Journal of the Korean Society of Radiology (대한영상의학회지)

The Korean Society of Radiology (대한영상의학회)
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The Effect of Lung Volume on the Size and Volume of Pulmonary Subsolid Nodules on CT: Intraindividual Comparison between Total Lung Capacity and Tidal Volume

전산화단층촬영에서 폐 반고형결절의 크기와 용적에 호흡이 미치는 영향: 개인 내 전폐용량과 일호흡량 간 비교

  • Hyunji Lee (Department of Radiology, Severance Hospital, Yonsei University College of Medicine) ;
  • Chansik An (Department of Radiology, National Health Insurance Service Ilsan Hospital) ;
  • Seok Jong Ryu (Department of Radiology, National Health Insurance Service Ilsan Hospital)
  • 이현지 (연세대학교 의과대학 세브란스병원 영상의학과) ;
  • 안찬식 (국민건강보험공단 일산병원 영상의학과) ;
  • 유석종 (국민건강보험공단 일산병원 영상의학과)
  • Received : 2021.08.12
  • Accepted : 2021.09.11
  • Published : 2021.11.01
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Abstract

Purpose To examine the effect of lung volume on the size and volume of pulmonary subsolid nodules (SSNs) measured on CT. Materials and Methods A total of 42 SSNs from 31 patients were included. CT examination was first performed at total lung capacity (TLC), and a section containing the nodule was additionally scanned at tidal volume (TV). The diameter and volume of each SSN, as well as the cross-sectional lung area containing the nodule, were measured. The significance of the changes in measurements between TLC and TV within the same individuals was evaluated. Results The lung area and the diameter and volume of SSNs decreased significantly at TV by 12.7 cm2, 0.5 mm, and 46.4 mm3 on average, respectively (p < 0.001), compared to those at TLC. Changes in lung area between TV and TLC were positively correlated with the change in SSN diameter (p = 0.027) and volume (p = 0.014). However, after correction (by considering the change in lung area), the changes in SSN diameter (p = 0.124) and volume (p = 0.062) were not significantly different. Conclusion SSN size and volume can be significantly affected by lung volume during CT scans of the same individuals.

목적 전산화단층촬영에서 호흡에 의한 폐 용적의 변화가 폐 반고형결절의 크기와 용적에 미치는 영향을 알아보고자 한다. 대상과 방법 총 31명의 환자에서 42개의 반고형결절이 연구에 포함되었다. 먼저 총 폐활량 상태에서 전산단층화촬영을 시행 받은 후, 결절이 포함된 부분만 일호흡용적 상태에서 추가로 촬영하였다. 각각의 반고형결절의 직경과 용적을 측정하였고, 전체 폐 용적은 결절의 중심이 있는 동측 폐의 단면적으로 추정하였다. 동일한 개인 내에서 총 폐활량과 일회 호흡량 간 측정값 변화의 유의성을 통계적으로 평가하였다. 결과 총 폐활량 상태와 비교하였을 때, 일회 호흡용적 상태에서 폐 단면적은 평균 12.7 cm2, 반고형결절의 직경 및 용적은 평균적으로 각각 0.5 mm와 46.4 mm3 감소하였다(p < 0.001). 총 폐활량 상태와 일호흡량 상태 간 폐 면적 변화는 반고형결절의 직경 변화(rho = 0.341; p = 0.027) 및 부피 변화(rho = 0.401; p = 0.014)와 유의한 양의 상관관계를 보였다. 그러나 폐 용적의 변화를 고려하여 보정한 후에는 반고형결절의 평균 직경과 부피가 총 폐활량 상태와 일호흡량 상태 간 유의한 차이가 없었다(각각 p = 0.062, p = 0.124). 결론 전산화단층촬영에서 측정한 반고형결절의 크기와 용적은 동일한 환자 내에서도 촬영 당시의 폐 용적에 유의한 영향을 받는다.

Keywords

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