Parasites, Hosts and Diseases

  • 제59권3호
  • /
  • Pages.291-296
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  • 2021
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  • 2982-5164(pISSN)
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  • 1738-0006(eISSN)
대한기생충학·열대의학회 (The Korea Society for Parasitology and Tropical Medicine)
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A Case of Human Hepatic Alveolar Echinococcosis Accompanied by Lung and Brain Metastases

  • Liu, Chuanchuan (Research Center for High Altitude Medicine, Qinghai University) ;
  • Fan, Haining (Qinghai University Affiliated Hospital) ;
  • Ge, Ri-li (Research Center for High Altitude Medicine, Qinghai University)
  • 투고 : 2020.10.28
  • 심사 : 2021.02.09
  • 발행 : 2021.06.30
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초록

Alveolar echinococcosis (AE) is considered as a fatal zoonosis caused by the larvae of Echinococcus multilocularis. The lungs and brain are the most common metastatic organs. We report a human case of hepatic alveolar echinococcosis accompanied by lung and brain metastasis. In particular, the patient had a history of tuberculosis and the lung lesions were easily misdiagnosed as lung abscesses. The lesions of liver and lung underwent radical resection and confirmed as alveolar echinococcosis by pathological examination. The patient had no surgical complications after operation and was discharged after symptomatic treatment. Unfortunately, the patient later developed multiple intracerebral AE metastases. We required the patient to take albendazole orally for life and follow up.

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과제정보

Project supports were provided by the Qinghai Provincial Natural Science Foundation (2020-ZJ-956Q) and the National key R & D projects (2017YFC0909900)

