DOI QR코드

DOI QR Code

Inferior Mesenteric Artery Embolization with N-Butyl Cyanoacrylate for Life-Threatening Postpartum Hemorrhage: A Report of Two Cases and Literature Review

치명적 산후출혈에서 N-Butyl Cyanoacrylate를 이용한 하장간막동맥 색전술: 두 개의 증례 보고와 문헌 고찰

  • Hae Won Yoo (Department of Radiology, Dankook University Hospital) ;
  • Min Jeong Choi (Department of Radiology, Dankook University Hospital) ;
  • Bong Man Kim (Department of Radiology, Dankook University Hospital)
  • 유해원 (단국대학교병원 영상의학과) ;
  • 최민정 (단국대학교병원 영상의학과) ;
  • 김봉만 (단국대학교병원 영상의학과)
  • Received : 2020.10.23
  • Accepted : 2020.11.22
  • Published : 2021.05.01

Abstract

The inferior mesenteric artery is a rare source of postpartum hemorrhage. We report two cases of primary postpartum hemorrhage that originated from the inferior mesenteric artery after vaginal delivery. Both patients showed signs of hypovolemic shock, and disseminated intravascular coagulation was suspected. The bleeding continued even after embolization of the uterine artery, a typical source of postpartum hemorrhage. Inferior mesenteric arteriography confirmed contrast extravasation from the superior rectal artery, and selective embolization was performed using N-butyl cyanoacrylate. This report highlights that the inferior mesenteric artery can be a source of bleeding in patients with intractable and persistent postpartum hemorrhage due to birth canal injury.

하장간막동맥은 산후출혈의 매우 드문 출혈 혈관이다. 저자들은 질분만 후 하장간막동맥에서 출혈이 있었던 일차성 산후출혈 두 개의 증례를 보고한다. 두 환자 모두 저혈량성 쇼크의 징후를 보이고 있었고, 파종성혈관내응고가 의심되는 상태였다. 산후출혈의 흔한 출혈 혈관인 자궁동맥을 색전한 후에도 출혈은 지속되었다. 하장간막동맥 혈관조영술에서 상직장동맥으로부터 조영제의 혈관외누출이 확인되어 N-butyl cyanoacrylate를 이용한 선택적 색전술을 시행하였다. 이 증례를 통해 산도 손상에 의한 산후출혈이 조절되지 않고 지속될 때 하장간막동맥이 출혈 동맥일 수 있다는 점을 강조하고자 한다.

Keywords

References

  1. Chen C, Chu HH, Shin JH, Li HL, Ko HK, Kim JW, et al. Inferior mesenteric artery embolization for persistent postpartum hemorrhage after sufficient bilateral iliac arteries embolization: safety and efficacy in eight patients. Br J Radiol 2019;92:20180896
  2. Koganemaru M, Nonoshita M, Iwamoto R, Kuhara A, Nabeta M, Kusumoto M, et al. Endovascular management of intractable postpartum hemorrhage caused by vaginal laceration. Cardiovasc Intervent Radiol 2016;39:1159-1164 https://doi.org/10.1007/s00270-016-1309-2
  3. Cheng HH, Tsang LL, Hsu TY, Kung CT, Ou CY, Chang CD, et al. Transcatheter arterial embolization as firstline rescue in intractable primary postpartum hemorrhage: assessment, outcome, and subsequent fertility. J Formos Med Assoc 2017;116:380-387 https://doi.org/10.1016/j.jfma.2016.06.011
  4. Kwon Y, So YH, Kim BJ, Kim SM, Choi YH, Moon MH. Uterine artery embolization in patients with postpartum hemorrhage: clinical efficacy and safety of treatment with N-butyl-2-cyanoacrylate. J Korean Soc Radiol 2019;80:88-97 https://doi.org/10.3348/jksr.2019.80.1.88
  5. Kim MD. Uterine artery embolization. In The Society of Interventional Radiology, ed. Interventional radiology. 2nd ed. Seoul: Ilchokak 2014:414-430
  6. Lee SM, Shin JH, Shim JJ, Yoon KW, Cho YJ, Kim JW, et al. Postpartum haemorrhage due to genital tract injury after vaginal delivery: safety and efficacy of transcatheter arterial embolisation. Eur Radiol 2018;28:4800-4809 https://doi.org/10.1007/s00330-018-5490-3
  7. Kim CH, Lee SJ, Jeon GS, Kang SH, Kim HC. Embolization of inferior mesenteric artery for intractable intrapelvic and vaginal bleeding after hysterectomy. J Minim Invasive Gynecol 2016;23:1191-1194 https://doi.org/10.1016/j.jmig.2016.07.013
  8. Susan S. Gray's anatomy: the anatomical basis of clinical practice. 40th ed. London: Elsevier/Churchill Livingstone 2008:1154, 1281, 1289-1290
  9. Goto Y, Kanno Y, Hayashi M, Mitsuzuka K, Sekiguchi T, Suzuki T, et al. Retained products of conception fed by the inferior mesenteric artery: a case report. Tokai J Exp Clin Med 2020;45:131-135
  10. Yonemitsu T, Kawai N, Sato M, Tanihata H, Takasaka I, Nakai M, et al. Evaluation of transcatheter arterial embolization with gelatin sponge particles, microcoils, and n-butyl cyanoacrylate for acute arterial bleeding in a coagulopathic condition. J Vasc Interv Radiol 2009;20:1176-1187  https://doi.org/10.1016/j.jvir.2009.06.005