Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
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Breast Ultrasound Microvascular Imaging and Radiogenomics

  • Ah Young Park (Department of Radiology, Bundang CHA Medical Center, CHA University) ;
  • Bo Kyoung Seo (Department of Radiology, Korea University Ansan Hospital, Korea University College of Medicine) ;
  • Mi-Ryung Han (Division of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University)
  • Received : 2020.09.25
  • Accepted : 2020.12.10
  • Published : 2021.05.01
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Abstract

Microvascular ultrasound (US) techniques are advanced Doppler techniques that provide high sensitivity and spatial resolution for detailed visualization of low-flow vessels. Microvascular US imaging can be applied to breast lesion evaluation with or without US contrast agents. Microvascular US imaging without a contrast agent uses a sophisticated wall filtering system to selectively obtain low-flow Doppler signals from overlapped artifacts. Microvascular US imaging with second-generation contrast agents amplifies flow signals and makes them last longer, which facilitates hemodynamic evaluation of breast lesions. In this review article, we will introduce various microvascular US techniques, explain their clinical applications in breast cancer diagnosis and radiologic-histopathologic correlation, and provide a summary of a recent radiogenomic study using microvascular US.

Keywords

Acknowledgement

We thank Sarah Kwon of the ultrasound division of Canon Medical Systems Korea Co. Ltd. for her assistance with ultrasound physics.

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