References
- Joo JS, Park KC, Song JY, Kim DH, Lee KJ, Kwon YC, et al. 2010. A thin-layer liquid culture technique for the growth of Helicobacter pylori. Helicobacter 15: 295-302. https://doi.org/10.1111/j.1523-5378.2010.00767.x
- Blaser MJ, Atherton JC. 2004. Helicobacter pylori persistence: biology and disease. J. Clin. Investig. 113: 321-333. https://doi.org/10.1172/JCI20925
- Sterbenc A, Jarc E, Poljak M, Homan M. 2019. Helicobacter pylori virulence genes. World J. Gastroenterol. 25: 4870-4884. https://doi.org/10.3748/wjg.v25.i33.4870
- Matsuo Y, Kido Y, Yamaoka Y. 2017. Helicobacter pylori outer membrane protein-related pathogenesis. Toxins (Basel) 9: 101. https://doi.org/10.3390/toxins9030101
- Yamaoka Y, Graham DY. 2014. Helicobacter pylori virulence and cancer pathogenesis. Future Oncol. 10: 1487-1500. https://doi.org/10.2217/fon.14.29
- Yamaoka Y. 2010. Mechanisms of disease: Helicobacter pylori virulence factors. Nat. Rev. Gastroenterol. Hepatol. 7: 629-641. https://doi.org/10.1038/nrgastro.2010.154
- Malaty HM. 2007. Epidemiology of Helicobacter pylori infection. Best Pract. Res. Clin. Gastroenterol. 21: 205-214. https://doi.org/10.1016/j.bpg.2006.10.005
- Youn HS, Baik SC, Cho YK, Woo HO, Ahn YO, Kim K, et al. 1998. Comparison of Helicobacter pylori infection between Fukuoka, Japan and Chinju, Korea. Helicobacter 3: 9-14. https://doi.org/10.1046/j.1523-5378.1998.08011.x
- Shin A, Kim J, Park S. 2011. Gastric cancer epidemiology in Korea. J. Gastric Cancer 11: 135-140. https://doi.org/10.5230/jgc.2011.11.3.135
- Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. 2010. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int. J. Cancer 127: 2893-2917. https://doi.org/10.1002/ijc.25516
- Fock KM, Ang TL. 2010. Epidemiology of Helicobacter pylori infection and gastric cancer in Asia. J. Gastroenterol. Hepatol. 25: 479-486. https://doi.org/10.1111/j.1440-1746.2009.06188.x
- Alm RA. 1999. Analysis of the genetic diversity of Helicobacter pylori: the tale of two genomes. J. Mol. Med. 77: 834-846. https://doi.org/10.1007/s001099900067
- Shiota S, Suzuki R, Yamaoka Y. 2013. The significance of virulence factors in Helicobacter pylori. J. Dig. Dis. 14: 341-349. https://doi.org/10.1111/1751-2980.12054
- Ando T, Wassenaar TM, Peek RM, Aras RA, Tschumi AI, van Doorn LJ, et al. 2002. A Helicobacter pylori restriction endonuclease-replacing gene, hrgA, is associated with gastric cancer in Asian strains. Cancer Res. 62: 2385-2389.
- Choe YH, Kim PS, Lee DH, Kim HK, Kim YS, Shin YW, et al. 2002. Diverse vacA allelic types of Helicobacter pylori in Korea and clinical correlation. Yonsei Med. J. 43: 351-356. https://doi.org/10.3349/ymj.2002.43.3.351
- Yamaoka Y, Kodama T, Gutierrez O, Kim JG, Kashima K, Graham DY. 1999. Relationship between Helicobacter pylori iceA, cagA, and vacA status and clinical outcome: studies in four different countries. J. Clin. Microbiol. 37: 2274-2279. https://doi.org/10.1128/JCM.37.7.2274-2279.1999
- Kao CY, Sheu BS, Wu JJ. 2016. Helicobacter pylori infection: An overview of bacterial virulence factors and pathogenesis. Biomed. J. 39: 14-23. https://doi.org/10.1016/j.bj.2015.06.002
- McClain MS, Beckett AC, Cover TL. 2017. Helicobacter pylori vacuolating toxin and gastric cancer. Toxins (Basel) 9: 316. https://doi.org/10.3390/toxins9100316
- Kalali B, Mejias Luque R, Javaheri A, Gerhard M. 2014. H. pylori virulence factors: influence on immune system and pathology. Mediators Inflamm. 2014: ID 426309.
- Rhee KH. 1990. Prevalence of Helicobacter pylori infection in Korea. J. Korean Soc. Microbiol. 25: 475-490.
