Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
권호 표지
DOI QR코드

DOI QR Code

Massive lymphangiosarcoma in a dog: a case report

  • Seo, Min-Gyeong (Department of Veterinary Pathology, College of Veterinary Medicine, Gyeongsang National University) ;
  • Choi, Yeon-Woo (Metro Animal Hospital) ;
  • Jung, Dong-In (Department of Veterinary Pathology, College of Veterinary Medicine, Gyeongsang National University) ;
  • Lee, Hee Chun (Department of Veterinary Pathology, College of Veterinary Medicine, Gyeongsang National University) ;
  • Hong, Il-Hwa (Department of Veterinary Pathology, College of Veterinary Medicine, Gyeongsang National University)
  • Received : 2021.06.28
  • Accepted : 2021.10.14
  • Published : 2021.12.31
Download PDF
⟨ Previous Next ⟩

Abstract

A 12-year-old neutered male Golden Retriever presented with a progressively enlarging mass in the submandibular region. Histopathological diagnosis confirmed lymphangiosarcoma with metastasis to the liver and spleen. The pleomorphic neoplastic endothelial cells of the tumor grow directly on bundles of dermal collagen, forming numerous clefts and interconnecting channels that are devoid of conspicuous hematic elements. As lymphangiosarcoma is an uncommon malignant neoplasm, the number of previously reported cases and information of the tumor is limited. The present report describes the clinical history and histopathological diagnosis of a progressive lymphangiosarcoma in the submandibular region with metastases in a dog.

Keywords

References

  1. Meuten DJ. Tumors in Domestic Animals. 5th ed. pp. 163-164, John Wiley & Sons, Ames, 2017.
  2. Azevedo CN, Sterman AA, Stranahan LW, Taylor BM, Wiener DJ, Davidson JR, Russell KE. Pathologic and flow cytometric features of a case of canine ventral cervical lymphangiosarcoma. J Vet Diagn Invest 2020;32:476-480. https://doi.org/10.1177/1040638720917324
  3. Curran KM, Halsey CH, Worley DR. Lymphangiosarcoma in 12 dogs: a case series (1998-2013). Vet Comp Oncol 2016;14:181-190. https://doi.org/10.1111/vco.12087
  4. Diessler ME, Castellano MC, Massone AR, Portiansky EL, Allende MG, Idiart JR, Gimeno EJ. Cutaneous lymphangiosarcoma in a young dog: clinical, anatomopathological and lectinhistochemical description. J Vet Med A Physiol Pathol Clin Med 2003;50:452-456. https://doi.org/10.1046/j.1439-0442.2003.00573.x
  5. Maxie G. Jubb, Kennedy & Palmer's Pathology of Domestic Animals, Volume 1. 6th ed. pp. 727-728, Elsevier, St. Louis, 2016.
  6. Marcinowska A, Warland J, Brearley M, Dobson J. A novel approach to treatment of lymphangiosarcoma in a boxer dog. J Small Anim Pract 2013;54:334-337. https://doi.org/10.1111/jsap.12054
  7. Lenard ZM, Foster SF, Tebb AJ, Russell NJ, O'Hara AJ, Lester NV. Lymphangiosarcoma in two cats. J Feline Med Surg 2007;9:161-167. https://doi.org/10.1016/j.jfms.2006.09.005
  8. Puff C, Herder V, Philipp A, Baumgartner W. Lymphangiosarcoma in the nictitating membrane of a horse. J Vet Diagn Invest 2008;20:108-110. https://doi.org/10.1177/104063870802000124
  9. Halsey CH, Worley DR, Curran K, Charles JB, Ehrhart EJ. The use of novel lymphatic endothelial cell-specific immuno-histochemical markers to differentiate cutaneous angiosarcomas in dogs. Vet Comp Oncol 2016;14:236-244. https://doi.org/10.1111/vco.12088
  10. Withrow SJ, Vail DM, Page RL. Small Animal Clinical Oncology. 5th ed. pp. 370-383, Elservier Saunders, St. Louis, 2013.
  11. Chung KC, Kim HJ, Jeffers LL. Lymphangiosarcoma (Stewart-Treves syndrome) in postmastectomy patients. J Hand Surg Am 2000;25:1163-1168. https://doi.org/10.1053/jhsu.2000.18490
  12. Sagartz JE, Lairmore MD, Haines D, Sheafor SE, Couto CG. Lymphangiosarcoma in a young dog. Vet Pathol 1996;33:353-356. https://doi.org/10.1177/030098589603300316
  13. Williams JH. Lymphangiosarcoma of dogs: a review. J S Afr Vet Assoc 2005;76:127-131. https://doi.org/10.4102/jsava.v76i3.413
  14. Itoh T, Mikawa K, Mikawa M, Nibe K, Uchida K. Lymphangiosarcoma in a dog treated with surgery and chemotherapy. J Vet Med Sci 2004;66:197-199. https://doi.org/10.1292/jvms.66.197
  15. Gross TL, Ihrke PJ, Walder EJ, Affolter VK. Interface Diseases of the Dermal-Epidermal Junction. In: Gross TL, Ihrke PJ, Walder EJ, Affolter VK, Skin Diseases of the Dog and Cat: Clinical and Histopathologic Diagnosis. 2nd ed. pp. 753-757, Blackwell Publishing, Oxford, 2005.
  16. Kim JH, Yoon H, Yoon HY, Eom K, Sung HJ, Kim JH. Successful management of lymphangiosarcoma in a puppy using a tyrosine kinase inhibitor. Can Vet J 2018;59:367-372.