Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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Overlap syndrome of Miller-Fisher syndrome/Pharyngeal-Cervical-Brachial variant-Guillain Barre Syndrome with anti-ganglioside complex antibodies

  • Lee, Suk-yoon (Department of Neurology, Inje University Busan Paik Hospital, Inje University College of Medicine) ;
  • Oh, Seong-il (Department of Neurology, Inje University Busan Paik Hospital, Inje University College of Medicine) ;
  • Huh, So-Young (Department of Neurology, Kosin University College of Medicine) ;
  • Shin, Kyong Jin (Department of Neurology, Inje University Haeundae Paik Hospital) ;
  • Kim, Jong Kuk (Peripheral Neuropathy Research Center, Dong-A University College of Medicine) ;
  • Yoon, Byeol-A (Peripheral Neuropathy Research Center, Dong-A University College of Medicine)
  • Received : 2020.07.11
  • Accepted : 2020.08.11
  • Published : 2020.10.31
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Abstract

Guillain-Barré syndrome (GBS) and Miller Fisher syndrome (MFS) can present with overlapping features. A 56-year-old female developed ptosis and diplopia after an upper respiratory infection, and presented with facial palsy, dysarthria, brachial weakness, ataxia, and areflexia. Mild weakness of both legs appeared after a few days. Anti-ganglioside complex antibody were positive to IgG GM1/GQ1b and GQ1b/sulfatide antibodies. The present case suggests that the manifestation of overlap between MFS/PCB variants and GBS could be caused by antiganglioside complex antibodies.

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References

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