Acknowledgement
This work was financially supported by the research fund of Chungnam National University (Seon-Hwan Kim) and the National Research Foundation of Korea (NRF) grant funded by the Korea Government (MEST) (NRF-2016K1A3A1A08953546, NRF-2015R1A2A2A01003597).
References
- Janssen-Heijnen MLG et al (2015) Variation in causes of death in patients with non-small cell lung cancer according to stage and time since diagnosis. Ann Oncol 26:902-907 https://doi.org/10.1093/annonc/mdv061
- Richer AL et al (2015) Genomic profiling toward precision medicine in non-small cell lung cancer: getting beyond EGFR. Pharmacogenom Personal Med 8:63-79 https://doi.org/10.2147/PGPM.S52845
- McCormick F (2015) KRAS as a therapeutic target. Clin Cancer Res 21:1797-1801 https://doi.org/10.1158/1078-0432.CCR-14-2662
- Knickelbein K, Zhang L (2015) Mutant KRAS as a critical determinant of the therapeutic response of colorectal cancer. Genes Dis 2:4-12 https://doi.org/10.1016/j.gendis.2014.10.002
- Dolgin E (2017) The greatest hits of the human genome. Nature 551:427-431 https://doi.org/10.1038/d41586-017-07291-9
- Naugler WE, Karin M (2008) NF-kappa B and cancer-identifying targets and mechanisms. Curr Opin Genet Dev 18:19-26 https://doi.org/10.1016/j.gde.2008.01.020
- Dan HC et al (2008) Akt-dependent regulation of NF-kappa B is controlled by mTOR and Raptor in association with IKK. Genes Dev 22:1490-1500 https://doi.org/10.1101/gad.1662308
- Tran Q et al (2017) TMEM39A and human diseases: a brief review. Toxicol Res 33:205-209 https://doi.org/10.5487/TR.2017.33.3.205
- Park J et al (2017) Recognition of transmembrane protein 39A as a tumor-specific marker in brain tumor. Toxicol Res 33:63-69 https://doi.org/10.5487/TR.2017.33.1.063
- Varade J et al (2012) Replication study of 10 genes showing evidence for association with multiple sclerosis: validation of TMEM39A, IL12B and CLBL genes. Mult Scler J 18:959-965 https://doi.org/10.1177/1352458511432741
- Sjoblom T et al (2006) The consensus coding sequences of human breast and colorectal cancers. Science 314:268-274 https://doi.org/10.1126/science.1133427
- Rafferty J et al (2016) Peptide therapeutics and the pharmaceutical industry: barriers encountered translating from the laboratory to patients. Curr Med Chem 23:4231-4259 https://doi.org/10.2174/0929867323666160909155222
- Brinckerhoff LH et al (1999) Terminal modifications inhibit proteolytic degradation of an immunogenic MART-1(27-35) peptide: implications for peptide vaccines. Int J Cancer 83:326-334 https://doi.org/10.1002/(SICI)1097-0215(19991029)83:3<326::AID-IJC7>3.0.CO;2-X
- Plotnikov A et al (2015) The nuclear translocation of ERK1/2 as an anticancer target. Nat Commun 6:1
- Pearce LR, Komander D, Alessi DR (2010) The nuts and bolts of AGC protein kinases. Nat Rev Mol Cell Biol 11:9-22 https://doi.org/10.1038/nrm2822
- Netea-Maier RT et al (2016) Modulation of inflammation by autophagy: consequences for human disease. Autophagy 12:245-260 https://doi.org/10.1080/15548627.2015.1071759
- Soleymani-Goloujeh M et al (2018) Effects of N-terminal and C-terminal modification on cytotoxicity and cellular uptake of amphiphilic cell penetrating peptides. Artif Cells Nanomed Biotechnol 46(Suppl 1):91-103 https://doi.org/10.1080/21691401.2017.1414823
- Varisli L, Cen O, Vlahopoulos S (2019) Dissecting pharmacological effects of Chloroquine in cancer treatment: interference with inflammatory signaling pathways. Immunology. https://doi.org/10.1111/imm.13160
- Marqus S, Pirogova E, Piva TJ (2017) Evaluation of the use of therapeutic peptides for cancer treatment. J Biomed Sci 24:21 https://doi.org/10.1186/s12929-017-0328-x
- Nelson AR et al (2007) Myristoyl-based transport of peptides into living cells. Biochemistry 46:14771-14781 https://doi.org/10.1021/bi701295k
- Gao H et al (2017) A method to generate and analyze modified myristoylated proteins. ChemBioChem 18:324-330 https://doi.org/10.1002/cbic.201600608
Cited by
- Induction of Apoptosis by Coptisine in Hep3B Hepatocellular Carcinoma Cells through Activation of the ROS-Mediated JNK Signaling Pathway vol.21, pp.15, 2020, https://doi.org/10.3390/ijms21155502
- Indole-6-carboxaldehyde prevents oxidative stress-induced mitochondrial dysfunction, DNA damage and apoptosis in C2C12 skeletal myoblasts by regulating the ROS-AMPK signaling pathway vol.16, pp.4, 2020, https://doi.org/10.1007/s13273-020-00102-9
- Loganin Inhibits Lipopolysaccharide-Induced Inflammation and Oxidative Response through the Activation of the Nrf2/HO-1 Signaling Pathway in RAW264.7 Macrophages vol.44, pp.6, 2021, https://doi.org/10.1248/bpb.b21-00176
- Coptisine induces autophagic cell death through down-regulation of PI3K/Akt/mTOR signaling pathway and up-regulation of ROS-mediated mitochondrial dysfunction in hepatocellular carcinoma Hep3B cells vol.697, 2021, https://doi.org/10.1016/j.abb.2020.108688
- Spermidine Attenuates Oxidative Stress-Induced Apoptosis via Blocking Ca 2+ Overload in Retinal Pigment Epithelial Cells Independently of ROS vol.22, pp.3, 2021, https://doi.org/10.3390/ijms22031361
- Urban Aerosol Particulate Matter Promotes Necrosis and Autophagy via Reactive Oxygen Species-Mediated Cellular Disorders that Are Accompanied by Cell Cycle Arrest in Retinal Pigment Epithelial Cells vol.10, pp.2, 2020, https://doi.org/10.3390/antiox10020149
- ROS-Mediated Anti-Tumor Effect of Coptidis Rhizoma against Human Hepatocellular Carcinoma Hep3B Cells and Xenografts vol.22, pp.9, 2021, https://doi.org/10.3390/ijms22094797
- Approaches for the discovery of new cell-penetrating peptides vol.16, pp.5, 2020, https://doi.org/10.1080/17460441.2021.1851187
- Induction of Apoptosis by Isoalantolactone in Human Hepatocellular Carcinoma Hep3B Cells through Activation of the ROS-Dependent JNK Signaling Pathway vol.13, pp.10, 2020, https://doi.org/10.3390/pharmaceutics13101627
- Suppression of Lipopolysaccharide-Induced Inflammatory and Oxidative Response by 5-Aminolevulinic Acid in RAW 264.7 Macrophages and Zebrafish Larvae vol.29, pp.6, 2021, https://doi.org/10.4062/biomolther.2021.030
- Schisandrae Fructus ethanol extract attenuates particulate matter 2.5-induced inflammatory and oxidative responses by blocking the activation of the ROS-dependent NF-κB signaling pathway vol.15, pp.6, 2020, https://doi.org/10.4162/nrp.2021.15.6.686