Journal of the Korean Society of Radiology (대한영상의학회지)

The Korean Society of Radiology (대한영상의학회)
권호 표지
DOI QR코드

DOI QR Code

Mammographic, Sonographic, and MRI Features of Primary Neuroendocrine Carcinoma of the Breast: A Case Report

원발성 신경내분비 유방암의 유방촬영술, 초음파, 자기공명영상 소견: 증례 보고

  • Sang Eun Park (Department of Radiology, Korea University Anam Hospital) ;
  • Kyu Ran Cho (Department of Radiology, Korea University Anam Hospital) ;
  • Sung Eun Song (Department of Radiology, Korea University Anam Hospital) ;
  • Ok Hee Woo (Department of Radiology, Korea University Guro Hospital) ;
  • Bo Kyoung Seo (Department of Radiology, Korea University Ansan Hospital) ;
  • Jeonghyun Lee (Department of Pathology, Korea University Anam Hospital)
  • 박상은 (고려대학교 안암병원 영상의학과) ;
  • 조규란 (고려대학교 안암병원 영상의학과) ;
  • 송성은 (고려대학교 안암병원 영상의학과) ;
  • 우옥희 (고려대학교 구로병원 영상의학과) ;
  • 서보경 (고려대학교 안산병원 영상의학과) ;
  • 이정현 (고려대학교 안암병원 병리과)
  • Received : 2020.05.25
  • Accepted : 2020.08.09
  • Published : 2021.05.01
Download PDF
⟨ Previous Next ⟩

Abstract

Primary neuroendocrine carcinomas of the breast are a rare, distinct category of breast carcinomas that require immunohistochemical staining for diagnosis. Currently, there is not enough evidence on the clinical pattern, prognosis, and proper management of the disease. Only few case series have described the imaging findings of neuroendocrine carcinomas of the breast. We herein present a case of a primary neuroendocrine carcinoma of the breast (small cell) presenting as a locally aggressive tumor with metastatic disease, and describe the radiologic findings.

신경내분비 유방암은 드물게 발생하며 고유한 특징을 가진 원발성 유방암의 아형으로서, 정확한 진단을 위해서는 면역조직화학염색법이 필요하다. 현재까지는 이 질환의 임상적 특징이나 예후, 올바른 치료에 대한 정확한 이해가 부족한 상태이며, 원발성 신경내분비 유방암의 영상의학적 소견은 소수의 증례에서만 보고되었다. 본 증례에서는 국소적 진행과 전이를 보인 원발성 신경내분비 유방암의 영상 소견을 보고하고자 한다.

Keywords

References

  1. Ogawa H, Nishio A, Satake H, Naganawa S, Imai T, Sawaki M, et al. Neuroendocrine tumor in the breast. Radiat Med 2008;26:28-32 
  2. Pareja F, D'Alfonso TM. Neuroendocrine neoplasms of the breast: a review focused on the updated World Health Organization (WHO) 5th edition morphologic classification. Breast J 2020;26:1160-1167 
  3. Lavigne M, Menet E, Tille JC, Lae M, Fuhrmann L, Bonneau C, et al. Comprehensive clinical and molecular analyses of neuroendocrine carcinomas of the breast. Mod Pathol 2018;31:68-82 
  4. Yoon YS, Kim SY, Lee JH, Kim SY, Han SW. Primary neuroendocrine carcinoma of the breast: radiologic and pathologic correlation. Clin Imaging 2014;38:734-738 
  5. Jeon CH, Kim SM, Jang M, Yun BL, Ahn HS, Kim SW, et al. Clinical and radiologic features of neuroendocrine breast carcinomas. J Ultrasound Med 2014;33:1511-1518 
  6. Park YM, Wu Y, Wei W, Yang WT. Primary neuroendocrine carcinoma of the breast: clinical, imaging, and histologic features. AJR Am J Roentgenol 2014;203:W221-W230 
  7. Chang ED, Kim MK, Kim JS, Whang IY. Primary neuroendocrine tumor of the breast: imaging features. Korean J Radiol 2013;14:395-399 
  8. Bergstrom C, Porembka J, Fang Y, Sarode V, Syed S. Primary neuroendocrine carcinoma of the breast. Breast J 2019;25:519-520 
  9. Wei B, Ding T, Xing Y, Wei W, Tian Z, Tang F, et al. Invasive neuroendocrine carcinoma of the breast: a distinctive subtype of aggressive mammary carcinoma. Cancer 2010;116:4463-4473 
  10. Hare F, Giri S, Patel JK, Hahn A, Martin MG. A population-based analysis of outcomes for small cell carcinoma of the breast by tumor stage and the use of radiation therapy. Springerplus 2015;4:138