- Ko JS, Kim KM, Oh YL, Seo JK. 2008. cagA, vacA, and iceA genotypes of Helicobacter pylori in Korean children. Pediatr. Int. 50: 628-631. https://doi.org/10.1111/j.1442-200X.2008.02641.x
- Lu H, Hsu PI, Graham DY, Yamaoka Y. 2005. Duodenal ulcer promoting gene of Helicobacter pylori. Gastroenterology 128: 833-848. https://doi.org/10.1053/j.gastro.2005.01.009
- Kim N, Park RY, Cho SI, Lim SH, Lee KH, Lee W, et al. 2008. Helicobacter pylori infection and development of gastric cancer in Korea: long-term follow-up. J. Clin. Gastroenterol. 42: 448-454. https://doi.org/10.1097/MCG.0b013e318046eac3
- Senkovich OA, Yin J, Ekshyyan V, Conant C, Traylor J, Adegboyega P, et al. 2011. Helicobacter pylori AlpA and AlpB bind host laminin and influence gastric inflammation in gerbils. Infect. Immun. 79: 3106-3116. https://doi.org/10.1128/IAI.01275-10
- De Jonge R, Durrani Z, Rijpkema SG, Kuipers EJ, van Vliet AH, Kusters JG. 2004. Role of the Helicobacter pylori outer-membrane proteins AlpA and AlpB in colonization of the guinea pig stomach. J. Med. Microbiol. 53: 375-379. https://doi.org/10.1099/jmm.0.45551-0
- Gerhard M, Lehn N, Neumayer N, Boren T, Rad R, Schepp W, et al. 1999. Clinical relevance of the Helicobacter pylori gene for bloodgroup antigen-binding adhesin. Proc. Natl. Acad. Sci. USA 96: 12778-12783. https://doi.org/10.1073/pnas.96.22.12778
- Zambon C, Navaglia F, Basso D, Rugge M, Plebani M. 2003. Helicobacter pylori babA2, cagA, and s1 vacA genes work synergistically in causing intestinal metaplasia. J. Clin. Pathol. 56: 287-291. https://doi.org/10.1136/jcp.56.4.287
- Fujimoto S, Ojo OO, Arnqvist A, Wu JY, Odenbreit S, Haas R, et al. 2007. Helicobacter pylori BabA expression, gastric mucosal injury, and clinical outcome. Clin. Gastroenterol. Hepatol. 5: 49-58. https://doi.org/10.1016/j.cgh.2006.09.015
- Kennemann L, Brenneke B, Andres S, Engstrand L, Meyer TF, Aebischer T, et al. 2012. In vivo sequence variation in HopZ, a phase-variable outer membrane protein of Helicobacter pylori. Infect. Immun. 80: 4364-4373. https://doi.org/10.1128/IAI.00977-12
- Dossumbekova A, Prinz C, Mages J, Lang R, Kusters JG, Van Vliet AH, et al. 2006. Helicobacter pylori HopH (OipA) and bacterial pathogenicity: genetic and functional genomic analysis of hopH gene polymorphisms. J. Infect. Dis. 194: 1346-1355. https://doi.org/10.1086/508426
- Horridge DN, Begley AA, Kim J, Aravindan N, Fan K, Forsyth MH. 2017. Outer inflammatory protein a (OipA) of Helicobacter pylori is regulated by host cell contact and mediates CagA translocation and interleukin-8 response only in the presence of a functional cag pathogenicity island type IV secretion system. Pathog. Dis. 75: ftx113.
- Odenbreit S. 2005. Adherence properties of Helicobacter pylori: impact on pathogenesis and adaptation to the host. Int. J. Med. Microbiol. 295: 317-324. https://doi.org/10.1016/j.ijmm.2005.06.003
- Peek Jr RM, Thompson SA, Donahue JP, Tham KT, Atherton JC, Blaser MJ, et al. 1998. Adherence to gastric epithelial cells induces expression of a Helicobacter pylori gene, iceA, that is associated with clinical outcome. Proc. Assoc. Am. Physicians 110: 531-544.
- Kim SY, Woo CW, Lee YM, Son BR, Kim JW, Chae HB, et al. 2001. Genotyping CagA, VacA subtype, IceA1, and BabA of Helicobacter pylori isolates from Korean patients, and their association with gastroduodenal diseases. J. Korean Med. Sci. 16: 579-584. https://doi.org/10.3346/jkms.2001.16.5.579
- Baik SC, Kim JB, Cho MJ, Kim YC, Park CK, Ryou HH, et al. 1990. Prevalence of Helicobacter pylori infection among normal Korean adults. J. Korean Soc. Microbiol. 25: 455-462.
