Journal of the Korean Society of Radiology (대한영상의학회지)

The Korean Society of Radiology (대한영상의학회)
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CT and MRI Features of Localized Peritumoral Amyloidosis in a Patient with Head and Neck Mucosa-Associated Lymphoid Tissue Lymphoma: A Case Report

두경부 MALT 림프종 환자에서 나타난 국소적 종괴 주위 아밀로이증의 전산화단층촬영 및 자기공명영상 소견: 증례 보고

  • Han Joon Kim (Department of Radiology, Soonchunhyang University Bucheon Hospital) ;
  • Hyun Sook Hong (Department of Radiology, Soonchunhyang University Bucheon Hospital) ;
  • Ji Yoon Kim (Department of Pathology, Samkwang Medical Laboratories)
  • 김한준 (순천향대학교 부천병원 영상의학과) ;
  • 홍현숙 (순천향대학교 부천병원 영상의학과) ;
  • 김지윤 (삼광의료재단 진단본부 병리과)
  • Received : 2020.11.21
  • Accepted : 2021.01.13
  • Published : 2021.09.01
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Abstract

Amyloidosis has been reported to be associated with non-Hodgkin lymphoma. Amyloidosis and lymphoma can be related in two ways: lymphoma-associated systemic amyloidosis and peritumoral amyloidosis with lymphoma. We report a rare case of peritumoral amyloidosis in a patient with head and neck mucosa-associated lymphoid tissue lymphoma. On CT, the oropharyngeal mass showed an irregularly shaped soft-tissue density with multifocal amorphous calcifications and heterogeneous enhancement. On MRI, the mass showed heterogeneous low signal intensity on both T1- and T2-weighted images. On contrast-enhanced MR images, the mass showed good enhancement with several inner non-enhancing foci. Concurrent pathologies, such as peritumoral amyloidosis, should be considered when calcifications are noted in patients with pre-treatment lymphoma.

아밀로이드증과 비호지킨림프종과의 연관관계는 이전의 연구들에서 보고된 바 있다. 림프종과 아밀로이드증과의 연관관계는 두 개의 구분되는 범주로 나뉘는데 림프종 연관 전신성 아밀로이드증과 종괴 주위 아밀로이드증이다. 저자들은 두경부 MALT 림프종 환자에서 발생한 국소적 종괴 주위 아밀로이드증의 드문 증례를 보고하고자 한다. 전산화단층촬영에서 병변은 연조직음영을 보이는 무정형석회화를 동반한 불규칙한 모양의 종괴였으며, 조영증강 시 불균일한 조영증강을 보였다. 자기공명영상에서는 종괴가 T1 강조영상과 T2 강조영상에서 모두 불균일한 낮은 신호 강도를 보였다. 종괴는 강한 조영증강을 보였으며, 내부에는 여러 개의 조영증강되지 않는 부분들을 포함하고 있었다. 림프종 환자에서 치료 전 영상검사에서 발견된 석회화들은 종괴 주위 아밀로이드증과 같은 동반된 다른 이차성 병변을 시사하는 소견이 될 수 있을 것이다.

Keywords

Acknowledgement

This work was supported by the Soonchunhyang University Research Fund.

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