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Dystrophic Extra-Articular Soft Tissue Calcification after Burn Injury: A Case Study and Literature Review

화상 후 발생한 관절외 연조직의 이영양성 석회침착: 문헌조사 및 증례보고

  • Yun, In-Sik (Department of Plastic & Reconstructive Surgery, Yonsei University College of Medicine) ;
  • Lee, Sang-Soo (Department of Plastic & Reconstructive Surgery, Yonsei University College of Medicine) ;
  • Jeon, Yeo-Reum (Department of Plastic and Reconstructive Surgery, National Health Insurance Service, Ilsan Hospital) ;
  • Chung, Seum (Department of Plastic and Reconstructive Surgery, National Health Insurance Service, Ilsan Hospital) ;
  • Song, Joon-Ho (Department of Plastic and Reconstructive Surgery, National Health Insurance Service, Ilsan Hospital)
  • 윤인식 (연세대학교 의과대학 성형외과학교실) ;
  • 이상수 (연세대학교 의과대학 성형외과학교실) ;
  • 전여름 (국민건강보험 일산병원 성형외과학교실) ;
  • 정섬 (국민건강보험 일산병원 성형외과학교실) ;
  • 송준호 (국민건강보험 일산병원 성형외과학교실)
  • Received : 2021.06.03
  • Accepted : 2021.08.18
  • Published : 2021.12.31

Abstract

Soft tissue calcifications after burn injuries are commonly found in the periarticular region. They can easily be found because they cause severe pain and distress to the patient. However, a long period is required to identify extra-articular soft tissue calcification after burn injuries because they have no specific symptoms. Herein, we present the case of a patient with dystrophic extra-articular soft tissue calcification after a burn injury. A 70-year-old woman developed a non-healing ulcer in the right lower leg area two months before presentation to the hospital. She had third-degree flame burns on the anteromedial tibial area of the right leg approximately 40 years prior, and there had been no particular problem. Examination revealed chronic ulcers, and a review of radiograph findings revealed irregular calcification. The wound was treated with wide excision with a skin graft, and it healed without complications. During follow-up one month later, no recurrence of the calcification or ulceration of the lesion was found.

Keywords

Acknowledgement

No benefits in any form have been received or will be received from any commercial party related directly or in directly to the subject of this article.

References

  1. Kornhaber R, Foster N, Edgar D, Visentin D, Ofir E, Haik J, et al. The development and impact of heterotopic ossification in burns: a review of four decades of research. Scars Burn Heal 2017 Doi: 10.1177/2059513117695659.
  2. Moon YJ, Jeong SY, Lee KB. Extra-articular soft-tissue calcification after burn injury: a case study. J Burn Care Res 2018;39:835-7. https://doi.org/10.1097/BCR.0000000000000616
  3. Ebrahim MK, Kanjoor JR, Bang RL. Heterotopic calcification in burn scars and non-healing ulcers. Burns 2003;29:461-8. https://doi.org/10.1016/S0305-4179(03)00057-3
  4. Copcu E. Marjolin's ulcer: a preventable complication of burns? Plast Reconstr Surg 2009;124:156e-64e. https://doi.org/10.1097/PRS.0b013e3181a8082e
  5. Kang SG, Lee JW, Ko JH, Seo DK, Choi JK, Jang YC. Treatment of heterotopic calcification with ulceration in burn scar. Arch Plast Surg 2010;37:415-420.
  6. Walsh JS, Fairley JA. Calcifying disorders of the skin. J Am Acad Dermatol 1995;33:693-706. https://doi.org/10.1016/0190-9622(95)91803-5
  7. Boulman N, Slobodin G, Rozenbaum M, Rosner I. Calcinosis in rheumatic diseases. Semin Arthritis Rheum 2005;34:805-812. https://doi.org/10.1016/j.semarthrit.2005.01.016
  8. Lee SY, Kim KS, Kim DY, et al. Dystrophic calcinosis cutis in a patient with squamous cell carcinoma secondary to postburn scar. Ann Plast Surg 2001;46:457-8. https://doi.org/10.1097/00000637-200104000-00024
  9. Ramirez DM, Ramirez MR, Reginato AM, Medici D. Molecular and cellular mechanisms of heterotopic ossification. Histol Histopathol 2014;29:1281-5.
  10. Grenier G, Leblanc E, Faucheux N, Lauzier D, Kloen P, Hamdy RC. BMP-9 expression in human traumatic heterotopic ossification: a case report. Skelet Muscle 2013;3:1-6. https://doi.org/10.1186/2044-5040-3-1