- Baik SC, Youn HS, Chung MH, Lee WK, Cho MJ, Ko GH, et al. 1996. Increased oxidative DNA damage in Helicobacter pylori-infected human gastric mucosa. Cancer Res. 56: 1279-1282.
- Song GY, Chang MW. 1999. Antibiotic susceptibility of Helicobacter pylori and the combination effect of antibiotics on the antibiotic-resistant H. pylori strains. J. Korean Soc. Microbiol. 34: 543-554.
- Monstein HJ, Nikpour Badr S, Jonasson J. 2001. Rapid molecular identification and subtyping of Helicobacter pylori by pyrosequencing of the 16S rDNA variable V1 and V3 regions. FEMS Microbiol. Lett. 199: 103-107. https://doi.org/10.1016/S0378-1097(01)00171-9
- Taylor NS, Fox JG, Akopyants NS, Berg DE, Thompson N, Shames B, et al. 1995. Long-term colonization with single and multiple strains of Helicobacter pylori assessed by DNA fingerprinting. J. Clin. Microbiol. 33: 918-923. https://doi.org/10.1128/jcm.33.4.918-923.1995
- Ohta-Tada U, Takagi A, Koga Y, Kamiya S, Miwa T. 1997. Flagellin gene diversity among Helicobacter pylori strains and IL-8 secretion from gastric epithelial cells. Scand. J. Gastroenterol. 32: 455-459. https://doi.org/10.3109/00365529709025080
- Park JY, Forman D, Waskito LA, Yamaoka Y, Crabtree JE. 2018. Epidemiology of Helicobacter pylori and CagA-positive infections and global variations in gastric cancer. Toxins (Basel) 10: 163. https://doi.org/10.3390/toxins10040163
- Berthenet E, Yahara K, Thorell K, Pascoe B, Meric G, Mikhail JM, et al. 2018. A GWAS on Helicobacter pylori strains points to genetic variants associated with gastric cancer risk. BMC Biol. 16: 84. https://doi.org/10.1186/s12915-018-0550-3
- Soyfoo DM, Doomah YH, Xu D, Zhang C, Sang HM, Liu YY, et al. 2021. New genotypes of Helicobacter pylori VacA d-region identified from global strains. BMC Mol. Cell. Biol. 22: 4. https://doi.org/10.1186/s12860-020-00338-2
- Aydin F, Kaklikkaya N, Ozgur O, Cubukcu K, Kilic A, Tosun I, et al. 2004. Distribution of vacA alleles and cagA status of Helicobacter pylori in peptic ulcer disease and non-ulcer dyspepsia. Clin. Microbiol. Infect. 10: 1102-1104. https://doi.org/10.1111/j.1469-0691.2004.00989.x
- Hocker M, Hohenberger P. 2003. Helicobacter pylori virulence factors-one part of a big picture. Lancet 362: 1231-1233. https://doi.org/10.1016/S0140-6736(03)14547-3
- Homan M, Luzar B, Kocjan BJ, Mocilnik T, Shrestha M, Kveder M, et al. 2009. Prevalence and clinical relevance of cagA, vacA, and iceA genotypes of Helicobacter pylori isolated from Slovenian children. J. Pediatr. Gastroenterol. Nutr. 49: 289-296. https://doi.org/10.1097/MPG.0b013e31818f09f2
- Posselt G, Backert S, Wessler S. 2013. The functional interplay of Helicobacter pylori factors with gastric epithelial cells induces a multi-step process in pathogenesis. Cell Commun. Signal. 11: 77. https://doi.org/10.1186/1478-811X-11-77
- Lu H, Wu JY, Beswick EJ, Ohno T, Odenbreit S, Haas R, et al. 2007. Functional and intracellular signaling differences associated with the Helicobacter pylori AlpAB adhesin from Western and East Asian strains. J. Biol. Chem. 282: 6242-6254. https://doi.org/10.1074/jbc.M611178200
- Chen MY, He CY, Meng X, Yuan Y. 2013. Association of Helicobacter pylori babA2 with peptic ulcer disease and gastric cancer. World J. Gastroenterol. 19: 4242-4251. https://doi.org/10.3748/wjg.v19.i26.4242
- Homan M, Sterbenc A, Kocjan BJ, Luzar B, Zidar N, Poljak M. 2014. Prevalence of the Helicobacter pylori babA2 gene and correlation with the degree of gastritis in infected Slovenian children. Antonie Van Leeuwenhoek. 106: 637-645. https://doi.org/10.1007/s10482-014-0234-0
- Merrell DS, Goodrich ML, Otto G, Tompkins LS, Falkow S. 2003. pH-regulated gene expression of the gastric pathogen Helicobacter pylori. Infect. Immun. 71: 3529-3539. https://doi.org/10.1128/IAI.71.6.3529-3539.2003