참고문헌

  1. Sade R, Kantarci M, Ogul H, Gundogdu B, Aydinli B. Differentiation between hepatic alveolar echinococcosis and primary hepatic malignancy with diffusion-weighted magnetic resonance imaging. Diagn Interv Imaging 2018; 99: 169-177. https://doi.org/10.1016/j.diii.2017.09.007
  2. Liu W, Delabrousse E, Blagosklonov O, Wang J, Zeng H, Jiang Y, Wang J, Qin Y, Vuitton DA, Wen H. Innovation in hepatic alveolar echinococcosis imaging: best use of old tools, and necessary evaluation of new ones. Parasite 2014; 21: 74. https://doi.org/10.1051/parasite/2014072
  3. Spahn S, Helmchen B, Zingg U. Alveolar echinococcosis of the right adrenal gland: a case report and review of the literature. J Med Case Rep 2016; 10: 325. https://doi.org/10.1186/s13256-016-1115-0
  4. Atalan G, Sivrioglu AK, Sonmez G, Celik M, Simsek B. A case of alveolar echinococcosis presenting as cerebral and spinal intradural metastases. Eurasian J Med 2016; 48: 149-152. https://doi.org/10.5152/eurasianjmed.2015.15003
  5. Salm LA, Lachenmayer A, Perrodin SF, Candinas D, Beldi G. Surgical treatment strategies for hepatic alveolar echinococcosis. Food Waterborne Parasitol 2019; 15: e00050. https://doi.org/10.1016/j.fawpar.2019.e00050
  6. Schmidberger J, Steinbach J, Schlingeloff P, Kratzer W, Gruner B. Surgery versus conservative drug therapy in alveolar echinococcosis patients in Germany-A health-related quality of life comparison. Food Waterborne Parasitol 2019; 16: e00057. https://doi.org/10.1016/j.fawpar.2019.e00057
  7. Kayacan SM, Vatansever S, Temiz S, Uslu B, Kayacan D, Akkaya V, Erk O, Saka B, Karadag A, Turkmen K, Fatih Y, Kerim G. Alveolar echinococcosis localized in the liver, lung and brain. Chin Med J (Engl) 2008; 121: 90-92. https://doi.org/10.1097/00029330-200801010-00018
  8. Kantarci M, Bayraktutan U, Pirimoglu B, Ogul H, Oral A, Eren S, Gundogdu B. Multisystem involvement of alveolar echinococcosis in a child. J Infect Dev Ctries 2014; 8: 1494-1497. https://doi.org/10.3855/jidc.4214
  9. Schmidberger J, Kratzer W, Stark K, Gruner B. Alveolar echinococcosis in Germany, 1992-2016. An update based on the newly established national AE database. Infection 2018; 46: 197-206. https://doi.org/10.1007/s15010-017-1094-0
  10. Wang H, Lu C, Liu X, Zhang W. Metastatic and prognostic factors in patients with alveolar echinococcosis. Int J Clin Exp Pathol 2015; 8: 11192-11198.
  11. McManus DP, Gray DJ, Zhang W, Yang Y. Diagnosis, treatment, and management of echinococcosis. BMJ 2012; 344: e3866. https://doi.org/10.1136/bmj.e3866
  12. Bresson-Hadni S, Delabrousse E, Blagosklonov O, Bartholomot B, Koch S, Miguet JP, Mantion GA, Vuitton DA. Imaging aspects and non-surgical interventional treatment in human alveolar echinococcosis. Parasitol Int 2006; 55 (suppl): 267-272. https://doi.org/10.1016/j.parint.2005.11.053
  13. Sulima M, Nahorski W, Gorycki T, Wolyniec W, Waz P, Felczak-Korzybska I, Szostakowska B, Sikorska K. Ultrasound images in hepatic alveolar echinococcosis and clinical stage of the disease. Adv Med Sci 201; 64: 324-330. https://doi.org/10.1016/j.advms.2019.04.002
  14. Kratzer W, Reuter S, Hirschbuehl K, Ehrhardt AR, Mason RA, Haenle MM, Kern P, Gabelmann A. Comparison of contrast-enhanced power Doppler ultrasound (Levovist) and computed tomography in alveolar echinococcosis. Abdom Imaging 2005; 30: 286-290. https://doi.org/10.1007/s00261-004-0263-7
  15. Aoki T, Hagiwara M, Yabuki H, Ito A. Unique MRI findings for differentiation of an early stage of hepatic alveolar echinococcosis. BMJ Case Rep 2015; 2015: bcr2014208123. https://doi.org/10.1136/bcr2014-208123
  16. Graeter T, Kratzer W, Oeztuerk S, Haenle MM, Mason RA, Hillenbrand A, Kull T, Barth TF, Kern P, Gruener B. Proposal of a computed tomography classification for hepatic alveolar echinococcosis. World J Gastroenterol 201; 22: 3621-3631. https://doi.org/10.3748/wjg.v22.i13.3621
  17. Jiang C. Two cases of liver alveolar echinococcosis associated with simultaneous lung and brain metastases. Chin Med J (Engl) 2002; 115: 1898-1901.
  18. Kantarci M, Bayraktutan U, Karabulut N, Aydinli B, Ogul H, Yuce I, Calik M, Eren S, Atamanalp SS, Oto A. Alveolar echinococcosis: spectrum of findings at cross-sectional imaging. Radiographics 2012; 32: 2053-2070. https://doi.org/10.1148/rg.327125708
  19. Armoon A, Mehrian P, Soleimantabar H, Torabi S, Ghahderijani BH. Computer tomography (CT) characteristics of pulmonary cystic echinococcosis. Med Arch 2019; 73: 338-343. https://doi.org/10.5455/medarh.2019.73.338-343
  20. Belahcen M, Khattala K, Elmadi A, Bouabdellah Y. Cerebral hydatid cyst in children: report of 5 cases. Pan Afr Med J 2014; 17: 149 (in French). https://doi.org/10.11604/pamj.2014.17.149.3419
  21. Algros MP, Majo F, Bresson-Hadni S, Koch S, Godard J, Cattin F, Delbosc B, Kantelip B. Intracerebral alveolar echinococcosis. Infection 2003; 31: 63-65. https://doi.org/10.1007/s15010-002-2178-y
  22. Kvascevicius R, Lapteva O, Awar OA, Audronyte E, Neverauskiene L, Kvasceviciene E, Sokolovas V, Strupas K, Marcinkute A, Deplazes P, Mehmet Tt. Fatal liver and lung alveolar echinococcosis with newly developed neurologic symptoms due to the brain involvement. Surg J (NY) 2017; 2: e83-83e88. https://doi.org/10.1055/s-0036-1592122