Animal Bioscience

Asian Australasian Association of Animal Production Societies (아세아태평양축산학회)
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Postpartum prostaglandin F2α administration affects colostrum yield, immunoglobulin G, and piglet performance

  • Maneetong, Photcharaphan (Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University) ;
  • Srisang, Chutikan (Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University) ;
  • Sunanta, Naritsara (Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University) ;
  • Muchalintamolee, Praeploy (Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University) ;
  • Pearodwong, Pachara (School of Agricultural Resources, Chulalongkorn University) ;
  • Suwimonteerabutr, Junpen (Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University) ;
  • Rensis, Fabio De (Department of Veterinary Medical Science, University of Parma) ;
  • Tummaruk, Padet (Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University)
  • Received : 2020.03.25
  • Accepted : 2020.09.03
  • Published : 2021.05.01
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Abstract

Objective: Current study was conducted to determine the effect of postpartum prostaglandin F2α (PGF2α) administration on colostrum and milk yield, colostrum immunoglobulin G (IgG) and piglet growth performance. Methods: In total, 36 sows were included in the experiment. The sows were classified into two groups: i) control (n = 11) and ii) PGF2α (n = 25). Sows in the PGF2α group received 10 mg of PGF2α within an hour after farrowing. The body weight of piglets was measured at 0 and 24 h after birth to estimate colostrum consumption. Colostrum was collected at 1 and 24 h after farrowing to determine IgG concentrations. For milk yield study, the remaining sows in the PGF2α group (n = 23) were divided into two subgroups: i) single PGF2α (n = 12) and ii) multiple PGF2α (n = 11). In the multiple PGF2α, the sows received repeated doses of PGF2α at seven and 14 days postpartum. The piglets' body weight was measured at 0, 1, 5, and 20 days of age. The milk yield of the sows was calculated. Results: Colostrum yield of sows averaged 5.62±2.25 kg. Sows treated with PGF2α postpartum had a higher colostrum yield than control (7.01 and 5.12 kg, p<0.05). The concentration of IgG in colostrum at 24 h in the PGF2α group was higher than the control (31.6 and 17.4 g/L, p<0.05). For primiparous sows, milk yield was highest in the sows treated with multiple doses of PGF2α during lactation and lowest in control sows (10.25 and 7.61 kg, p<0.05). Colostrum intake was higher in the treatment than the control groups (+56.7 g, p<0.05). Primiparous sows treated with multiple doses of PGF2α had a higher litter weight than controls (p<0.01). Conclusion: Postpartum treatment with PGF2α improved colostrum yield and IgG in multiparous sows and increased colostrum intake of piglets. Multiple administration of PGF2α improved the milk yield and increased litter weight of piglets in primiparous sows.