- Xu C, Soyfoo DM, Wu Y, Xu S. 2020. Virulence of Helicobacter pylori outer membrane proteins: An updated review. Eur. J. Clin. Microbiol. Infect. Dis. 39: 1821-1830. https://doi.org/10.1007/s10096-020-03948-y
- Servetas SL, Kim A, Su H, Cha JH, Merrell DS. 2018. Comparative analysis of the Hom family of outer membrane proteins in isolates from two geographically distinct regions: the United States and South Korea. Helicobacter 23: e12461. https://doi.org/10.1111/hel.12461
- Farzi N, Yadegar A, Aghdaei HA, Yamaoka Y, Zali MR. 2018. Genetic diversity and functional analysis of oipA gene in association with other virulence factors among Helicobacter pylori isolates from Iranian patients with different gastric diseases. Infect. Genet. Evol. 60: 26-34. https://doi.org/10.1016/j.meegid.2018.02.017
- Sallas ML, Dos Santos MP, Orcini WA, David EB, Peruquetti RL, Payao SLM, et al. 2019. Status (on/off) of oipA gene: their associations with gastritis and gastric cancer and geographic origins. Arch. Microbiol. 201: 93-97. https://doi.org/10.1007/s00203-018-1580-5
- Torres K, Valderrama E, Sayegh M, Ramirez JL, Chiurillo MA. 2014. Study of the oipA genetic diversity and EPIYA motif patterns in cagA-positive Helicobacter pylori strains from Venezuelan patients with chronic gastritis. Microb. Pathog. 76: 26-32. https://doi.org/10.1016/j.micpath.2014.09.006
- Lehours P, Menard A, Dupouy S, Bergey B, Richy F, Zerbib F, et al. 2004. Evaluation of the association of nine Helicobacter pylori virulence factors with strains involved in low-grade gastric mucosa-associated lymphoid tissue lymphoma. Infect. Immun. 72: 880-888. https://doi.org/10.1128/IAI.72.2.880-888.2004
- Yamaoka Y, Ojo O, Fujimoto S, Odenbreit S, Haas R, Gutierrez O, et al. 2006. Helicobacter pylori outer membrane proteins and gastroduodenal disease. Gut 55: 775-781. https://doi.org/10.1136/gut.2005.083014
- Yanai A, Maeda S, Hikiba Y, Shibata W, Ohmae T, Hirata Y, et al. 2007. Clinical relevance of Helicobacter pylori sabA genotype in Japanese clinical isolates. J. Gastroenterol. Hepatol. 22: 2228-2232. https://doi.org/10.1111/j.1440-1746.2007.04831.x
- Kidd M, Peek R, Lastovica A, Israel D, Kummer A, Louw J. 2001. Analysis of iceA genotypes in South African Helicobacter pylori strains and relationship to clinically significant disease. Gut 49: 629-635. https://doi.org/10.1136/gut.49.5.629
- Lu H, Graham DY, Yamaoka Y. 2004. The Helicobacter pylori restriction endonuclease-replacing gene, hrgA, and clinical outcome: comparison of East Asia and Western countries. Dig. Dis. Sci. 49: 1551-1555. https://doi.org/10.1023/B:DDAS.0000042263.18541.ec
- Yakoob J, Abbas Z, Khan R, Salim SA, Abrar A, Awan S, et al. 2015. Helicobacter pylori: correlation of the virulence marker iceA allele with clinical outcome in a high prevalence area. Br. J. Biomed. Sci. 72: 67-73. https://doi.org/10.1080/09674845.2015.11666799
- Ashour AAR, Collares GB, Mendes EN, de Gusmao VrR, de Magalhaes Queiroz DM, Magalhaes PP, et al. 2001. iceA genotypes of Helicobacter pylori strains isolated from Brazilian children and adults. J. Clin. Microbiol. 39: 1746-1750. https://doi.org/10.1128/JCM.39.5.1746-1750.2001
- Sgouras DN, Trang TTH, Yamaoka Y. 2015. Pathogenesis of Helicobacter pylori infection. Helicobacter 20: 8-16. https://doi.org/10.1111/hel.12251
- Argent RH, Burette A, Miendje Deyi VY, Atherton JC. 2007. The presence of dupA in Helicobacter pylori is not significantly associated with duodenal ulceration in Belgium, South Africa, China, or North America. Clin. Infect. Dis. 45: 1204-1206. https://doi.org/10.1086/522177
