Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Malignant Anterior Uveal Melanoma Masquerading as Limbal Melanoma in a Shih-Tzu Dog with Recurrences of Hyphema

  • Susanti, Lina (Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Seo, Kangmoon (Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Kang, Seonmi (Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University)
  • Received : 2020.07.15
  • Accepted : 2020.10.14
  • Published : 2020.10.30
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Abstract

A 14-year-old neutered-male Shih-Tzu was referred for glaucoma and hyphema accompanied by systemic hypertension. After topical corticosteroid and antiglaucoma medications, the left eye (OS) progressed phthisically, but ocular hypertension redevelop one-year-and-seven-months later. Suspected limbal melanoma developed in peripheral cornea/limbal sclera with heavily pigmented cornea OS. Ultrasound biomicroscopy and ocular ultrasonography differentiated ciliary body origin-heterogeneous mass from limbal mass. Persistent hyphema and pigmented cornea might obscure intraocular lesion and advanced diagnostic methods played a crucial role. Unlike the generally benign limbal melanoma, aggressive treatment was recommended for uveal tumor. Histopathology of enucleated OS confirmed malignant uveal melanoma with chronic hypertensive vasculopathy.

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References

  1. Brown SA, Henik RA. Systemic hypertension. In: Smith FWK, Tilley LP, Oyama MA, Sleeper MM, editors. Manual of Canine and Feline Cardiology. 5th ed. Missouri: Elsevier. 2016: 275-284.
  2. Esson DW. Uveal melanoma. In: Clinical Atlas of Canine and Feline Ophthalmic Disease. 1st ed. IOWA: Wiley-Blackwell. 2015: 200-201.
  3. Giuliano EA, Chappell R, Fischer B, Dubielzig RR. A match observational study of canine survival with primary intraocular melanocytic neoplasia. Vet Ophthalmol 1999; 2: 185-190. doi:10.1046/j.1463-5224.1999.00080.x.
  4. Hendrix VHD. Diseases and surgery of the canine anterior uvea. In: Gellat KN, Gilger BC, Kern TJ, editors. Veterinary Ophthalmology. 5th ed. IOWA: Willey-Blackwell. 2013: 1146-1198.
  5. LeBlanc NL, Stepien RL, Bentley E. Ocular lesions associated with systemic hypertension in dogs: 65 cases (2005-2007). J Am Vet Med Assoc 2011; 238: 915-921. doi: 10.2460/javma.238.7.915.
  6. Ledbetter EC, Gilger BC. Diseases and surgery of the canine cornea and sclera. In: Gellat KN, Gilger BC, Kern TJ, editors. Veterinary Ophthalmology. 5th ed. IOWA: Willey-Blackwell. 2013: 976-1049.
  7. Maggs DJ. Diseases of the cornea and sclera. In: Maggs D, Miller P, Ofri R, editors. Slatter's Fundamentals of Veterinary Ophthalmology. 6th ed. Missouri: Elsevier. 2018: 213-253.
  8. McLelllan GJ, Narfstrom K. The fundus. In: Gould D, McLellan G, editors. BSAVA Manual of Canine and Feline Ophthalmology. 3rd ed. Gloucester: BSAVA. 2017: 322-356.
  9. Miller PE. Diseases of the uvea. In: Maggs D, Miller P, Ofri R, editors. Slatter's Fundamentals of Veterinary Ophthalmology. 6th ed. Missouri: Elsevier. 2018: 254-278.
  10. Mitchell N. The sclera, episclera and limbus. In: Gould D, McLellan G, editors. BSAVA Manual of Canine and Feline Ophthalmology. 3rd ed. Gloucester: BSAVA. 2017: 232-240.
  11. Peiffer RL, Wilcock BP, Yin H. The pathogenesis and significance of pre-iridal fibrovascular membrane in domestic animals. Vet Pathol 1990; 27: 41-45. doi: 10.1177/030098589002700106.
  12. Sisson D, Kittleson MD. Management of heart failure: principles of treatment, therapeutic strategies, and pharmacology. In: Sisson D, Moise NS, Fox PR, editors. Textbook of Canine and Feline Cardiology. 2nd ed. Philadelphia: Saunders. 1999: 216-250.
  13. Watte C, Pot S. The uveal tract. In: Gould D, McLellan G, editors. BSAVA Manual of Canine and Feline Ophthalmology. 3rd ed. Gloucester: BSAVA. 2017: 241-272.
  14. Wilcock BP, Peiffer RL. Morphology and behavior of primary ocular melanomas in 91 dogs. Vet Pathol 1986; 23: 418-424. doi: 10.1177/030098588602300411.