한국식생활문화학회지 (Journal of the Korean Society of Food Culture)

  • 제36권6호
  • /
  • Pages.563-570
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  • 2021
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  • 1225-7060(pISSN)
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  • 2288-7148(eISSN)
한국식생활문화학회 (Korean Society of Food Culture)
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Effects of a Health Drink Containing the Extract of the Hovenia Dulcis Fruit Stalk and Theracurmin, on Ethanol-Induced Hangover

  • Kang, Nam E (Department of Food and Nutrition, Eulji University) ;
  • Oh, Yoon Sin (Department of Food and Nutrition, Eulji University) ;
  • Yeo, Hee Kyung (R&D center, HANDOK Inc.) ;
  • Baik, Hyun Wook (Department of Internal Medicine, Division of Gastroenterology & Clinical Nutrition, DMC Bundang Jesaeng Hospital) ;
  • Jang, Se-Eun (Department of Food and Nutrition, Eulji University)
  • 투고 : 2021.09.14
  • 심사 : 2021.11.29
  • 발행 : 2021.12.31
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초록

The fruit stalk of Hovenia dulcis (H.dulcis) is traditionally used to relieve hangovers in Korea. Theracurmin is a highly absorbable curcumin preparation which increases the bioavailability of curcumin. Curcumin is known for its antioxidant and anti-inflammatory effects. However, the role of this combination in lowering alcohol levels in the body, thereby alleviating the severity of alcohol-induced hangover has not been investigated. Therefore, we conducted a study to investigate the eliminatory effects of a health drink containing the extract of the H. dulcis fruit stalk and theracurmin (theracurmin drink) on ethanol-induced hangover in rats. The theracurmin drink delivered orally to rats 30 mins before the administration of 40% ethanol (5 g/kg body weight), lowered the concentration of ethanol and acetaldehyde in the blood samples collected 1, 3, and 5 h after ethanol administration. Furthermore, the theracurmin drink increased the activities of alcohol dehydrogenase and aldehyde dehydrogenase enzymes. The effectiveness of the theracurmin drink was thus superior to that of other health drink products, suggesting that its consumption may alleviate or prevent an alcohol-induced hangover.

키워드

과제정보

The present study was supported by a grant from Handok Pharmaceuticals in Korea.

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