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Flow Characteristics in a Human Airway model for Oral Cancer Surgery by PIV Experiment and Numerical Simulation

PIV 측정 및 수치해석을 이용한 구강암 수술에 따른 기도 형상 내 유동 특성

  • Hong, Hyeonji (Eco-friendly Smart Ship Parts Technology Innovation Center, PNU) ;
  • An, Se Hyeon (School of Mechanical Engineering, PNU) ;
  • Seo, Heerim (School of Mechanical Engineering, PNU) ;
  • Song, Jae Min (Department of Oral and Maxillofacial Surgery, School of Dentistry, PNU) ;
  • Yeom, Eunseop (School of Mechanical Engineering, Pusan National University (PNU))
  • Received : 2021.11.11
  • Accepted : 2021.12.21
  • Published : 2021.12.31

Abstract

Oral cancer surgery typically consists of resection of lesion, neck dissection and reconstruction, and it has an impact on the position of hyoid bone. Therefore, morphological change of airway can occur since the geometric parameter of airway is correlated with the hyoid bone. Airflow is affected by geometry of the airway. In this study, flow characteristics were compared between pre- and post-surgery models by both particle image velocimetry (PIV) and numerical simulation. 3D model of upper airway was reconstructed based on CT data. Velocity is accelerated by the reduced channel area, and vortex and recirculation region are observed in pre- and post-surgery models. For the post-surgery model, high pressure distribution is developed by significantly decreased hydraulic diameter, and the longitudinal flow stream is also interrupted.

Keywords

Acknowledgement

본 연구는 2021도 부산대학교 기계기술연구원 연구과제 (RIMT2021-01) 연구비지원으로 수행하였음

References

  1. Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A. and Bray, F., 2021, "Global Cancer Statistics 2020: Globocan Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries," CA Cancer J. Clin., Vol. 71, No. 3, pp. 209-249. https://doi.org/10.3322/caac.21660
  2. Paeng, J.-Y., Kim, J.-W. and Lee, S.-T., 2019, "Changes in Hyoid Bone Position and Cross-Sectional Area of Pharyngeal Airway after Oral Cancer Surgery," Anticancer Res., Vol. 39, No. 4, pp. 2097-2104. https://doi.org/10.21873/anticanres.13322
  3. Takahashi, Y., Minamikawa, T., Yonezawa, N., Komatsu, H., Nibu, K. and Komori, T., 2017, "Analysis of the Hyoid Motion of Tongue Cancer Patients," Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, Vol. 29, No. 2, pp. 105-109. https://doi.org/10.1016/j.ajoms.2016.09.007
  4. Jiang, Y. Y., 2016, "Correlation between Hyoid Bone Position and Airway Dimensions in Chinese Adolescents by Cone Beam Computed Tomography Analysis," Int. J. Oral Maxillofac. Surg., Vol. 45, No. 7, pp. 914-921. https://doi.org/10.1016/j.ijom.2016.02.005
  5. Becker, O. E., Avelar, R. L., Goelzer, J. G., Dolzan, A. d. N., Haas Junior, O. L. and De Oliveira, R. B., 2012, "Pharyngeal Airway Changes in Class Iii Patients Treated with Double Jaw Orthognathic Surgery-Maxillary Advancement and Mandibular Setback," Journal of Oral and Maxillofacial Surgery, Vol. 70, No. 11, pp. e639-e647. https://doi.org/10.1016/j.joms.2012.07.052
  6. Kelly, J. T., Prasad, A. K. and Wexler, A. S., 2000, "Detailed Flow Patterns in the Nasal Cavity," Journal of Applied Physiology, Vol. 89, No. 1, pp. 323-337. https://doi.org/10.1152/jappl.2000.89.1.323
  7. Phuong, N. L. and Ito, K., 2015, "Investigation of Flow Pattern in Upper Human Airway Including Oral and Nasal Inhalation by Piv and Cfd," Building and Environment, Vol. 94, No., pp. 504-515. https://doi.org/10.1016/j.buildenv.2015.10.002
  8. Kim, S. K. and Chung, S.-K., 2009, "Investigation on the Respiratory Airflow in Human Airway by Piv," Journal of visualization, Vol. 12, No. 3, pp. 259-266. https://doi.org/10.1007/BF03181864
  9. Song, J. M., Seo, H., Choi, N.-R., Yeom, E. and Kim, Y.-D., 2020, "Application of Computational Fluid Dynamics Analysis after Bimaxillary Orthognathic Surgery," Applied Sciences, Vol. 10, No. 5, pp. 1676. https://doi.org/10.3390/app10051676
  10. Yushkevich, P. A., Piven, J., Hazlett, H. C., Smith, R. G., Ho, S., Gee, J. C. and Gerig, G., 2006, "User-Guided 3d Active Contour Segmentation of Anatomical Structures: Significantly Improved Efficiency and Reliability," NeuroImage, Vol. 31, No. 3, pp. 1116-1128. https://doi.org/10.1016/j.neuroimage.2006.01.015
  11. Hong, H., Ji, H. S., Kim, H. D. and Kim, K. C., 2017, "Temporal and Spatial Flow Structures in a Simulated Vessel with Stenotic Lesion Using Time-Resolved Piv Technique," Journal of Visualization, Vol. 20, No. 4, pp. 833-845. https://doi.org/10.1007/s12650-017-0432-8
  12. Sheely, M. L., 1932, "Glycerol Viscosity Tables," Ind. Eng. Chem., Vol. 24, No. 9, pp. 1060-1064. https://doi.org/10.1021/ie50273a022
  13. Association, G. P. 1963, Physical Properties of Glycerine and Its Solutions; Glycerine Producers' Association.
  14. Haverkamp, H. C., Dempsey, J. A., Miller, J. D., Romer, L. M. and Eldridge, M. W., 2005, "Physiologic Responses to Exercise," Physiologic basis of respiratory disease, Vol., No., pp. 525-540.
  15. Beni, H. M., Aghaei, F. and Kamalipour, S., 2021, "Experimental Tracking and Numerical Mapping of Novel Coronavirus Micro-Droplet Deposition through Nasal Inhalation in the Human Respiratory System," Biomech. Model. Mechanobiol., Vol. 20, No. 3, pp. 1087-1100. https://doi.org/10.1007/s10237-021-01434-8
  16. Goldman, M. D., Grimby, G. and Mead, J., 1976, "Mechanical Work of Breathing Derived from Rib Cage and Abdominal Vp Partitioning," Journal of Applied Physiology, Vol. 41, No. 5, pp. 752-763. https://doi.org/10.1152/jappl.1976.41.5.752
  17. Xu, X., Wu, J., Weng, W. and Fu, M., 2020, "Investigation of Inhalation and Exhalation Flow Pattern in a Realistic Human Upper Airway Model by Piv Experiments and Cfd Simulations," Biomech. Model. Mechanobiol., Vol. 19, No. 5, pp. 1679-1695. https://doi.org/10.1007/s10237-020-01299-3
  18. Seo, H., Song, J. M. and Yeom, E., 2020, "Numerical Simulation of Air Flows in Human Upper Airway for Free Flap Reconstruction Following Resection Surgery in Oral Cancer Patients," Journal of the Korean Society of Visualization, Vol. 18, No. 3, pp. 96-102. https://doi.org/10.5407/JKSV.2020.18.3.096