Journal of Veterinary Science

The Korean Society of Veterinary Science (대한수의학회)
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Genetic characterization of H9N2 avian influenza virus previously unrecognized in Korea

  • Heo, Gyeong-Beom (Avian Influenza Research & Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Kye, Soo-Jeong (Avian Influenza Research & Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Sagong, Mingeun (Avian Influenza Research & Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Lee, Eun-Kyoung (Avian Influenza Research & Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Lee, Kwang-Nyeong (Avian Influenza Research & Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Lee, Yu-Na (Avian Influenza Research & Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Choi, Kang-Seuk (College of Veterinary Medicine, Seoul National University) ;
  • Lee, Myoung-Heon (Avian Influenza Research & Diagnostic Division, Animal and Plant Quarantine Agency) ;
  • Lee, Youn-Jeong (Avian Influenza Research & Diagnostic Division, Animal and Plant Quarantine Agency)
  • Received : 2020.09.01
  • Accepted : 2021.01.25
  • Published : 2021.03.31
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Abstract

In this study, we describe the isolation and characterization of previously unreported Y280-lineage H9N2 viruses from two live bird markets in Korea in June 2020. Genetic analysis revealed that they were distinct from previous H9N2 viruses circulating in Korea and had highest homology to A/chicken/Shandong/1844/2019(H9N2) viruses. Their genetic constellation showed they belonged to genotype S, which is the predominant genotype in China since 2010, where genotype S viruses have infected humans and acted as internal gene donors to H5 and H7 zoonotic influenza viruses. Active surveillance and control measures need to be enhanced to protect the poultry industry and public health.

Keywords

Acknowledgement

We thank Eun-bi Noh, Jeong-Eui Lee, In-Kyeong Kim, and Byeong-suk Jeon for excellent technical assistance. We also thank the Animal and Plant Quarantine Agency, Ministry of Agriculture, Food and Rural Affairs, and the Regional Office for Animal Disease Control for their efforts to control AIV. We thank our colleagues worldwide for their laboratory contributions, which were made available through GISAID and GenBank.

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