Korean Journal of Radiology

  • 제22권3호
  • /
  • Pages.297-307
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  • 2021
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  • 1229-6929(pISSN)
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  • 2005-8330(eISSN)
대한영상의학회 (The Korean Society of Radiology)
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Comparison of Abbreviated MRI and Full Diagnostic MRI in Distinguishing between Benign and Malignant Lesions Detected by Breast MRI: A Multireader Study

  • Eun Sil Kim (Department of Radiology, Seoul National University Hospital) ;
  • Nariya Cho (Department of Radiology, Seoul National University Hospital) ;
  • Soo-Yeon Kim (Department of Radiology, Seoul National University Hospital) ;
  • Bo Ra Kwon (Department of Radiology, Seoul National University Hospital Healthcare System Gangnam Center) ;
  • Ann Yi (Department of Radiology, Seoul National University Hospital Healthcare System Gangnam Center) ;
  • Su Min Ha (Department of Radiology, Seoul National University Hospital) ;
  • Su Hyun Lee (Department of Radiology, Seoul National University Hospital) ;
  • Jung Min Chang (Department of Radiology, Seoul National University Hospital) ;
  • Woo Kyung Moon (Department of Radiology, Seoul National University Hospital)
  • 투고 : 2020.03.19
  • 심사 : 2020.09.14
  • 발행 : 2021.03.01
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초록

Objective: To compare the performance of simulated abbreviated breast MRI (AB-MRI) and full diagnostic (FD)-MRI in distinguishing between benign and malignant lesions detected by MRI and investigate the features of discrepant lesions of the two protocols. Materials and Methods: An AB-MRI set with single first postcontrast images was retrospectively obtained from an FD-MRI cohort of 111 lesions (34 malignant, 77 benign) detected by contralateral breast MRI in 111 women (mean age, 49.8. ± 9.8; range, 28-75 years) with recently diagnosed breast cancer. Five blinded readers independently classified the likelihood of malignancy using Breast Imaging Reporting and Data System assessments. McNemar tests and area under the receiver operating characteristic curve (AUC) analyses were performed. The imaging and pathologic features of the discrepant lesions of the two protocols were analyzed. Results: The sensitivity of AB-MRI for lesion characterization tended to be lower than that of FD-MRI for all readers (58.8-82.4% vs. 79.4-100%), although the findings of only two readers were significantly different (p < 0.05). The specificity of AB-MRI for lesion characterization was higher than that of FD-MRI for 80% of readers (39.0-74.0% vs. 19.5-45.5%, p ≤ 0.001). The AUC of AB-MRI was comparable to that of FD-MRI for all readers (p > 0.05). Fifteen percent (5/34) of the cancers were false-negatives on AB-MRI. More suspicious margins or internal enhancement on the delayed phase images were related to the discrepancies. Conclusion: The overall performance of AB-MRI was similar to that of FD-MRI in distinguishing between benign and malignant lesions. AB-MRI showed lower sensitivity and higher specificity than FD-MRI, as 15% of the cancers were misclassified compared to FD-MRI.

키워드

과제정보

This study has received funding by grant (no. 03-2019-0330) from the Seoul National University Hospital Research Fund.

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