Journal of Environmental Health Sciences (한국환경보건학회지)

Korean Society of Environmental Health (한국환경보건학회)
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Comprehensive Review of Domestic and Foreign Biomonitoring Programs and Current Status of Bio-sample Application

국내외 바이오모니터링 프로그램 및 생체시료 활용 현황

  • Kim, Da Hae (Department of Integrative Bioscience & Biotechnology, Sejong University) ;
  • Kim, Sungkyoon (Department of Environmental Health Sciences, Seoul National University) ;
  • Lee, Seungho (Department of Occupational and Environmental Medicine, Ajou University School of Medicine) ;
  • Choi, Yoon-Hyeong (Department of Preventive Medicine, Gachon University) ;
  • Kim, Jin Hee (Department of Integrative Bioscience & Biotechnology, Sejong University)
  • 김다해 (세종대학교 바이오융합공학과) ;
  • 김성균 (서울대학교 보건대학원 환경보건학과) ;
  • 이승호 (아주대학교 의과대학 직업환경의학과) ;
  • 최윤형 (가천대학교 의과대학 예방의학교실) ;
  • 김진희 (세종대학교 바이오융합공학과)
  • Received : 2021.05.31
  • Accepted : 2021.06.20
  • Published : 2021.06.30
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Abstract

Objectives: Biomonitoring programs have been widely implemented in the field of environmental health, both in Korea and worldwide. Recently, it has been suggested that the storage, management, and utilization of biosamples collected from biomonitoring programs should be organized based on a biobank system. Therefore, we attempted to review the current status of representative biomonitoring programs and biobank systems that have been implemented in Korea and in other countries. Methods: We searched for bio-samples collected in domestic and foreign biomonitoring programs and their applications. For this, we referred to research papers, homepages hosted by biomonitoring programs, and project reports. We also checked information for biobanks related with biomonitoring programs, including the operating systems, facilities, technologies, and regulations of biobanks. Results: We summarized six domestic and 32 foreign biomonitoring programs. These biomonitoring programs collected bio-samples to determine the relationship between environmental chemicals and diseases. Domestically, bio-samples from KoNEHS, KorSEP, MOCEH, KoCHENS, and KorEHS-C were stored at -80℃ in a deep freezer at the National Institute of Environmental Research, while KNHANES samples were stored at Korea Biobank, which has a stabilized biobanking system with a well-established database. Nine foreign biomonitoring programs (JECS, China-NHBP, CKB, CHMS, NHANES, GerES, Germaan ESB, MoBa, and UK Biobank) were ongoing for large populations. Among them, CKB, GermanESB, and UK biobank have been maintained for at least 10 years with their own biomonitoring programs as well as advanced systems for the safe storage of bio-samples. Conclusion: Currently on-going biobanks have devoted considerable efforts to managing bio-samples for public purposes. The preceding domestic and foreign biomonitoring programs and biobanks will be great references for constructing biobank facilities and systems for environmental public health in Korea in the future.

Keywords

Acknowledgement

본 논문은 환경부 국립환경과학원 '국가 환경보건바이오뱅크 구축 및 운영 로드맵 마련(NIER-SP2019-310)'의 지원을 받아 수행되었습니다.

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