DOI QR코드

DOI QR Code

Clinical Features and Outcomes of Superficial Keratectomy and Conjunctival Advancement Hood Flap in Three Dogs with Different Extents of Corneal Edema

  • Kim, Youngsam (Dana Animal Hospital Eye Center) ;
  • Nam, Sunhwa (Dana Animal Hospital Eye Center) ;
  • Kang, Seonmi (Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University)
  • Received : 2020.10.31
  • Accepted : 2021.04.05
  • Published : 2021.04.30

Abstract

Three dogs with different extents of corneal edema were presented to the Dana Animal Hospital Eye Center. The dogs (3 eyes) were diagnosed with corneal endothelial degeneration with clinical signs of corneal edema, conjunctival hyperemia, and mild blepharospasm through a full ophthalmic examination. For the treatment of corneal edema, superficial keratectomy using a crescent microsurgical knife was performed, and a conjunctival advancement hood flap was applied to the stromal defects. In two cases where corneal edema and opacity were observed only in a part of the cornea, corneal edema was reduced and did not progress to other parts of the cornea and corneal transparency and vision were also well-maintained during the follow-up on days 349 and 231 after the surgery. In a case where the whole cornea was edematous and cloudy, corneal edema and opacity had not clearly improved at the last follow-up on day 275 after the surgery. In conclusion, SKCAHF relieved corneal edema and improved vision, and the prognosis tended to be better when there was less corneal edema caused by CED.

Keywords

References

  1. Adamis AP, Filatov V, Tripathi BJ, Tripathi RC. Fuchs' endothelial dystrophy of the cornea. Surv Ophthalmol 1993; 38: 149-168. https://doi.org/10.1016/0039-6257(93)90099-S
  2. Armour MD, Askew TE, Eghrari AO. Endothelial keratoplasty for corneal endothelial dystrophy in a dog. Vet Ophthalmol 2019; 4: 545-551. https://doi.org/10.1111/vop.12670
  3. Bayley KD, Read RA, Gates MC. Superficial keratectomy as a treatment for non-healing corneal ulceration associated with primary corneal endothelial degeneration. Vet Ophthalmol 2019; 4: 485-492. https://doi.org/10.1111/vop.12617
  4. Brooks DE, Samuelson DA, Smith PJ. Corneal endothelial cell degeneration in a German shepherd dog. J Small Anim Pract 1990; 31: 32-35.
  5. Gelatt KN, Brooks DE. Surgery of the cornea and sclera. In: Veterinary ophthalmic surgery, 1st ed. Maryland Height: Elsevier Saunders. 2011: 191-236.
  6. Gilger BC, Ollivier FJ, Bentley E. Diseases and surgery of the canine corneal and sclera. In: Veterinary ophthalmology, 4th ed. Ames: Blackwell Publishing. 2007: 690-752.
  7. Gwin RM, Lerner I, Warren JK, Gum G. Decrease in canine corneal endothelial cell density and increase in corneal thickness as functions of age. Invest Ophthalmol Vis Sci 1982; 22: 267-271.
  8. Horikawa T, Thomasy SM, Stanley AA, Calderon AS, Li J, Linton LL, Murphy CJ. Superficial keratectomy and conjunctival advancement hood flap (SKCAHF) for the management of bullous keratopathy: validation in dogs with spontaneous disease. Corena 2016; 10: 1295-1304.
  9. Kafarnik C, Fritsche J, Reese S. In vivo confocal microscopy in the normal corneas of cats, dogs and birds. Vet Ophthalmol 2007;10: 222-230. https://doi.org/10.1111/j.1463-5224.2007.00543.x
  10. Knezovic I, Dekaris I, Gabric N, Cerovski J, Barisic A, Bosnar D, Rastegorac P, Parac A. Therapeutic efficacy of 5% NaCl hypertonic solution in patients with bullous keratopathy. Coll Antropol 2006; 30: 405-408.
  11. Maggs DJ. Diseases of the cornea and sclera. In: Slatter's Fundamentals of Veterinary Ophthalmology, 6th ed. Saint Louis: Elsevier. 2018: 213-253.
  12. Michau TM, Gilger BC, Maggio F, Davidson MG. Use thermokeratoplasty for treatment of ulcerative keratitis and bullous keratopathy secondary to corneal endothelial disease in dogs: 13 cases (1994-2001). J Am Vet Med Assoc 2003; 5: 607-612.
  13. Moore PA. Cornea and sclera. In: Ophthalmic disease in veterinary medicine, 2nd ed. Boca Raton: CRC press. 2019: 315-410.
  14. Ohguro N, Matsuda M, Kinoshita S. The effects of denatured sodium hyaluronate on the corneal endothelium in cats. Am J Ophthalmol 1991; 112: 424-430. https://doi.org/10.1016/s0002-9394(14)76252-x
  15. Pot SA, Gallhofer NS, Walser-Reinhardt L, Hafezi F, Spiess BM. Treatment of bullous keratopathy with corneal collagen cross-linking in two dogs. Vet Ophthalmol 2015; 18: 168-173. https://doi.org/10.1111/vop.12137
  16. Sanchez RF. The cornea. In: BSAVA manual of canine and feline ophthalmology. 3rd ed. Gloucester: BSAVA. 2014: 200-231.