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References

  1. Nuntapaitoon M, Muns R, Theil PK, Tummaruk P. Factors influencing colostrum consumption by piglets and their relationship with survival and growth in tropical climates. Livest Sci 2019;224:31-9. https://doi.org/10.1016/j.livsci.2019.04.008
  2. Quesnel H, Farmer C, Devillers N. Colostrum intake: influence on piglet performance and factors of variation. Livest Sci 2012;146:105-14. https://doi.org/10.1016/j.livsci.2012.03.010
  3. Alvarenga ALN, Chiarini-Garcia H, Cardeal PC, et al. Intrauterine growth retardation affects birthweight and postnatal development in pigs, impairing muscle accretion, duodenal mucosa morphology and carcass traits. Reprod Fertil Dev 2012;25:387-95. https://doi.org/10.1071/RD12021
  4. Udomchanya J, Suwannutsiri A, Sripantabut K, et al. Association between the incidence of stillbirths and expulsion interval, piglet birth weight, litter size and carbetocin administration in hyper-prolific sows. Livest Sci 2019;227:12834. https://doi.org/10.1016/j.livsci.2019.07.013
  5. Muns R, Manzanilla EG, Sol C, Manteca X, Gasa J. Piglet behavior as a measure of vitality and its influence on piglet survival and growth during lactation. J Anim Sci 2013;91: 1838-43. https://doi.org/10.2527/jas.2012-5501
  6. De Rensis F, Saleri R, Tummaruk P, Techakumphu M, Kirkwood RN. Prostaglandin F2α and control of reproduction in female swine: a review. Theriogenology 2012;77:1-11. https://doi.org/10.1016/j.theriogenology.2011.07.035
  7. Boonraungrod N, Sutthiya N, Kumwan P, et al. Control of parturition in swine using PGF2α in combination with carbetocin. Livest Sci 2018;214:1-8. https://doi.org/10.1016/j.livsci.2018.05.012
  8. Tospitakkul P, Kraomkaew K, Thammasin K, et al. Induction of parturition by double administration of prostaglandin F2alpha in sows reduces the variation of gestation length without affecting the colostrum yield and piglet performance. J Vet Med Sci 2019;81:1334-40. https://doi.org/10.1292/jvms.18-0725
  9. Vanderhaeghe C, Dewulf J, Daems A, Van Soom A, De Kruif A, Maes D. Influence of postpartum cloprostenol treatment in sows on subsequent reproductive performance under field conditions. Reprod Domest Anim 2008;43:484-9. https://doi.org/10.1111/j.1439-0531.2007.00942.x
  10. Dubuc J, Duffield TF, Leslie KE, Walton JS, LeBlanc SJ. Randomized clinical trial of antibiotic and prostaglandin treatments for uterine health and reproductive performance in dairy cows. J Dairy Sci 2011;94:1325-38. https://doi.org/10.3168/jds.2010-3757
  11. Borchardt S, Ludwig S, Heuwieser W. Randomized clinical trial to evaluate the efficacy of prostaglandin F2α to treat purulent vaginal discharge in lactating dairy cows. J Dairy Sci 2018;101:11403-12. https://doi.org/10.3168/jds.201814765
  12. Hansen AV, Strathe AB, Kebreab E, France J, Theil PK. Predicting milk yield and composition in lactating sows: a Bayesian approach. J Anim Sci 2012;90:2285-98. https://doi.org/10.2527/jas.2011-4788
  13. Nuntapaitoon M, Suwimonteerabutr J, Am-in N, et al. Impact of parity and housing conditions on concentration of immunoglobulin G in sow colostrum. Trop Anim Health Prod 2019;51:1239-46. https://doi.org/10.1007/s11250-019-01816-2
  14. Theil PK, Flummer C, Hurley WL, Kristensen NB, Labouriau RL, Sorensen MT. Mechanistic model to predict colostrum intake based on deuterium oxide dilution technique data and impact of gestation and prefarrowing diets on piglet intake and sow yield of colostrum. J Anim Sci 2014;92:5507-19. https://doi.org/10.2527/jas.2014-7841
  15. SAS Institute Inc. SAS user's guide. Statistics version 9.4. Cary, NC, USA: SAS Institute Inc; 2014.
  16. Quesnel H. Colostrum production by sows: variability of colostrum yield and immunoglobulin G concentrations. Animal 2011;5:1546-53. https://doi.org/10.1017/S175173111100070X
  17. Declerck I, Dewulf J, Sarrazin S, Maes D. Long-term effects of colostrum intake in piglet mortality and performance. J Anim Sci 2016;94:1633-43. https://doi.org/10.2527/jas.20159564
  18. Vadmand CN, Krogh U, Hansen CF, Theil PK. Impact of sow and litter characteristics on colostrum yield, time for onset of lactation, and milk yield of sows. J Anim Sci 2015;93: 2488-500. https://doi.org/10.2527/jas.2014-8659
  19. Hasan S, Orro T, Valros A, Junnikkala S, Peltoniemi O, Oliviero C. Factors affecting sow colostrum yield and composition, and their impact on piglet growth and health. Livest Sci 2019; 227:60-7. https://doi.org/10.1016/j.livsci.2019.07.004
  20. Izeta-Mayorga J, Terminal O, Soto M, Ramos R, Ramirez F. PGF2α (dinoprost tromethamine) 24 hrs post-farrowing and its effects on the weaning to service interval, fertility and the effects of antibiotic treatments in sows of different parities. In: Proceedings of the 15th IPVS Congress 1988; Birmingham, England. pp. 89.
  21. Morrow WM, Britt J, Belschner A, Neeley G, O'Carroll J. Effect of injecting sows with prostaglandin F2α immediately postpartum on subsequent reproductive performance. Swine Health Prod 1996;4:73-8.
  22. Algers B, Uvnas-Moberg K. Maternal behavior in pigs. Horm Behav 2007;52:78-85. https://doi.org/10.1016/j.yhbeh.2007.03.022
  23. Declerck I, Sarrazin S, Dewulf J, Maes D. Sow and piglet factors determining variation of colostrum intake between and within litters. Animal 2017;11:1336-43. https://doi.org/10.1017/S1751731117000131
  24. Markowska-Daniel I, Pomorska-Mol M. Shifts in immunoglobulins levels in the porcine mammary secretions during whole lactation period. Bull Vet Inst Pulawy 2010;54;345-9.
  25. Farmer C, Quesnel H. Nutritional, hormonal, and environmental effects on colostrum in sows. J Anim Sci 2009;87(Suppl 13):56-64. https://doi.org/10.2527/jas.2008-1203
  26. Devillers N, Le Dividich J, Prunier A. Influence of colostrum intake on piglet survival and immunity. Animal 2011;5:1605-12. https://doi.org/10.1017/S175173111100067X
  27. Hasan SMK, Junnikkala S, Valros A, Peltoniemi O, Oliviero C. Validation of Brix refractometer to estimate colostrum immunoglobulin G content and composition in the sow. Animal 2016;10:1728-33. https://doi.org/10.1017/S1751731116000896
  28. Tarrier MP, Kattesh HG, Gillespie BE. Progesterone levels and litter performance of sows following postpartum administration of prostaglandin F2α. Theriogenology 1989;31:3938. https://doi.org/10.1016/0093-691X(89)90545-1
  29. de Passille AM, Rushen J, Foxcroft GR, Aherne FX, Schaefer A. Performance of young pigs: relationships with periparturient progesterone, prolactin, and insulin of sows. J Anim Sci 1993;71:179-84. https://doi.org/10.2527/1993.711179x
  30. Miller HM, Foxcroft GR, Aherne FX. Increasing feed intake in late gestation does not affect plasma progesterone concentration in the sow. Theriogenology 2004;62:1618-26. https://doi.org/10.1016/j.theriogenology.2004.03.002
  31. Hillbrand FW, Elsaesser F. Concentrations of progesterone in the backfat of pigs during the oestrous cycle and after ovariectomy. J Reprod Fertil 1983;69:73-80. https://doi.org/10.1530/jrf.0.0690073