Journal of Veterinary Science

  • 제22권1호
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  • Pages.2.1-2.10
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  • 2021
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  • 1229-845X(pISSN)
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  • 1976-555X(eISSN)
대한수의학회 (The Korean Society of Veterinary Science)
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Cerebrospinal fluid flow in normal beagle dogs analyzed using magnetic resonance imaging

  • Cho, Hyunju (Research Institute of Veterinary Medicine, College of Veterinary Medicine, Chungnam National University) ;
  • Kim, Yejin (Research Institute of Veterinary Medicine, College of Veterinary Medicine, Chungnam National University) ;
  • Hong, Saebyel (Research Institute of Veterinary Medicine, College of Veterinary Medicine, Chungnam National University) ;
  • Choi, Hojung (Research Institute of Veterinary Medicine, College of Veterinary Medicine, Chungnam National University)
  • 투고 : 2020.09.08
  • 심사 : 2020.11.05
  • 발행 : 2021.01.31
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초록

Background: Diseases related to cerebrospinal fluid flow, such as hydrocephalus, syringomyelia, and Chiari malformation, are often found in small dogs. Although studies in human medicine have revealed a correlation with cerebrospinal fluid flow in these diseases by magnetic resonance imaging, there is little information and no standard data for normal dogs. Objectives: The purpose of this study was to obtain cerebrospinal fluid flow velocity data from the cerebral aqueduct and subarachnoid space at the foramen magnum in healthy beagle dogs. Methods: Six healthy beagle dogs were used in this experimental study. The dogs underwent phase-contrast and time-spatial labeling inversion pulse magnetic resonance imaging. Flow rate variations in the cerebrospinal fluid were observed using sagittal time-spatial labeling inversion pulse images. The pattern and velocity of cerebrospinal fluid flow were assessed using phase-contrast magnetic resonance imaging within the subarachnoid space at the foramen magnum level and the cerebral aqueduct. Results: In the ventral aspect of the subarachnoid space and cerebral aqueduct, the cerebrospinal fluid was characterized by a bidirectional flow throughout the cardiac cycle. The mean ± SD peak velocities through the ventral and dorsal aspects of the subarachnoid space and the cerebral aqueduct were 1.39 ± 0.13, 0.32 ± 0.12, and 0.76 ± 0.43 cm/s, respectively. Conclusions: Noninvasive visualization of cerebrospinal fluid flow movement with magnetic resonance imaging was feasible, and a reference dataset of cerebrospinal fluid flow peak velocities was obtained through the cervical subarachnoid space and cerebral aqueduct in healthy dogs.

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과제정보

This work was supported by research fund of Chungnam National University.

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