한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제38권6호
  • /
  • Pages.279-284
  • /
  • 2021
  • /
  • 1598-298X(pISSN)
  • /
  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지
DOI QR코드

DOI QR Code

Clinical and Immunohistochemical Features of Intracardiac Leiomyoma in a Dog

  • Yoon, Hyun-Woo (Department of Veterinary Internal Medicine, College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University) ;
  • Kim, Keon (Department of Veterinary Internal Medicine, College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University) ;
  • Park, Jun-Young (Department of Veterinary Internal Medicine, College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University) ;
  • Kim, Min-Soo (Department of Veterinary Internal Medicine, College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University) ;
  • Ju, Jae-Beom (Department of Veterinary Internal Medicine, College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University) ;
  • Lee, Chang-Min (Department of Veterinary Internal Medicine, College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University) ;
  • Suh, Guk-Hyun (Department of Veterinary Internal Medicine, College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University)
  • 투고 : 2021.05.07
  • 심사 : 2021.11.19
  • 발행 : 2021.12.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

A 10-year-old spayed female Yorkshire terrier dog with a history of pleural effusion and dyspnea for a week was referred to the Veterinary Teaching Hospital. Radiography revealed pulmonary edema and pleural effusion. A mass infiltrating the right atrial lumen and especially the supra-tricuspid valve was identified with echocardiography. The mass was diagnosed as intracardiac neoplasia. Symptomatic treatment was prescribed to alleviate the symptoms of heart failure. Despite symptomatic treatment, the patient died a few days later. After obtaining consent from the owner, necropsy and histopathological evaluation were performed. The result was consistent with cardiac leiomyoma, and the diagnosis was confirmed by immunohistochemical staining. To the authors' knowledge, this case is the first report of intracardiac leiomyoma in a dog in Korea.

키워드

과제정보

This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. 2019R1F1A1060984).

참고문헌

  1. Ahuja AK, Kumar S, Kumar A, Muddarangiah, Sobti D. Surgical management of vaginal leiomyoma in bitch. Int J Sci Env Technol 2017; 6: 2392-2395.
  2. Brown NO, Patnaik AK, MacEwen EG. Canine hemangiosarcoma: retrospective analysis of 104 cases. J Am Vet Med Assoc 1985; 186: 56-58.
  3. Cole PA. Association of canine splenic hemangiosarcomas and hematomas with nodular lymphoid hyperplasia or siderotic nodules. J Vet Diagn Invest 2012; 24: 759-762. https://doi.org/10.1177/1040638712447580
  4. Fang BR, Ng YT, Yeh CH. Intravenous leiomyomatosis with extension to the heart: echocardiographic features: a case report. Angiology 2007; 58: 376-379. https://doi.org/10.1177/0003319707302504
  5. Gallay J, Belanger MC, Helie P, Cote E, Johnson TO, Peters ME. Cardiac leiomyoma associated with advanced atrioventricular block in a young dog. J Vet Cardiol 2011; 13: 71-77. https://doi.org/10.1016/j.jvc.2010.11.003
  6. Gidlewski J, Petrie JP. Therapeutic pericardiocentesis in the dog and cat. Clin Tech Small Anim Pract 2005; 20: 151-155. https://doi.org/10.1053/j.ctsap.2005.05.002
  7. Hammer AS, Couto CG, Filppi J, Getzy D, Shank K. Efficacy and toxicity of VAC chemotherapy (vincristine, doxorubicin, and cyclophosphamide) in dogs with hemangiosarcoma. J Vet Intern Med 1991; 5: 160-166. https://doi.org/10.1111/j.1939-1676.1991.tb00943.x
  8. Hong KH, Kim KS, Lee HY, Choi J. Urethral leiomyoma complicated with lower urinary tract obstruction in a dog. J Vet Clin 2012; 29: 181-185.
  9. Kang MH, Kim DY, Park HM. Ectopic thyroid carcinoma infiltrating the right atrium of the heart in a dog. Can Vet J 2012; 53: 177-181.
  10. Kisseberth WC. Neoplasia of the heart. In: Withrow SJ, Vali DM, editors. Withrow & MacEwen's small animal clinical oncology. St. Louis: Saunders Elsevier. 2007: 809-814.
  11. Krotje LJ, Ware WA, Niyo Y. Intracardiac rhabdomyosarcoma in a dog. J Am Vet Med Assoc 1990; 197: 368-371.
  12. Lamerato-Kozicki AR, Helm KM, Jubala CM, Cutter GC, Modiano JF. Canine hemangiosarcoma originates from hematopoietic precursors with potential for endothelial differentiation. Exp Hematol 2006; 34: 870-878. https://doi.org/10.1016/j.exphem.2006.04.013
  13. Liptak JM, Forrest LJ. Soft tissue sarcomas. In: Withrow SJ, Vali DM, editors. Withrow & MacEwen's small animal clinical oncology. St. Louis: Saunders Elsevier. 2007: 425-454.
  14. Machida N, Hoshi K, Kobayashi M, Katsuda S, Yamane Y. Cardiac myxoma of the tricuspid valve in a dog. J Comp Pathol 2003; 129: 320-324. https://doi.org/10.1016/S0021-9975(03)00049-5
  15. Melo IS, Belo F, Gouveia R, Anjos R. Primary cardiac leiomyoma of the ventricular septum: a rare form of pediatric intracardiac tumor. Pediatr Cardiol 2012; 33: 649-651. https://doi.org/10.1007/s00246-012-0161-7
  16. Natanzon A, Kronzon I. Pericardial and pleural effusions in congestive heart failure-anatomical, pathophysiologic, and clinical considerations. Am J Med Sci 2009; 338: 211-216. https://doi.org/10.1097/maj.0b013e3181a3936f
  17. Oksanen A. Haemangiosarcoma in dogs. J Comp Pathol 1978; 88: 585-595. https://doi.org/10.1016/0021-9975(78)90012-9
  18. Radi ZA, Metz A. Canine cardiac rhabdomyoma. Toxicol Pathol 2009; 37: 348-350. https://doi.org/10.1177/0192623309332991
  19. Ware WA. Cardiac neoplasia. In: Bonagura JD, Kirk RW, editors. Kirk's current veterinary therapy XII: small animal practice. Philadelphia: WB Saunders Elsevier. 1995: 873-876.
  20. Ware WA, Hopper DL. Cardiac tumors in dogs: 1982-1995. J Vet Intern Med 1999; 13: 95-103. https://doi.org/10.1892/0891-6640(1999)013<0095:CTID>2.3.CO;2
  21. Yahaya JJ. Primary leiomyoma of the left ventricle leading to sudden and unexpected death in a 74-year-old male: a case report. Egypt J Forensic Sci 2020; 10: 32. https://doi.org/10.1186/s41935-020-00207-1
  22. Yamamoto S, Hoshi K, Hirakawa A, Chimura S, Kobayashi M, Machida N. Epidemiological, clinical and pathological features of primary cardiac hemangiosarcoma in dogs: a review of 51 cases. J Vet Med Sci 2013; 75: 1433-1441. https://doi.org/10.1292/jvms.13-0064