Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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A Case of Primary Squamous Cell Carcinoma of The Thyroid Gland

갑상선에서 발생한 원발성 편평상피세포암 1예

  • Kang, Sihyung (Department of otorhinolaryngology-Head and neck surgery, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine) ;
  • Park, Gi Cheol (Department of otorhinolaryngology-Head and neck surgery, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine)
  • 강시형 (성균관대학교 삼성창원병원 이비인후 두경부외과학교실) ;
  • 박기철 (성균관대학교 삼성창원병원 이비인후 두경부외과학교실)
  • Received : 2021.09.30
  • Accepted : 2021.11.12
  • Published : 2021.11.30
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Abstract

Primary squamous cell carcinoma of thyroid is a very rare malignant tumor with poor prognosis. It is usually diagnosed as an advanced disease infiltrating adjacent organs, and characterized by aggressive clinical course with an average postoperative survival time of less than 1 year. Recently, we had a 79- year-old woman with a painful neck mass who was diagnosed as primary squamous cell carcinoma of thyroid gland. She underwent total thyroidectomy and selective neck dissection(level III, VI) with no further postoperative managements such as radiation therapy or chemotherapy; she died of poor general condition and pneumonia resulting from rapid progression of the lesion on the 38th day after surgery. We report this case with a review of relevant literatures.

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References

  1. Huang TY, Assor D. Primary squamous cell carcinoma of the thyroid gland: A report of four cases. Am J Clin Pathol. 1971;55:93-98. https://doi.org/10.1093/ajcp/55.1.93
  2. Ibrahim MIS, Jusoh YR, Adam NN, Mohamad I. Primary squamous cell carcinoma of the thyroid gland. Iranian Journal of Otorhinolaryngology. 2018;30:65-68.
  3. Shim HS, Kwon OJ, Ko JS, Park JJ, Kim JP, Jeong CR, et al. Meta-analysis of squamous cell carcinoma of thyroid. Korean Journal of Otorhinolaryngology-Head and Neck Surgery. 2013;56:425-430. https://doi.org/10.3342/kjorl-hns.2013.56.7.425
  4. Sarda AK, Bal S, Arunabh, Singh MK, Kapur MM. Squamous cell carcinoma of the thyroid. J Surg Oncol. 1988;39:175-178. https://doi.org/10.1002/jso.2930390308
  5. Goldman RL. Primary squamous cell carcinoma of the thyroid gland: Report of a case and review of the literature. Am Surg. 1964;30:247-252.
  6. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises: Case 1929-1975. N Engl J Med. 1975;292:186-193.
  7. Goldberg HM, Harvey P. Squamous cell cyst of the thyroid: With special reference to the aetiology of squamous epithelium in the human thyroid. Br J Surg. 1956;43:565-569. https://doi.org/10.1002/bjs.18004318203
  8. Mobini J, Krouse TB, Klinghoffer JF. Squamous cell carcinoma arising in a thyroglossal duct cyst. Am Surg. 1974;40:290-294.
  9. Korovin GS, Kuriloff DB, Cho HT, Sobol SM. Squamous cell carcinoma of the thyroid: a diagnostic dilemma. Ann Otol Rhinol Laryngol. 1989;98:59-65. https://doi.org/10.1177/000348948909800113
  10. Saito K, Kuratomi Y, Yamamoto K, Saito T, Kuzuya T, Yoshida S, et al. Primary squamous cell carcinoma of the thyroid associated with marked leukocytosis and hypercalcemia. Cancer 1981;48:2080-2083. https://doi.org/10.1002/1097-0142(19811101)48:9<2080::AID-CNCR2820480927>3.0.CO;2-N
  11. Harada T, Shimaoka K, Yakumaru K, Ito K. Squamous cell carcinoma of the thyroid gland -- transition from adenocarcinoma. J Surg Oncol. 1982;19:36-43. https://doi.org/10.1002/jso.2930190111
  12. Kampsen EB, Jager N, Max MH. Squamous cell carcinoma of the thyroid: A report of two cases. J Surg Oncol. 1977;9:567-568. https://doi.org/10.1002/jso.2930090607
  13. Cook AM, Vini L, Harmer C. Squamous cell carcinoma of the thyroid: Outcome of treatment in 16 patients. Eur J Surg Oncol. 1999;25:606-609. https://doi.org/10.1053/ejso.1999.0715
  14. Kumar PV, Malekhusseini SA, Talei AR. Primary squamous cell carcinoma of the thyroid diagnosed by fine needle aspiration cytology: A report of two cases. Acta Cytol. 1999;43:659-662. https://doi.org/10.1159/000331162
  15. Ito Y, Hirokawa M, Higashiyama T, Kihara M, Tomoda C, Takamura Y, et al. Biological behavior of papillary carcinoma of the thyroid including squamous cell carcinoma components and prognosis of patients who underwent locally curative surgery. J Thyroid Res. 2012;2012:230283.
  16. Prakash A, Kukreti SC, Sharma MP. Primary squamous cell carcinoma of the thyroid gland. Int Surg. 1968;50:538-541.