- Hussein N. 2010. The association of dupA and Helicobacter pylori-related gastroduodenal diseases. Eur. J. Clin. Microbiol. Infect. Dis. 29: 817-821. https://doi.org/10.1007/s10096-010-0933-z
- Shiota S, Matsunari O, Watada M, Hanada K, Yamaoka Y. 2010. Systematic review and meta-analysis: the relationship between the Helicobacter pylori dupA gene and clinical outcomes. Gut Pathog. 2: 13. https://doi.org/10.1186/1757-4749-2-13
- Pacheco A, Proenca-Modena J, Sales A, Fukuhara Y, Da Silveira W, Pimenta-Modena J, et al. 2008. Involvement of the Helicobacter pylori plasticity region and cag pathogenicity island genes in the development of gastroduodenal diseases. Eur. J. Clin. Microbiol. Infect. Dis. 27: 1053-1059. https://doi.org/10.1007/s10096-008-0549-8
- Nguyen L, Uchida T, Tsukamoto Y, Kuroda A, Okimoto T, Kodama M, et al. 2010. Helicobacter pylori dupA gene is not associated with clinical outcomes in the Japanese population. Clin. Microbiol. Infect. 16: 1264-1269. https://doi.org/10.1111/j.1469-0691.2009.03081.x
- Kim JW, Kim JG, Chae SL, Cha YJ, Park SM. 2004. High prevalence of multiple strain colonization of Helicobacter pylori in Korean patients: DNA diversity among clinical isolates from the gastric corpus, antrum and duodenum. Korean. J. Intern. Med. 19: 1-9. https://doi.org/10.3904/kjim.2004.19.1.1
- dos Santos Silva I. 1999. Cancer epidemiology: principles and methods, pp. 305-331. Renouf Pub Co Ltd, Lyon, France.
- Yamaoka Y, El-Zimaity HMT, Gutierrez O, Figura N, Kim JK, Kodama T, et al. 1999. Relationship between the cagA3 repeat region of Helicobacter pylori, gastric histology, and susceptibility to low pH. Gastroenterology 117: 342-349. https://doi.org/10.1053/gast.1999.0029900342
- Atherton JC, Cao P, Peek RM, Tummuru MKR, Blaser MJ, Cover TL. 1995. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori: association of specific vacA types with cytotoxin production and peptic ulceration. J. Biol. Chem. 270: 17771-17777. https://doi.org/10.1074/jbc.270.30.17771
- Rhead JL, Letley DP, Mohammadi M, Hussein N, Mohagheghi MA, Hosseini ME, et al. 2007. A new Helicobacter pylori vacuolating cytotoxin determinant, the intermediate region, is associated with gastric cancer. Gastroenterology 133: 926-936. https://doi.org/10.1053/j.gastro.2007.06.056
- Rokbi B, Seguin D, Guy B, Mazarin V, Vidor E, Mion F, et al. 2001. Assessment of Helicobacter pylori gene expression within mouse and human gastric mucosae by real-time reverse transcriptase PCR. Infect. Immun. 69: 4759-4766. https://doi.org/10.1128/IAI.69.8.4759-4766.2001
- Yamaoka Y, Kwon DH, Graham DY. 2000. A Mr 34,000 proinflammatory outer membrane protein (oipA) of Helicobacter pylori. Proc. Natl. Acad. Sci. USA 97: 7533-7538. https://doi.org/10.1073/pnas.130079797
- Peck B, Ortkamp M, Diehl KD, Hundt E, Knapp B. 1999. Conservation, localization and expression of HopZ, a protein involved in adhesion of Helicobacter pylori. Nucleic Acids Res. 27: 3325-3333. https://doi.org/10.1093/nar/27.16.3325
- De Jonge R, Pot RGJ, Loffeld RJLF, Van Vliet AHM, Kuipers EJ, Kusters JG. 2004. The functional status of the Helicobacter pylori sabB adhesin gene as a putative marker for disease outcome. Helicobacter 9: 158-164. https://doi.org/10.1111/j.1083-4389.2004.00213.x
- Mukhopadhyay AK, Kersulyte D, Jeong JY, Datta S, Ito Y, Chowdhury A, et al. 2000. Distinctiveness of genotypes of Helicobacter pylori in Calcutta, India. J. Bacteriol. 182: 3219-3227. https://doi.org/10.1128/JB.182.11.3219-3227.2000
- Ando T, Wassenaar TM, Peek RM, Aras RA, Tschumi AI, van Doorn L-J, et al. 2002. A Helicobacter pylori restriction endonuclease-replacing gene, hrgA, is associated with gastric cancer in Asian strains. Cancer Res. 62: 2385-2389.