungwoon University) ;
  • Cho, Hye Won (Department of Chemical Engineering, Chungwoon University) ;
  • Park, Yu Jin (Department of Chemical Engineering, Chungwoon University) ;
  • In, Man-Jin (Department of Chemical Engineering, Chungwoon University) ;
  • Kim, Dong Chung (Department of Chemical Engineering, Chungwoon University)
  • Received : 2021.03.22
  • Accepted : 2021.04.19
  • Published : 2021.06.30
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Abstract

Antioxidative, anticoagulant, and α-glucosidase inhibitory effects of 60% (v/v) ethanolic extract from lotus (Nelumbo nucifera) leaves were investigated in vitro. The yield and polyphenol content of the lotus leaves extract were 35.3±1.1% and 186.2±5.2 ㎍ gallic acid equivalents/mg, respectively. The lotus leaves extract effectively scavenged free and cation radicals, and nitrite in a concentration-dependent manner, and possessed potent reducing power. The lotus leaves extract had remarkable anticoagulant and α-glucosidase inhibitory activities as a function of the extract concentration.

연잎(Nelumbo nucifera)의 60% (v/v) 에탄올 수용액 추출물의 항산화, 혈장 항응고 및 α-glucosidase 저해 효과를 in vitro에서 확인하였다. 연잎 추출물의 수율은 35.3±1.1%이었고, 폴리페놀 화합물 함량은 186.2±5.2 ㎍ gallic acid equivalents/mg으로 나타났다. 연잎 추출물은 농도에 비례하여 유리라디칼, 양이온라디칼 및 아질산염을 효과적으로 소거하였고 뛰어난 환원력을 보유하고 있었다. 또한 연잎 추출물은 농도 의존적으로 우수한 혈장 항응고 및 α-glucosidase 저해 활성을 나타내었다.

Keywords

Acknowledgement

본 논문은 제1저자의 청운대학교 석사학위논문을 바탕으로 작성되었습니다.

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