Journal of the Korean Society of Radiology (대한영상의학회지)

The Korean Society of Radiology (대한영상의학회)
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Bilateral Breast Cancer in a Patient with Neurofibromatosis Type 1: A Case Report

제1형 신경섬유종증 환자에서 발생한 양측성 유방암: 증례 보고

  • Sang Hwa Woo (Department of Radiology, Inje University Haeundae Paik Hospital) ;
  • Hyun Kyung Jung (Department of Radiology, Inje University Haeundae Paik Hospital) ;
  • Woogyeong Kim (Department of Pathology, Inje University Haeundae Paik Hospital)
  • 우상화 (인제대학교 의과대학 해운대백병원 영상의학과) ;
  • 정현경 (인제대학교 의과대학 해운대백병원 영상의학과) ;
  • 김우경 (인제대학교 의과대학 해운대백병원 병리과)
  • Received : 2020.05.06
  • Accepted : 2020.06.20
  • Published : 2021.03.01
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Abstract

Neurofibromatosis type 1 (NF1) is a rare neuroectodermal disease that is associated with an increased risk of malignancy. Here, we report a rare case of bilateral breast cancer in a 49-year-old woman with NF1 that presented as a microlobulated oval hypoechoic mass and a complex cystic solid mass on sonography. She underwent bilateral mastectomy. The masses were diagnosed as invasive ductal carcinoma, ductal carcinoma in situ, and a malignant peripheral nerve sheath tumor. We describe the imaging findings, including ultrasonography, CT, and 18F-fluorodeoxyglucose PET.

제1형 신경섬유종증은 상염색제 우성으로 유전되는 신경외배영성 질환으로 다양한 악성 종양이 발생할 수 있다. 하지만 유방암이 발생한 보고는 드물다. 이에 저자들은 제1형 신경섬유종증 환자에서 발생한 양측성 유방암 증례를 영상 소견과 함께 보고하고자 한다.

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References

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