과제정보
This study was supported by the National Research Foundation of Korea (NRF) funded by the Korean Government (MIST) (NRF-2020R1F1A1075611).
참고문헌
- World Health Organization. Obesity and overweight. Geneva; 2020.
- Kahn BB, Flier JS. Obesity and insulin resistance. J Clin Invest 2000; 106(4): 473-481. https://doi.org/10.1172/JCI10842
- Petersen KF, Dufour S, Savage DB, Bilz S, Solomon G, Yonemitsu S, et al. The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome. Proc Natl Acad Sci U S A 2007; 104(31):12587-12594. https://doi.org/10.1073/pnas.0705408104
- Fukunaka A, Fujitani Y. Role of zinc homeostasis in the pathogenesis of diabetes and obesity. Int J Mol Sci 2018; 19(2): 476. https://doi.org/10.3390/ijms19020476
- Vallee BL, Falchuk KH. The biochemical basis of zinc physiology. Physiol Rev 1993; 73(1): 79-118. https://doi.org/10.1152/physrev.1993.73.1.79
- Baltaci AK, Yuce K. Zinc transporter proteins. Neurochem Res 2018; 43(3): 517-530. https://doi.org/10.1007/s11064-017-2454-y
- Hara T, Takeda TA, Takagishi T, Fukue K, Kambe T, Fukada T. Physiological roles of zinc transporters: molecular and genetic importance in zinc homeostasis. J Physiol Sci 2017; 67(2): 283-301. https://doi.org/10.1007/s12576-017-0521-4
- de Luis DA, Pacheco D, Izaola O, Terroba MC, Cuellar L, Cabezas G. Micronutrient status in morbidly obese women before bariatric surgery. Surg Obes Relat Dis 2013; 9(2): 323-327. https://doi.org/10.1016/j.soard.2011.09.015
- El Dib R, Gameiro OL, Ogata MS, Modolo NS, Braz LG, Jorge EC, et al. Zinc supplementation for the prevention of type 2 diabetes mellitus in adults with insulin resistance. Cochrane Database Syst Rev 2015;(5): CD005525.
- Qi Y, Zhang Z, Liu S, Aluo Z, Zhang L, Yu L, et al. Zinc supplementation alleviates lipid and glucose metabolic disorders induced by a high-fat diet. J Agric Food Chem 2020; 68(18): 5189-5200. https://doi.org/10.1021/acs.jafc.0c01103
- Thoen RU, Barther NN, Schemitt E, Bona S, Fernandes S, Coral G, et al. Zinc supplementation reduces dietinduced obesity and improves insulin sensitivity in rats. Appl Physiol Nutr Metab 2019; 44(6): 580-586. https://doi.org/10.1139/apnm-2018-0519
- Myers SA, Nield A, Chew GS, Myers MA. The zinc transporter, Slc39a7 (Zip7) is implicated in glycaemic control in skeletal muscle cells. PLoS One 2013; 8(11): e79316. https://doi.org/10.1371/journal.pone.0079316
- Pruessner JC, Kirschbaum C, Meinlschmid G, Hellhammer DH. Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change. Psychoneuroendocrinology 2003; 28(7): 916-931. https://doi.org/10.1016/S0306-4530(02)00108-7
- Huang L, Tepaamorndech S, Kirschke CP, Newman JW, Keyes WR, Pedersen TL, et al. Aberrant fatty acid metabolism in skeletal muscle contributes to insulin resistance in zinc transporter 7 (znt7)-knockout mice. J Biol Chem 2018; 293(20): 7549-7563. https://doi.org/10.1074/jbc.M117.817692
- Norouzi S, Adulcikas J, Henstridge DC, Sonda S, Sohal SS, Myers S. The zinc transporter Zip7 is downregulated in skeletal muscle of insulin-resistant cells and in mice fed a high-fat diet. Cells 2019; 8(7): 663. https://doi.org/10.3390/cells8070663
- Min B, Chung J. Effects of high-fat diet induced obesity on tissue zinc concentrations and zinc transporter expressions in mice. J Nutr Health 2018; 51(6): 489-497. https://doi.org/10.4163/jnh.2018.51.6.489
- Kennedy ML, Failla ML, Smith JC Jr. Influence of genetic obesity on tissue concentrations of zinc, copper, manganese and iron in mice. J Nutr 1986; 116(8): 1432-1441. https://doi.org/10.1093/jn/116.8.1432
- Tsao TS, Li J, Chang KS, Stenbit AE, Galuska D, Anderson JE, et al. Metabolic adaptations in skeletal muscle overexpressing GLUT4: effects on muscle and physical activity. FASEB J 2001; 15(6): 958-969. https://doi.org/10.1096/fsb2fj000381
- Mnatsakanyan H, Serra RSI, Rico P, Salmeron-Sanchez M. Zinc uptake promotes myoblast differentiation via Zip7 transporter and activation of Akt signalling transduction pathway. Sci Rep 2018; 8(1): 13642. https://doi.org/10.1038/s41598-018-32067-0
- Taylor KM, Vichova P, Jordan N, Hiscox S, Hendley R, Nicholson RI. ZIP7-mediated intracellular zinc transport contributes to aberrant growth factor signaling in antihormone-resistant breast cancer cells. Endocrinology 2008; 149(10): 4912-4920. https://doi.org/10.1210/en.2008-0351
- Nimmanon T, Ziliotto S, Morris S, Flanagan L, Taylor KM. Phosphorylation of zinc channel ZIP7 drives MAPK, PI3K and mTOR growth and proliferation signalling. Metallomics 2017; 9(5): 471-481. https://doi.org/10.1039/c6mt00286b