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Evaluating the Effects of Dose Rate on Dynamic Intensity-Modulated Radiation Therapy Quality Assurance

  • Kim, Kwon Hee (Department of Biomedical Engineering and Biomedicine & Health Science, College of Medicine, The Catholic University of Korea) ;
  • Back, Tae Seong (Department of Radiation Oncology, National Health Insurance Service, Ilsan Hospital) ;
  • Chung, Eun Ji (Department of Radiation Oncology, National Health Insurance Service, Ilsan Hospital) ;
  • Suh, Tae Suk (Department of Biomedical Engineering and Biomedicine & Health Science, College of Medicine, The Catholic University of Korea) ;
  • Sung, Wonmo (Department of Biomedical Engineering and Biomedicine & Health Science, College of Medicine, The Catholic University of Korea)
  • 투고 : 2021.09.15
  • 심사 : 2021.11.24
  • 발행 : 2021.12.31

초록

Purpose: To investigate the effects of dose rate on intensity-modulated radiation therapy (IMRT) quality assurance (QA). Methods: We performed gamma tests using portal dose image prediction and log files of a multileaf collimator. Thirty treatment plans were randomly selected for the IMRT QA plan, and three verification plans for each treatment plan were generated with different dose rates (200, 400, and 600 monitor units [MU]/min). These verification plans were delivered to an electronic portal imager attached to a Varian medical linear accelerator, which recorded and compared with the planned dose. Root-mean-square (RMS) error values of the log files were also compared. Results: With an increase in dose rate, the 2%/2-mm gamma passing rate decreased from 90.9% to 85.5%, indicating that a higher dose rate was associated with lower radiation delivery accuracy. Accordingly, the average RMS error value increased from 0.0170 to 0.0381 cm as dose rate increased. In contrast, the radiation delivery time reduced from 3.83 to 1.49 minutes as the dose rate increased from 200 to 600 MU/min. Conclusions: Our results indicated that radiation delivery accuracy was lower at higher dose rates; however, the accuracy was still clinically acceptable at dose rates of up to 600 MU/min.

키워드

과제정보

This work was supported by grants from the National Research Foundation of Korea (NRF, No. 2021R1C1C1005930 and No. 2018R1A2B2005343) funded by the Korea government (MSIT).

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