Acknowledgement
We would like to thank the team at the Infection Control Center of SNUBH for their support and providing CLABSI-surveillance data in this analysis.
References
- Menon G. Neonatal long lines. Arch Dis Child Fetal Neonatal Ed 2003;88:F260-2. https://doi.org/10.1136/fn.88.4.F260
- Erdei C, McAvoy LL, Gupta M, Pereira S, McGowan EC. Is zero central line-associated bloodstream infection rate sustainable? A 5-year perspective. Pediatrics 2015;135:e1485-93. https://doi.org/10.1542/peds.2014-2523
- Goudie A, Dynan L, Brady PW, Rettiganti M. Attributable cost and length of stay for central lineassociated bloodstream infections. Pediatrics 2014;133:e1525-32. https://doi.org/10.1542/peds.2013-3795
- Karagiannidou S, Zaoutis T, Maniadakis N, Papaevangelou V, Kourlaba G. Attributable length of stay and cost for pediatric and neonatal central line-associated bloodstream infections in Greece. J Infect Public Health 2019;12:372-9. https://doi.org/10.1016/j.jiph.2018.12.004
- Couto RC, Carvalho EA, Pedrosa TM, Pedroso ER, Neto MC, Biscione FM. A 10-year prospective surveillance of nosocomial infections in neonatal intensive care units. Am J Infect Control 2007;35:183-9. https://doi.org/10.1016/j.ajic.2006.06.013
- Sengupta A, Lehmann C, Diener-West M, Perl TM, Milstone AM. Catheter duration and risk of CLA-BSI in neonates with PICCs. Pediatrics 2010;125:648-53. https://doi.org/10.1542/peds.2009-2559
- Milstone AM, Reich NG, Advani S, Yuan G, Bryant K, Coffin SE, et al. Catheter dwell time and CLABSIs in neonates with PICCs: a multicenter cohort study. Pediatrics 2013;132:e1609-15. https://doi.org/10.1542/peds.2013-1645
- Sanderson E, Yeo KT, Wang AY, Callander I, Bajuk B, Bolisetty S, et al.NICUS Network. Dwell time and risk of central-line-associated bloodstream infection in neonates. J Hosp Infect 2017;97:267-74. https://doi.org/10.1016/j.jhin.2017.06.023
- Greenberg RG, Cochran KM, Smith PB, Edson BS, Schulman J, Lee HC, et al. Effect of catheter dwell time on risk of central line-associated bloodstream infection in infants. Pediatrics 2015;136:1080-6. https://doi.org/10.1542/peds.2015-0573
- American Academy of Pediatrics Committee on Fetus and Newborn. Levels of neonatal care. Pediatrics 2012;130:587-97. https://doi.org/10.1542/peds.2012-1999
- Kwak YG, Lee SO, Kim HY, Kim YK, Park ES, Jin HY, et al. Risk factors for device-associated infection related to organisational characteristics of intensive care units: findings from the Korean Nosocomial Infections Surveillance System. J Hosp Infect 2010;75:195-9. https://doi.org/10.1016/j.jhin.2010.01.014
- Huebner J, Goldmann DA. Coagulase-negative staphylococci: role as pathogens. Annu Rev Med 1999;50:223-36. https://doi.org/10.1146/annurev.med.50.1.223
- Lake JG, Weiner LM, Milstone AM, Saiman L, Magill SS, See I. Pathogen distribution and antimicrobial resistance among pediatric healthcare-associated infections reported to the National Healthcare Safety Network, 2011-2014. Infect Control Hosp Epidemiol 2018;39:1-11. https://doi.org/10.1017/ice.2017.236
- Hsu JF, Tsai MH, Huang HR, Lien R, Chu SM, Huang CB. Risk factors of catheter-related bloodstream infection with percutaneously inserted central venous catheters in very low birth weight infants: a center's experience in Taiwan. Pediatr Neonatol 2010;51:336-42. https://doi.org/10.1016/S1875-9572(10)60065-4
- Chun P, Kong SG, Byun SY, Park SE, Lee HD. Analysis of neonatal sepsis in one neonatal intensive care unit for 6 years. Korean J Pediatr 2010;53:495-502. https://doi.org/10.3345/kjp.2010.53.4.495
- Schulman J, Dimand RJ, Lee HC, Duenas GV, Bennett MV, Gould JB. Neonatal intensive care unit antibiotic use. Pediatrics 2015;135:826-33. https://doi.org/10.1542/peds.2014-3409
- Patel SJ, Green N, Clock SA, Paul DA, Perlman JM, Zaoutis T, et al. Gram-negative bacilli in infants hospitalized in the neonatal intensive care unit. J Pediatric Infect Dis Soc 2017;6:227-30.
