대한암한의학회지 (Journal of Korean Traditional Oncology)

  • 제26권1호
  • /
  • Pages.29-37
  • /
  • 2021
  • /
  • 1975-244X(pISSN)
  • /
  • 2765-4850(eISSN)
대한암한의학회 (Korean Association of Traditional Oncology)
권호 표지
DOI QR코드

DOI QR Code

암 환자와 건강인의 심박변이도 및 맥파 특징 비교

Comparison of Heart Rate Variability and Pulse Wave Characteristics between Cancer Patients and Healthy Subjects

  • 김수현 (원광대학교 전주한방병원 체질의학과) ;
  • 염지윤 (우석대학교 부속한방병원 사상체질과) ;
  • 오승윤 (우석대학교 부속한방병원 사상체질과) ;
  • 박수정 (우석대학교 부속한방병원 사상체질과)
  • Kim, Su-Hyun (Department of Korean Internal Medicine, Korean Medicine Cancer Center) ;
  • Yeum, Ji-Yoon (Department of Sasang Constitutional Medicine, Woosuk University Korean Medicine Hospital) ;
  • Oh, Seung-Yun (Department of Sasang Constitutional Medicine, Woosuk University Korean Medicine Hospital) ;
  • Park, Soo-Jung (Department of Sasang Constitutional Medicine, Woosuk University Korean Medicine Hospital)
  • 투고 : 2021.11.09
  • 심사 : 2021.12.15
  • 발행 : 2021.12.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Objectives: The purpose of this study is to examine whether heart rate variability (HRV) and pulse wave of cancer patients can be used as indicators of their health status and prognosis. Methods: We retrospectively compared HRV, pulse wave and body mass index (BMI) of cancer patients and healthy individuals who visited W hospital from November of 2020 to October of 2021. Results: As a result of comparing HRV and pulse wave parameters between cancer patients and healthy subjects, among HRV indices, mean heart rate (MHR), standard deviation of normal to normal (SDNN) and total power (TP), very low frequency (VLF) showed significant differences between two groups. Cancer patients' pulse wave parameters showed more rapid and superficial than that of healthy subjects. Also, cancer patients weighed less and had lower BMI. Conclusion: For increased MHR, decreased SDNN, rapid and superficial pulse wave can be indicators of poor prognosis of cancer patients, keep monitoring HRV and pulse wave can help to manage patients efficiently.

