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Characterization of Venous Involvement in Vasculo-Behçet Disease

  • Lee, Na Hyeon (Department of Thoracic and Cardiovascular Surgery, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine) ;
  • Bae, Miju (Department of Thoracic and Cardiovascular Surgery, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine) ;
  • Jin, Moran (Department of Thoracic and Cardiovascular Surgery, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine) ;
  • Chung, Sung Woon (Department of Thoracic and Cardiovascular Surgery, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine) ;
  • Lee, Chung Won (Department of Thoracic and Cardiovascular Surgery, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine) ;
  • Jeon, Chang Ho (Department of Radiology, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine)
  • 투고 : 2020.04.21
  • 심사 : 2020.09.19
  • 발행 : 2020.12.05

초록

Background: Behçet disease is a chronic inflammatory disorder with a varying etiology. Herein, we report the involvement of peripheral veins in Behçet disease and discuss the treatment thereof. Methods: Thirty-four patients with venous involvement in vasculo-Behçet disease were retrospectively analyzed over 15 years. We reviewed the clinical manifestations, treatment choices, and complications of these patients. Results: Deep vein thrombosis (DVT) was observed in 24 patients (70.59%) and varicose veins in 19 (52.94%). Immunosuppressive treatment was administered to all patients due to the pathological feature of vein wall inflammation. In patients with DVT, anticoagulation therapy was also used, but post-thrombotic syndrome was observed in all patients along with chronic luminal changes. Eleven patients with isolated varicose veins underwent surgery; although symptoms and lesions recurred in half of these patients, no cases of secondary DVT occurred. Conclusion: When DVT was diagnosed in patients with Behçet disease, there was no cure for the lesions. Ultrasonographic abnormalities were observed in all patients, and post-thrombotic syndrome remained to varying degrees. In cases of isolated varicose veins in patients with Behçet disease, DVT did not occur after surgical treatment. If the activity of Behçet disease is controlled, surgical correction of varicose veins is preferable.

키워드

참고문헌

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피인용 문헌

  1. Corrigendum: Characterization of Venous Involvement in Vasculo-Behçet Disease vol.54, pp.1, 2020, https://doi.org/10.5090/kjtcs.20.027e1
  2. Epidemiologic and Etiological Features of Korean Patients With Behçet's Disease vol.28, pp.4, 2021, https://doi.org/10.4078/jrd.2021.28.4.183