- Almuneef MA, Baltimore RS, Farrel PA, Reagan-Cirincione P, Dembry LM. Molecular typing demonstrating transmission of Gram-negative rods in a neonatal intensive care unit in the absence of a recognized epidemic. Clin Infect Dis 2001;32:220-7. https://doi.org/10.1086/318477
- Folgori L, Tersigni C, Hsia Y, Kortsalioudaki C, Heath P, Sharland M, et al. The relationship between Gram-negative colonization and bloodstream infections in neonates: a systematic review and metaanalysis. Clin Microbiol Infect 2018;24:251-7. https://doi.org/10.1016/j.cmi.2017.08.008
- Stoll BJ, Hansen N, Fanaroff AA, Wright LL, Carlo WA, Ehrenkranz RA, et al. Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network. Pediatrics 2002;110:285-91. https://doi.org/10.1542/peds.110.2.285
- Gullberg E, Cao S, Berg OG, Ilback C, Sandegren L, Hughes D, et al. Selection of resistant bacteria at very low antibiotic concentrations. PLoS Pathog 2011;7:e1002158. https://doi.org/10.1371/journal.ppat.1002158
- Benjamin DK Jr, Stoll BJ, Gantz MG, Walsh MC, Sanchez PJ, Das A, et al. Neonatal candidiasis: epidemiology, risk factors, and clinical judgment. Pediatrics 2010;126:e865-73. https://doi.org/10.1542/peds.2009-3412
- Hanna Pharm M, Mazkereth R. Which patient in the neonatal intensive care unit should receive antifungal prophylaxis therapy? Isr Med Assoc J 2021;23:116-20.
- O'Grady NP, Alexander M, Burns LA, Dellinger EP, Garland J, Heard SO, et al. Guidelines for the prevention of intravascular catheter-related infections. Clin Infect Dis 2011;52:e162-93. https://doi.org/10.1093/cid/cir257
- Chien LY, Macnab Y, Aziz K, Andrews W, McMillan DD, Lee SK, et al. Variations in central venous catheter-related infection risks among Canadian neonatal intensive care units. Pediatr Infect Dis J 2002;21:505-11. https://doi.org/10.1097/00006454-200206000-00006
- Hoang V, Sills J, Chandler M, Busalani E, Clifton-Koeppel R, Modanlou HD. Percutaneously inserted central catheter for total parenteral nutrition in neonates: complications rates related to upper versus lower extremity insertion. Pediatrics 2008;121:e1152-9. https://doi.org/10.1542/peds.2007-1962
- Perlman SE, Saiman L, Larson EL. Risk factors for late-onset health care-associated bloodstream infections in patients in neonatal intensive care units. Am J Infect Control 2007;35:177-82. https://doi.org/10.1016/j.ajic.2006.01.002
- Mermel LA, Allon M, Bouza E, Craven DE, Flynn P, O'Grady NP, et al. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America. Clin Infect Dis 2009;49:1-45. https://doi.org/10.1086/599376
- Marschall J, Mermel LA, Fakih M, Hadaway L, Kallen A, O'Grady NP, et al. Strategies to prevent central line-associated bloodstream infections in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol 2014;35 Suppl 2:S89-107. https://doi.org/10.1017/S0899823X00193870