키워드

참고문헌

  1. Yang K, Kim J, Chun M, Ahn MS, Chon E, Park J, Jung M. Factors to improve distress and fatigue in Cancer survivorship; further understanding through text analysis of interviews by machine learning. BMC Cancer 21(1):741, 2021 https://doi.org/10.1186/s12885-021-08438-8
  2. Kim K, Kim JS. Factors influencing health-related quality of life among Korean cancer survivors. Psychooncology 26(1):81-7, 2017 https://doi.org/10.1002/pon.4105
  3. You SJ, Son SE, Kang HW, Lyu YS. A Study on Emotional Characteristics with the CoreSeven-Emotions Inventory (CSEI), Based on Seven Emotions (七情) in Cancer Patients. J Orient Neuropsychiatry 27(2):119-30, 2016 https://doi.org/10.7231/JON.2016.27.2.119
  4. Hartmann R, Schmidt FM, Sander C, Hegerl U. Heart Rate Variability as Indicator of Clinical State in Depression. Front Psychiatry 9:735, 2018 https://doi.org/10.3389/fpsyt.2018.00735
  5. Paek JE. The Study on the 0rigin of Pulse rate diagonsis & Pulse rate diagnosis in . J Soc Korean Med Diagn 2(1):225-248, 1998
  6. Nam CW, Oh SY, Kim K, Joo JC. Reliability of Pulse Wave Analyzer and Heart Rate Variability Analyzer. J Tradit Korean Med 17(1):139-49, 2009
  7. Choi YS, Kim KY, Hwang SY, Kim JY, Lee SW, Kim HH, Joo JC. Characteristic of the pulse wave in hypertension using pulse analyzer with array piezoresistive sensor. J Meridian & Acupoint 24(3):105-16, 2007
  8. Kim JH, Jeon YJ. A Review on Clinical Studies on Metabolic Disease Using a Pulse Tonometry Device. J Int Korean Med 39(4):612-23, 2018 https://doi.org/10.22246/jikm.2018.39.4.612
  9. Kim JH, Kim JY. A Review on Clinical Studies on Gynecological Disease by Using a Pulse Diagnosis Device. J Korean Obstet Gynecol 29(3):23-34, 2016 https://doi.org/10.15204/JKOBGY.2016.29.3.023
  10. Nishikawa H, Goto M, Fukunishi S, Asai A, Nishiguchi S, Higuchi K. Cancer Cachexia: Its Mechanism and Clinical Significance. Int J Mol Sci 22(16):2021
  11. Park SW, Lee DW, Park JW, Ryoo SB, Shin R, Jeong SY, Park KJ. Impact of body mass index on overall survival after surgery for colorectal cancer. Korean J Clin Oncol 12(2):91-6, 2016 https://doi.org/10.14216/kjco.16015
  12. Nam UJ. Treatment and Approach for Patients Complaining of Chronic Pain. Korean J Med 73(2):S794-805, 2007
  13. Stark DP, House A. Anxiety in cancer patients. Br J Cancer 83(10):1261-7, 2000 https://doi.org/10.1054/bjoc.2000.1405
  14. Park H, Oh S, Noh Y, Kim JY, Kim JH. Heart Rate Variability as a Marker of Distress and Recovery: The Effect of Brief Supportive Expressive Group Therapy With Mindfulness in Cancer Patients. Integr Cancer Ther 17(3):825-31, 2018 https://doi.org/10.1177/1534735418756192
  15. Nolan J, Batin PD, Andrews R, Lindsay SJ, Brooksby P, Mullen M, et al. Prospective study of heart rate variability and mortality in chronic heart failure: results of the United Kingdom heart failure evaluation and assessment of risk trial (UK-heart). Circulation 98(15):1510-6, 1998 https://doi.org/10.1161/01.CIR.98.15.1510
  16. Engel G, Cho S, Ghayoumi A, Yamazaki T, Chun S, Fearon WF, et al. Prognostic significance of PVCs and resting heart rate. Ann Noninvasive Electrocardiol 12(2):121-9, 2007 https://doi.org/10.1111/j.1542-474X.2007.00150.x
  17. Parker MM, Shelhamer JH, Natanson C, Alling DW, Parrillo JE. Serial cardiovascular variables in survivors and nonsurvivors of human septic shock: heart rate as an early predictor of prognosis. Crit Care Med 15(10):923-9, 1987 https://doi.org/10.1097/00003246-198710000-00006
  18. Kim G, Park S, Kim Y. A study on the Heart Rate Variability(HRV) in Post Mastectomy Women. Korea J Orient Med 17(1):141-51, 2011
  19. Kloter E, Barrueto K, Klein SD, Scholkmann F, Wolf U. Heart rate variability as a prognostic factor for cancer survival-a systematic review. Frontiers in physiology 9:623, 2018 https://doi.org/10.3389/fphys.2018.00623
  20. Kim OH, Choi JE, Woon JW, Yoo HS. The Effects of Moxibustion on Heart Rate Variability in Cancer Patients. J Kor Tradit Oncology 16(1):15-31, 2011 https://doi.org/10.15432/JKTO.2011.16.1.015
  21. Mozos I, Mihaescu R. Pulse wave velocity and central hemodynamic indices in patients with malignant solid tumors. Jokull 65(9):200-14, 2015
  22. Choi Y, Kim S, Kwon O, Park H, Kim J, Choi W, et al. Cold-Heat and Excess-Deficiency Pattern Identification Based on Questionnaire, Pulse, and Tongue in Cancer Patients: A Feasibility Study. J Korean Med 42(1):1-11, 2021
  23. Lee JY. Characteristics of radial pulse wave in metastatic cancer patients. Master's thesis. Seoul:Kyunghee University, 2014
  24. Kim GC, Park SW, Kim YS, Kim YH. A Study on the Pulse Wave Parameter in Post Mastectomy Women. Korean J Acupunct 28(4):101-12, 2011