DOI QR코드

DOI QR Code

이하선에 발생한 아구양 외투세포 림프종 1예

A Case of Blastoid Mantle Cell Lymphoma Occurring in the Parotid Gland

  • 백문승 (중앙보훈병원 이비인후과) ;
  • 문성규 (중앙보훈병원 이비인후과) ;
  • 이미지 (중앙보훈병원 병리과) ;
  • 김승우 (중앙보훈병원 이비인후과)
  • Beag, Moon Seung (Department of Otorhinolaryngology-Head and Neck Surgery Veterans Health Service Medical Center) ;
  • Moon, Seong Kyu (Department of Otorhinolaryngology-Head and Neck Surgery Veterans Health Service Medical Center) ;
  • Lee, Mi Ji (Department of Pathology Veterans Health Service Medical Center) ;
  • Kim, Seung Woo (Department of Otorhinolaryngology-Head and Neck Surgery Veterans Health Service Medical Center)
  • 투고 : 2020.08.30
  • 심사 : 2020.11.25
  • 발행 : 2021.05.31

초록

Mantle cell lymphoma (MCL) is a rare subtype of B-cell neoplasm and it accounts for about 3~6% of all non-Hodgkin's lymphomas. It occurs mainly in middle-aged or elderly man, involving the extra-nodal sites such as gastrointestinal tract, bone marrow and Waldeyer's ring. The incidence of the MCL in salivary gland is about 3%. The blastoid MCL is a rare variant and it has a very aggressive clinical course. It is extremely rare to be arising from the parotid gland. To our knowledge, similar case has not been reported in domestic literature, one case has been described in English literature. We experienced a rare and unique disease entity and report it with brief literature review.

키워드

참고문헌

  1. Abukhiran I, Jasser J, Hoffman HT, Syrbu S. Mantle Cell Lymphoma Involving Major and Minor Salivary Glands With Parotid Sparing. JAMA Otolaryngology-Head & Neck Surgery. 2020;146:309-311. https://doi.org/10.1001/jamaoto.2019.4116
  2. Ambinder AJ, Shenoy PJ, Nastoupil LJ, Flowers CR. Using primary site as a predictor of survival in mantle cell lymphoma. Cancer. 2013;119:1570-1577. https://doi.org/10.1002/cncr.27898
  3. Dreyling M, Klapper W, Rule S. Blastoid and pleomorphic mantle cell lymphoma: still a diagnostic and therapeutic challenge! Blood. 2018;132:2722-2729. https://doi.org/10.1182/blood-2017-08-737502
  4. Bonilla-Abadia F, Perez MA, Munoz-Buitron E, Rosales JD, Canas CA, Tobon GJ. Fatal Blastoid Variant Mantle Cell Lymphoma in a Patient with Sjogren's Syndrome. Case reports in rheumatology. 2013;2013:831708. https://doi.org/10.1155/2013/831708
  5. Chung WY, Lee HS, Seo JH, Yang W-I, Park CS. Parotid Mass as First Presentation of Malignant Lymphoma. Korean J Head Neck Oncol. 2001;17:26-31.
  6. Shum JW, Emmerling M, Lubek JE, Ord RA. Parotid lymphoma: a review of clinical presentation and management. Oral surgery, oral medicine, oral pathology and oral radiology. 2014; 118:e1-e5. https://doi.org/10.1016/j.oooo.2013.10.013
  7. Yaprak N, Temel IC, Derin AT, Guney K. Diagnosis and treatment of malignant lymphomas of parotid gland. Kulak Burun Bogaz Ihtis Derg. 2015;25:346-349. https://doi.org/10.5606/kbbihtisas.2015.98254
  8. Kwak SG, Kim CD, Kim YJ, Kim SW. A Case of Mantle Cell Lymphoma Involving the Parotid Gland and Upper Neck. Korean J Head Neck Oncol. 2015;31:43-46.
  9. Pott C, Schrader C, Bruggemann M, Ritgen M, Harder L, Raff T, et al. Blastoid variant of mantle cell lymphoma: late progression from classical mantle cell lymphoma and quantitation of minimal residual disease. European journal of haematology. 2005;74: 353-358. https://doi.org/10.1111/j.1600-0609.2005.00409.x
  10. Bernard M, Gressin R, Lefrere F, Drenou B, Branger B, Caulet-Maugendre S, et al. Blastic variant of mantle cell lymphoma: a rare but highly aggressive subtype. Leukemia. 2001;15: 1785-1791. https://doi.org/10.1038/sj.leu.2402272
  11. Pilavaki M, Athanasiadou A, Iordanidis F, Karakozoglou T, Palladas P. Magnetic resonance imaging with pathological correlation in a case of mantle cell lymphoma of the parotid gland: a case report. Journal of medical case reports. 2010;4:1-5. https://doi.org/10.1186/1752-1947-4-1
  12. Demharter J, Muller P, Wagner T, Schlimok G, Haude K, Bohndorf K. Percutaneous core-needle biopsy of enlarged lymph nodes in the diagnosis and subclassification of malignant lymphomas. European radiology. 2001;11:276-283. https://doi.org/10.1007/s003300000540
  13. Eryilmaz A, Basal Y, Gunel C, Doger FK, Kadikoylu G. Mantle cell lymphoma revealed with superficial parotidectomy. ENTcase. 2016;2:21-27.
  14. Mansoor A, Akbari M, Auer I, Lai R. Cyclin D1 and t (11; 14)-positive B-cell neoplasms resembling marginal zone B-cell lymphoma: a morphological variant of mantle cell lymphoma. Human pathology. 2007;38:797-802. https://doi.org/10.1016/j.humpath.2006.10.017