Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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A Case of Mucinous Cystadenocarcinoma in Labial Mucosa of Upper Lip

상순 구순점막에 발생한 점액낭선암종 1예

  • Um, Jung Hwan (Department of Plastic and Reconstructive Surgery, Konkuk university Chungju Hospital, Konkuk University School of Medicine) ;
  • Jo, Dong In (Department of Plastic and Reconstructive Surgery, Konkuk university Chungju Hospital, Konkuk University School of Medicine) ;
  • Kim, Soon Heum (Department of Plastic and Reconstructive Surgery, Konkuk university Chungju Hospital, Konkuk University School of Medicine)
  • 엄정환 (건국대학교 의과대학 성형외과학교실) ;
  • 조동인 (건국대학교 의과대학 성형외과학교실) ;
  • 김순흠 (건국대학교 의과대학 성형외과학교실)
  • Received : 2020.12.03
  • Accepted : 2021.03.23
  • Published : 2021.05.31
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Abstract

Mucinous cystadenocarcinoma (MCA) is a malignant tumor that mainly occurs in the breast or ovary, but MCA is internationally rarely reported in head and neck region. Especially MCA in minor salivary gland of oral cavity is even more rare. It is characterized by cystic spaces lining of epithelial cells containing intracytoplasmic mucin. We report a case of MCA in the labial mucosa of upper lip considered to develop from minor salivary gland with a review of literatures.

Keywords

Acknowledgement

This study was approved by the Institutional Review Board (IRB) of our medical institution (IRB No. KUCH 2020-11-033). This study conforms to the Declaration of Helsinki ethical principles for medical research.

References

  1. Aydin E, Turkoglu S, Ozen O, Akkuzu B. Mucinous cystadenocarcinoma of a minor salivary gland in the upper lip: case report. Auris Nasus Larynx. 2005;32:301-304. https://doi.org/10.1016/j.anl.2005.03.018
  2. de Araujo VC, de Sousa SO, Lopes EA, de Araujo NS, Sesso A. Mucus-producing adenopapillary carcinoma of minor salivary gland origin with signet ring cells and intracytoplasmic lumina. A light and electron microscopic study. Arch Otorhinolaryngol. 1988;245:145-150. https://doi.org/10.1007/BF00464016
  3. Schneller J, Solomon M, Webber CA, Nasim M. Mucinous cystadenocarcinoma of the parotid gland: report of a case with fine needle aspiration findings and histologic correlation. Acta Cytol. 2001;45:605-609. https://doi.org/10.1159/000327872
  4. Honma N, Sakamoto G, Ikenaga M, Kuroiwa K, Younes M, Takubo K. Mucinous cystadenocarcinoma of the breast: a case report and review of the literature. Arch Pathol Lab Med. 2003;127: 1031-1033. https://doi.org/10.5858/2003-127-1031-MCOTBA
  5. Kardos TB, Ferguson JW, McMillan MD. Mucus-producing adenopapillary carcinoma of the oral cavity. Int J Oral Maxillofac Surg. 1992;21:160-162. https://doi.org/10.1016/S0901-5027(05)80785-4
  6. Foss RD, Ellis GL, Auclair PL. Salivary gland cystadenocarcinomas. A clinicopathologic study of 57 cases. Am J Surg Pathol. 1996; 20:1440-1447. https://doi.org/10.1097/00000478-199612000-00002
  7. Koenig C, Tavassoli FA. Mucinous cystadenocarcinoma of the breast. Am J Surg Pathol. 1998;22:698-703. https://doi.org/10.1097/00000478-199806000-00006
  8. Blanck C, Eneroth CM, Jakobsson PA. Mucus-producing adenopapillary (non-epidermoid) carcinoma of the parotid gland. Cancer. 1971;28:676-685. https://doi.org/10.1002/1097-0142(197109)28:3<676::AID-CNCR2820280324>3.0.CO;2-A
  9. Kennedy RA. WHO is in and WHO is out of the mouth, salivary glands, and jaws sections of the 4th edition of the WHO classification of head and neck tumours. Br J Oral Maxillofac Surg. 2018;56:90-95. https://doi.org/10.1016/j.bjoms.2017.12.009
  10. Zhang C, Chen C, Wang J. Submandibular gland cystadenocarcinoma with mucinous adenocarcinoma-like areas: a case report. Diagn Pathol. 2014;9:87. https://doi.org/10.1186/1746-1596-9-87
  11. Mano T, Uchida K, Okafuji M, Horinaga D, Nagatsuka H, Ueyama Y. A case of mucinous adenocarcinoma of the palate. Japanese Journal of Oral & Maxillofacial Surgery. 2006;52: 507-510. https://doi.org/10.5794/jjoms.52.507
  12. Swanson GM, Burns PB. Cancers of the salivary gland: workplace risks among women and men. Ann Epidemiol. 1997;7:369-374. https://doi.org/10.1016/S1047-2797(97)00041-0
  13. Kruse AL, Gratz KW, Obwegeser JA, Lubbers HT. Malignant minor salivary gland tumors: a retrospective study of 27 cases. Oral Maxillofac Surg. 2010;14:203-209. https://doi.org/10.1007/s10006-010-0217-x
  14. Kang JY, Choi IJ, Lee BC. A Case Report of Mucinous Adenocarcinoma of the Oral Tongue. Korean J Head Neck Oncol. 2018;34:35-38. https://doi.org/10.21593/kjhno/2018.34.2.35